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Dimethyltryptamine: History, Community, Culture & Applications

Dimethyltryptamine (DMT), also known as N,N-dimethyltryptamine (N,N-DMT), is a serotonergic hallucinogen and investigational drug of the tryptamine family that occurs naturally in many plants and animals. DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen.

Language: English [EN]
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Dimethyltryptamine topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Dimethyltryptamine.

Related topics
544
Source areas
11
Connected nodes
555
Extracted relationships
135
Concept neighborhoods
50
Bridge connections
555

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 167 topics
Chemistry · 127 topics
Use and effects · 97 topics
Pharmacology · 48 topics
Natural occurrence · 26 topics
Interactions · 25 topics
History · 22 topics
Adverse effects · 14 topics
Society and culture · 11 topics
Research · 4 topics
Overdose · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
Addiction liability
None or very low
ATC code
None
Bioavailability
Very low and inactive (except with MAOITooltip monoamine oxidase inhibitor)
Boiling point
160 °C (320 °F) at 0.6 Torr (80 Pa) also reported as 80–135 °C (176–275 °F) at 0.03 Torr (4.0 Pa)
CAS Number
61-50-7 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Use and effects

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

Natural occurrence

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Dimethyltryptamine connects Entity context

The extracted context around Dimethyltryptamine shows recurring relationship patterns in the source. For example, Dimethyltryptamine → AADC, CH3, DMT, In, INMT, Its, L-tryptophan, N-dimethyltryptamine, N-methyltransferase, N-methyltryptamine, NMT, No, S-adenosylhomocysteine, S-adenosylmethionine, SAH, SAM, The, This, Tryptamine Another extracted example is Dimethyltryptamine → AU: S9 (Prohibited substance), BR: Class F2 (Prohibited psychotropics), CA: Schedule III, DE: Anlage I (Authorized scientific use only), EU: Illegal, SE: Illegal, UK: Class A, UN: Psychotropic Schedule I, US: Schedule I. Use these groups to spot repeated connection types before inspecting the individual relationships.

Dimethyltryptamine

Top relations

related to Biosynthesis · 19
Dimethyltryptamine → AADC, CH3, DMT, In, INMT, Its, L-tryptophan, N-dimethyltryptamine, N-methyltransferase, N-methyltryptamine, NMT, No, S-adenosylhomocysteine, S-adenosylmethionine, SAH, SAM, The, This, Tryptamine
Legal status · 9
Dimethyltryptamine → AU: S9 (Prohibited substance), BR: Class F2 (Prohibited psychotropics), CA: Schedule III, DE: Anlage I (Authorized scientific use only), EU: Illegal, SE: Illegal, UK: Class A, UN: Psychotropic Schedule I, US: Schedule I
Metabolites · 5
Dimethyltryptamine → DMT-N-oxide (DMT-NO) (3–28%), Indole-3-acetic acid (IAA, 3-IAA) (63–97%), N-Methyltryptamine (NMT), Others, Tryptamine
Duration of action · 4
Dimethyltryptamine → Inhalation: ≤15 min, Intramuscular: 30–60 min, Intravenous: ≤30 min, Oral with MAOITooltip monoamine oxidase inhibitor: 4–6 hours
Onset of action · 4
Dimethyltryptamine → Inhalation: 10–15 seconds, Intramuscular: 2–5 min, Intravenous: ≤2–5 min, Oral with MAOITooltip monoamine oxidase inhibitor: ≤1 hour
Elimination half-life · 2
Dimethyltryptamine → Alone: 5–19 min, With MAOITooltip monoamine oxidase inhibitor: 1–4 hours
has effect · 2
Dimethyltryptamine → According, DMT
3D model (JSmol) · 1
Dimethyltryptamine → Interactive image
Addiction liability · 1
Dimethyltryptamine → None or very low
ATC code · 1
Dimethyltryptamine → None

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dmt effects serotonin also may ayahuasca psychedelic used inmt study drug human receptor found brain mg known tryptamine orally use

Dimethyltryptamine relationships Subject–Predicate–Object triples

TTTA extracted 135 structured relationships around Dimethyltryptamine. Examples in this analysis include Dimethyltryptamine → 3D model (JSmol) → Interactive image and Dimethyltryptamine → Addiction liability → None or very low. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Dimethyltryptamine3D model (JSmol)Interactive image1.00infobox
DimethyltryptamineAddiction liabilityNone or very low1.00infobox
DimethyltryptamineATC codeNone1.00infobox
DimethyltryptamineBioavailabilityVery low and inactive (except with MAOITooltip monoamine oxidase inhibitor)1.00infobox
DimethyltryptamineBoiling point160 °C (320 °F) at 0.6 Torr (80 Pa) also reported as 80–135 °C (176–275 °F) at 0.03 Torr (4.0 Pa)1.00infobox
DimethyltryptamineCAS Number61-50-7 Y1.00infobox
DimethyltryptamineChEBICHEBI:28969 Y1.00infobox
DimethyltryptamineChEMBLChEMBL12420 Y1.00infobox
DimethyltryptamineChemSpider5864 Y1.00infobox
DimethyltryptamineCompTox Dashboard (EPA)DTXSID601100531.00infobox
DimethyltryptamineDensity1.099 g/cm31.00infobox
DimethyltryptamineDependence liabilityNone or very low1.00infobox
DimethyltryptamineDrug classSerotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen1.00infobox
DimethyltryptamineDrugBankDB01488 Y1.00infobox
DimethyltryptamineDuration of actionInhalation: ≤15 min1.00infobox
DimethyltryptamineDuration of actionIntravenous: ≤30 min1.00infobox
DimethyltryptamineDuration of actionIntramuscular: 30–60 min1.00infobox
DimethyltryptamineDuration of actionOral with MAOITooltip monoamine oxidase inhibitor: 4–6 hours1.00infobox
DimethyltryptamineECHA InfoCard100.000.4631.00infobox
DimethyltryptamineElimination half-lifeAlone: 5–19 min1.00infobox
DimethyltryptamineElimination half-lifeWith MAOITooltip monoamine oxidase inhibitor: 1–4 hours1.00infobox
DimethyltryptamineExcretionUrine1.00infobox
DimethyltryptamineFormulaC12H16N21.00infobox
DimethyltryptamineIUPHAR/BPS1411.00infobox
DimethyltryptamineKEGGC08302 Y1.00infobox
DimethyltryptamineLegal statusAU: S9 (Prohibited substance)1.00infobox
DimethyltryptamineLegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
DimethyltryptamineLegal statusCA: Schedule III1.00infobox
DimethyltryptamineLegal statusDE: Anlage I (Authorized scientific use only)1.00infobox
DimethyltryptamineLegal statusUK: Class A1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Dimethyltryptamine bring nearby vocabulary together. In this analysis, examples include Intravenous, Injection and Administration. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • psychedelic drug
    • Intravenous
    • Injection
    • Administration
    • Effects
    • Experiences
    • Receptors
    • Endogenous
    • 5-ht2a
    • Blood
    • Concentrations
    • Dose
    • Use
  • investigational drug
    • Use
    • Used
    • Oral
    • Tryptamine
    • Doses
    • Psychedelic
    • Inmt
    • Receptor
    • Serotonin
    • May
    • Effects
    • Plants
  • psychedelic experience
    • Intravenous
    • Injection
    • Administration
    • Effects
    • Experiences
    • Receptors
    • Endogenous
    • 5-ht2a
    • Blood
    • Concentrations
    • Dose
    • Receptor
  • 5-ht2a
    • Serotonin
    • Receptor
    • Receptors
    • Tolerance
    • Psychedelics
    • Effects
    • Psychedelic
    • Administration
    • Use
    • May
    • Intravenous
    • Human
  • endogenous
    • Brain
    • Human
    • Study
    • Psychedelic
    • Inmt
    • Receptors
    • Produced
    • Concentrations
    • Used
    • Use
    • Doses
    • Receptor
  • parenteral administration
    • Intravenous
    • Blood
    • Injection
    • Psychedelic
    • Tolerance
    • Doses
    • Effects
    • Oral
    • 5-ht2a
    • Concentrations
    • Reported
    • Studies
  • intravenous administration
    • Injection
    • Intravenous
    • Blood
    • Tolerance
    • Psychedelic
    • Mg
    • Doses
    • Studies
    • Effects
    • Oral
    • Known
    • 5-ht2a
  • blood–brain barrier
    • Human
    • Concentrations
    • Endogenous
    • Inmt
    • Blood
    • Brain
    • Doses
    • Psychedelic
    • Studies
    • Injection
    • Dose
    • Dmt

Connections between topic areas Semantic bridges

For Dimethyltryptamine, one of the stronger structural bridges in this analysis connects Dimethyltryptamine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Dimethyltryptamine — Overview · splits 388 ⟂ 168
Dimethyltryptamine — Chemistry · splits 428 ⟂ 128
Dimethyltryptamine — Use and effects · splits 458 ⟂ 98
Dimethyltryptamine — Pharmacology · splits 507 ⟂ 49
Dimethyltryptamine — Natural occurrence · splits 529 ⟂ 27
Dimethyltryptamine — Interactions · splits 530 ⟂ 26
Dimethyltryptamine — History · splits 533 ⟂ 23
Dimethyltryptamine — Adverse effects · splits 541 ⟂ 15
Dimethyltryptamine — Society and culture · splits 544 ⟂ 12
Dimethyltryptamine — Research · splits 551 ⟂ 5
Dimethyltryptamine — Overdose · splits 552 ⟂ 4

Map overview Semantic statistics

Dimethyltryptamine

Nodes556
Edges555
Triples135
Avg. degree2
Density0.003597
Components1

Source & methodology

TTTA analyzes the structure around Dimethyltryptamine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Dimethyltryptamine · EN edition · Analysis: TopicsToTalkAbout

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