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Indole

Indole is an organic compound with the formula .mw-parser-output .template-chem2-su{display:inline-block;font-size:80%;line-height:1;vertical-align:-0.35em}.mw-parser-output .template-chem2-su>span{display:block;text-align:left}.mw-parser-output sub.template-chem2-sub{font-size:80%;vertical-align:-0.35em}.mw-parser-output…

History & Applications

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General properties and occurrence

SolidFecesOdorPerfumesCoal tar
23 related topics

Synthetic routes

AnilineEthylene glycolCatalystsFormyltoluidineCyclizations
32 related topics

Chemical reactions of indole

AminesBasicLone pairHydrochloric acidProtonate
44 related topics

Medical applications

TuberculosisMalariaDiabetesCancerMigraines
10 related topics

Topics to explore

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Overview

General properties and occurrence

History

Biosynthesis and function

Detection methods

Medical applications

Synthetic routes

Chemical reactions of indole

General references

  • ISBN ISBN (identifier)
  • Doi Doi (identifier)
  • PMID PMID (identifier)

Advanced semantic analysis

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Map overview Semantic statistics

Indole

Nodes157
Edges156
Triples134
Avg. degree1.99
Density0.012739
Components1

How this topic connects Entity context

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Indole

Top relations

related to General references · 31
Indole → Academic Press, Access, Blackwell Science, Direct, Heterocyclic Chemistry, Highly Enantioselective Iso-Pictet-Spengler Reactions, Houlihan, Indoles, Indoles Part One, ISBN, Joule, Ketoamides, Leighton, Lett, Mills, New York, Org, Oxford, PMID, San Diego
related to Cycloadditions of indole · 12
Indole → C2, C3, Despite, Diels-Alder, For, In, Indoles, Intramolecular, One, Only, Padwa, Pictet-Spengler
related to Electrophilic substitution · 10
Indole → C2, C3, C5, For, Haack, In, N1, Since, The, Vilsmeier
related to Carbon acidity and C2 lithiation · 8
Indole → After, Bergman, C2, Katritzky, N-protected, Reaction, This, Venemalm
related to Other indole-forming reactions · 7
Indole → Bartoli, Diels, Emmerling, Möhlau, Reese, Sundberg, With
has method · 6
Indole → Common, Ehrlich's, For, HPLC, Kovács, Salkowski
related to N–H acidity and organometallic indole anion complexes · 6
Indole → C3, DMF, DMSO, Grignard, In, The
related to Basicity · 5
Indole → C3, N1, Strong, The, Unlike
related to Fischer indole synthesis · 5
Indole → Although, Emil Fischer, Fischer, One, This
related to history · 5
Indole → Adolf, Baeyer, Certain, In, Indigo

Important terminology Word statistics

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Important terminology

indoles tryptophan synthesis substituted derivatives acid c3 electrophilic benzene reaction formula aromatic methods substitution c2 also compounds isbn ring one

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Indoleis aorganic compound with the formula .mw-parser-output .template-chem2-su0.90text
Indoleis asubstituent on a larger molecule0.90text
Indoleis aportmanteau of the words indigo and oleum0.90text
Indoleis adienophile0.90text
serotonininstance ofincluding neurotransmitters0.80text
hydrochloric acid caninstance ofStrong acids0.80text
howeverinstance ofStrong acids0.80text
protonate indoleinstance ofStrong acids0.80text
sodium hydride or n-butyl lithiuminstance ofso that very strong bases0.80text
water-free conditions are required for complete deprotonationinstance ofso that very strong bases0.80text
the sodium or potassium compounds tend to react with electrophiles at nitrogen-1instance ofThe more ionic salts0.80text
whereas the more covalent magnesium compoundsinstance ofThe more ionic salts0.80text

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