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Methyltransferase: Applications, Function & Types

Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. The most common class of methyltransferases is class I, all of which contain a Rossmann fold for binding S-Adenosyl methionine (SAM). Class II methyltransferases contain a SET domain, which are…

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Methyltransferase topic overview

The analysis highlights Applications, Function and Types as prominent areas in the source structure around Methyltransferase.

Related topics
97
Source areas
6
Connected nodes
103
Extracted relationships
69
Related term clusters
26
Bridge connections
103

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Types · 51 topics
Function · 23 topics
Clinical significance · 10 topics
Overview · 9 topics
Applications in drug discovery and development · 2 topics
Examples · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Types

Clinical significance

Applications in drug discovery and development

Examples

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Methyltransferase connects Entity context

The extracted context around Methyltransferase shows recurring relationship patterns in the source. For example, Methyltransferase → Archived, Catechol-O-methyltransferase, COMT, HNMT, Important, Like, Methyl, N-methyltransferase, Natural, NPMTs, O-methyltransferases, PNMT, Reflective, SAH, SAM, Wayback Machine Another extracted example is Methyltransferase → Alanine, Known, N-alpha, N-terminal, Proline, RCC-1, Retinoblastoma, SAH, SAM, Serine, The N-terminal, When RCC-1, X-Proline-Lysine. Use these groups to spot repeated connection types before inspecting the individual relationships.

Methyltransferase

Top relations

related to Natural product methyltransferases · 16
Methyltransferase → Archived, Catechol-O-methyltransferase, COMT, HNMT, Important, Like, Methyl, N-methyltransferase, Natural, NPMTs, O-methyltransferases, PNMT, Reflective, SAH, SAM, Wayback Machine
related to N-terminal methyltransferases · 13
Methyltransferase → Alanine, Known, N-alpha, N-terminal, Proline, RCC-1, Retinoblastoma, SAH, SAM, Serine, The N-terminal, When RCC-1, X-Proline-Lysine
related to DNA/RNA methyltransferases · 11
Methyltransferase → DNA, DNMT1, DNMT2, DNMT3, Many, Methylation, O-methylation, RNA, S-adenosylmethionine, Specific RNA, TRDMT1
related to Histone methyltransferases · 11
Methyltransferase → Arginine, DNA, Either, H3, H4, Histone, Increased, Lysine, Methyl, RNAs, SAM
related to Clinical significance · 9
Methyltransferase → Cancer, DNA, DNMT, Fragile, ICF, Inhibition, Plasmid, Rett, RNA
has application · 3
Methyltransferase → Recent, S-Adenosyl, SAM
related to Examples · 3
Methyltransferase → Catechol-O-methyltransferaseDNA, Examples, Methyltetrahydrofolate-homocysteine

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

methyltransferases dna methylation methyl protein sam histone class methionine enzymes rna types methylated proteins group substrates cancer enzyme pathways transfer

Methyltransferase relationships Subject–Predicate–Object triples

TTTA extracted 69 structured relationships around Methyltransferase. Examples in this analysis include ICF → instance of → anomalous DNA methylation is associated with genetic disorders and Methyltransferase → has application → Recent. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ICFinstance ofanomalous DNA methylation is associated with genetic disorders0.80text
Rett syndromeinstance ofanomalous DNA methylation is associated with genetic disorders0.80text
and Fragile X syndromeinstance ofanomalous DNA methylation is associated with genetic disorders0.80text
Methyltransferasehas applicationRecent0.60section
Methyltransferasehas applicationS-Adenosyl0.60section
Methyltransferasehas applicationSAM0.60section
Methyltransferaserelated to Clinical significanceDNA0.60section
Methyltransferaserelated to Clinical significanceICF0.60section
Methyltransferaserelated to Clinical significanceRett0.60section
Methyltransferaserelated to Clinical significanceFragile0.60section
Methyltransferaserelated to Clinical significanceCancer0.60section
Methyltransferaserelated to Clinical significanceInhibition0.60section

Related concept clusters Related term clusters

The concept neighborhoods around Methyltransferase bring nearby vocabulary together. In this analysis, examples include Methyltransferases, Protein and S-adenosyl. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • histone methyltransferases
    • Sam
    • Lysine
    • Regulation
    • Histone
    • Methyltransferases
    • Methyl
    • Dna
    • Examples
    • Gene
    • Protein
    • Rna
    • Genetic
  • protein–dna interactions
    • Methylation
    • Dna
    • Protein
    • Known
    • Methylated
    • Cancer
    • Methyltransferases
    • N-terminal
    • Examples
    • Genetic
    • Many
    • Gene
  • dna repair
    • Methylation
    • Protein
    • Cancer
    • Methyltransferases
    • Genetic
    • Many
    • Gene
    • Methyltransferase
    • Function
    • M5c
    • Regulation
    • Cell
  • histone
    • Lysine
    • Regulation
    • Methyltransferases
    • Examples
    • Genetic
    • Gene
    • Methyltransferase
    • Methylation
    • Dna
    • Sam
    • Protein
    • Function
  • dna methyltransferase enzymes
    • Methylation
    • Protein
    • Group
    • Cancer
    • Methyltransferases
    • Methyl
    • Function
    • Genetic
    • Many
    • Gene
    • Methyltransferase
    • Enzyme
  • methylated dna recognition sites
    • Methylation
    • Protein
    • Cancer
    • Methyltransferases
    • Genetic
    • Many
    • Gene
    • Methyltransferase
    • Function
    • M5c
    • Regulation
    • Cell
  • dna translation
    • Methylation
    • Protein
    • Cancer
    • Methyltransferases
    • Genetic
    • Many
    • Gene
    • Methyltransferase
    • Function
    • M5c
    • Regulation
    • Cell
  • protein–protein interactions
    • Dna
    • Known
    • Methylated
    • N-terminal
    • Examples
    • Types
    • Methylation
    • Sam
    • Function
    • Regulation
    • Cell
    • Methyltransferase

Connections between topic areas Semantic bridges

For Methyltransferase, one of the stronger structural bridges in this analysis connects Methyltransferase with Types. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Methyltransferase — Types · splits 52 ⟂ 52
Methyltransferase — Function · splits 80 ⟂ 24
Methyltransferase — Clinical significance · splits 93 ⟂ 11
Methyltransferase — Overview · splits 94 ⟂ 10
Methyltransferase — Applications in drug discovery and development · splits 101 ⟂ 3
Methyltransferase — Examples · splits 101 ⟂ 3

Map overview Semantic statistics

Methyltransferase

Nodes104
Edges103
Triples69
Avg. degree1.98
Density0.019231
Components1

Source & methodology

TTTA analyzes the structure around Methyltransferase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Function & Types, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Methyltransferase · EN edition · Analysis: TopicsToTalkAbout

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