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Dimethyltryptamine

Dimethyltryptamine (DMT), also known as N,N-dimethyltryptamine (N,N-DMT), is a serotonergic hallucinogen and investigational drug of the tryptamine family that occurs naturally in many plants and animals. DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen.

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3D model (JSmol)
Interactive image
Addiction liability
None or very low
ATC code
None
Bioavailability
Very low and inactive (except with MAOITooltip monoamine oxidase inhibitor)
Boiling point
160 °C (320 °F) at 0.6 Torr (80 Pa) also reported as 80–135 °C (176–275 °F) at 0.03 Torr (4.0 Pa)
CAS Number
61-50-7 Y

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Overview

Use and effects

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

Natural occurrence

History

Society and culture

Research

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Map overview Semantic statistics

Dimethyltryptamine

Nodes556
Edges555
Triples135
Avg. degree2
Density0.003597
Components1

How this topic connects Entity context

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Dimethyltryptamine

Top relations

related to Biosynthesis · 19
Dimethyltryptamine → AADC, CH3, DMT, In, INMT, Its, L-tryptophan, N-dimethyltryptamine, N-methyltransferase, N-methyltryptamine, NMT, No, S-adenosylhomocysteine, S-adenosylmethionine, SAH, SAM, The, This, Tryptamine
Legal status · 9
Dimethyltryptamine → AU: S9 (Prohibited substance), BR: Class F2 (Prohibited psychotropics), CA: Schedule III, DE: Anlage I (Authorized scientific use only), EU: Illegal, SE: Illegal, UK: Class A, UN: Psychotropic Schedule I, US: Schedule I
Metabolites · 5
Dimethyltryptamine → DMT-N-oxide (DMT-NO) (3–28%), Indole-3-acetic acid (IAA, 3-IAA) (63–97%), N-Methyltryptamine (NMT), Others, Tryptamine
Duration of action · 4
Dimethyltryptamine → Inhalation: ≤15 min, Intramuscular: 30–60 min, Intravenous: ≤30 min, Oral with MAOITooltip monoamine oxidase inhibitor: 4–6 hours
Onset of action · 4
Dimethyltryptamine → Inhalation: 10–15 seconds, Intramuscular: 2–5 min, Intravenous: ≤2–5 min, Oral with MAOITooltip monoamine oxidase inhibitor: ≤1 hour
Elimination half-life · 2
Dimethyltryptamine → Alone: 5–19 min, With MAOITooltip monoamine oxidase inhibitor: 1–4 hours
has effect · 2
Dimethyltryptamine → According, DMT
3D model (JSmol) · 1
Dimethyltryptamine → Interactive image
Addiction liability · 1
Dimethyltryptamine → None or very low
ATC code · 1
Dimethyltryptamine → None

Important terminology Word statistics

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Important terminology

dmt effects serotonin also may ayahuasca psychedelic used inmt study drug human receptor found brain mg known tryptamine orally use

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dimethyltryptamine3D model (JSmol)Interactive image1.00infobox
DimethyltryptamineAddiction liabilityNone or very low1.00infobox
DimethyltryptamineATC codeNone1.00infobox
DimethyltryptamineBioavailabilityVery low and inactive (except with MAOITooltip monoamine oxidase inhibitor)1.00infobox
DimethyltryptamineBoiling point160 °C (320 °F) at 0.6 Torr (80 Pa) also reported as 80–135 °C (176–275 °F) at 0.03 Torr (4.0 Pa)1.00infobox
DimethyltryptamineCAS Number61-50-7 Y1.00infobox
DimethyltryptamineChEBICHEBI:28969 Y1.00infobox
DimethyltryptamineChEMBLChEMBL12420 Y1.00infobox
DimethyltryptamineChemSpider5864 Y1.00infobox
DimethyltryptamineCompTox Dashboard (EPA)DTXSID601100531.00infobox
DimethyltryptamineDensity1.099 g/cm31.00infobox
DimethyltryptamineDependence liabilityNone or very low1.00infobox
DimethyltryptamineDrug classSerotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen1.00infobox
DimethyltryptamineDrugBankDB01488 Y1.00infobox
DimethyltryptamineDuration of actionInhalation: ≤15 min1.00infobox
DimethyltryptamineDuration of actionIntravenous: ≤30 min1.00infobox
DimethyltryptamineDuration of actionIntramuscular: 30–60 min1.00infobox
DimethyltryptamineDuration of actionOral with MAOITooltip monoamine oxidase inhibitor: 4–6 hours1.00infobox
DimethyltryptamineECHA InfoCard100.000.4631.00infobox
DimethyltryptamineElimination half-lifeAlone: 5–19 min1.00infobox
DimethyltryptamineElimination half-lifeWith MAOITooltip monoamine oxidase inhibitor: 1–4 hours1.00infobox
DimethyltryptamineExcretionUrine1.00infobox
DimethyltryptamineFormulaC12H16N21.00infobox
DimethyltryptamineIUPHAR/BPS1411.00infobox
DimethyltryptamineKEGGC08302 Y1.00infobox
DimethyltryptamineLegal statusAU: S9 (Prohibited substance)1.00infobox
DimethyltryptamineLegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
DimethyltryptamineLegal statusCA: Schedule III1.00infobox
DimethyltryptamineLegal statusDE: Anlage I (Authorized scientific use only)1.00infobox
DimethyltryptamineLegal statusUK: Class A1.00infobox

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