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Agonist

An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the agonist, while an inverse agonist causes an action opposite to that of the agonist.

Types of agonists, Mechanism of action & Activity

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Overview

Etymology

Types of agonists

Mechanism of action

Activity

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Map overview Semantic statistics

Agonist

Nodes65
Edges64
Triples35
Avg. degree1.97
Density0.030769
Components1

How this topic connects Entity context

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Agonist

Top relations

related to Types of agonists · 17
Agonist → Agents, An, Another, Calcium, D-serine, For, Full, However, HT1A, Inverse, IP3, It, NMDA, Oliceridine, One, Partial, Receptors
related to Mechanism of action · 8
Agonist → As, For, GPCR, NMDA, Other, The, This, Two
is a · 4
Agonist → agent that binds to the same receptor binding-site as an agonist for that receptor and inhibits the constitutive activity of the receptor, chemical that activates a receptor to produce a biological response, substance that creates the same bodily responses but does not bind to the same receptor.An endogenous agonist for a particular receptor is a compound naturally produced by the b…, type of agonist that binds permanently to a receptor through the formation of covalent bonds.A biased agonist is an agent that binds to a receptor without affecting the same sig…
related to Potency · 4
Agonist → EC50, Potency, The, The EC50
causes · 1
Agonist → an action opposite to that of the agonist
see also · 1
Agonist → Allosteric

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Important terminology

receptor response agonists endogenous receptors potency action nmda cell drug needed binding biological inverse bind example conformational produce causes antagonist

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Agonistcausesan action opposite to that of the agonist0.90text
Agonistis achemical that activates a receptor to produce a biological response0.90text
Agonistis asubstance that creates the same bodily responses but does not bind to the same receptor.An endogenous agonist for a particular receptor is a compound naturally produced by the b…0.90text
Agonistis aagent that binds to the same receptor binding-site as an agonist for that receptor and inhibits the constitutive activity of the receptor0.90text
Agonistis atype of agonist that binds permanently to a receptor through the formation of covalent bonds.A biased agonist is an agent that binds to a receptor without affecting the same sig…0.90text
Agonistrelated to Mechanism of actionAs0.60section
Agonistrelated to Mechanism of actionThe0.60section
Agonistrelated to Mechanism of actionThis0.60section
Agonistrelated to Mechanism of actionTwo0.60section
Agonistrelated to Mechanism of actionNMDA0.60section
Agonistrelated to Mechanism of actionFor0.60section
Agonistrelated to Mechanism of actionGPCR0.60section

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    Min side: 3
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