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Bupropion, formerly called amfebutamone, and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is indicated in the treatment of major depressive disorder and seasonal affective disorder and to support smoking cessation. It is a norepinephrine–dopamine reuptake inhibitor (NDRI). Some evidence-based guidelines support…
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effects dopamine treatment use also norepinephrine antidepressants hydroxybupropion drug may fda reuptake disorder however approved smoking wellbutrin associated risk depression
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Bupropion | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Bupropion | Addiction liability | Low | 1.00 | infobox |
| Bupropion | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Bupropion | ATC code | N06AX12 (WHO) | 1.00 | infobox |
| Bupropion | Bioavailability | Unknown | 1.00 | infobox |
| Bupropion | CAS Number | 34911-55-2 Y[PubChem] 31677-93-7 (HCl)905818-69-1 HBr) | 1.00 | infobox |
| Bupropion | CAS Number | 31677-93-7 (HCl) | 1.00 | infobox |
| Bupropion | CAS Number | 905818-69-1 HBr) | 1.00 | infobox |
| Bupropion | ChEBI | CHEBI:3219 Y | 1.00 | infobox |
| Bupropion | ChEMBL | ChEMBL894 Y | 1.00 | infobox |
| Bupropion | ChemSpider | 431 Y | 1.00 | infobox |
| Bupropion | Chirality | Racemic mixture | 1.00 | infobox |
| Bupropion | CompTox Dashboard (EPA) | DTXSID7022706 | 1.00 | infobox |
| Bupropion | Drug class | Norepinephrine–dopamine reuptake inhibitor (NDRI); antidepressant | 1.00 | infobox |
| Bupropion | DrugBank | DB01156 Y | 1.00 | infobox |
| Bupropion | Elimination half-life | Bupropion: alpha: 0.5–1.04 beta: 11 h | 1.00 | infobox |
| Bupropion | Elimination half-life | alpha: 0.5–1.04 | 1.00 | infobox |
| Bupropion | Elimination half-life | beta: 11 h | 1.00 | infobox |
| Bupropion | Elimination half-life | Hydroxybupropion: 20 h | 1.00 | infobox |
| Bupropion | Elimination half-life | Threohydrobupropion: 37 h | 1.00 | infobox |
| Bupropion | Elimination half-life | Erythrohydrobupropion: 33 h | 1.00 | infobox |
| Bupropion | Excretion | Urine: 87% (0.5% unchanged) | 1.00 | infobox |
| Bupropion | Excretion | Feces: 10% | 1.00 | infobox |
| Bupropion | Formula | C13H18ClNO | 1.00 | infobox |
| Bupropion | IUPHAR/BPS | 7135 | 1.00 | infobox |
| Bupropion | KEGG | D07591 Y | 1.00 | infobox |
| Bupropion | KEGG | as HCl: D00817 Y | 1.00 | infobox |
| Bupropion | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Bupropion | Legal status | BR: Class C1 (Other controlled substances) | 1.00 | infobox |
| Bupropion | Legal status | CA: ℞-only | 1.00 | infobox |
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