Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Methysergide

Methysergide, sold under the brand names Deseril and Sansert, is a monoaminergic medication which is used in the prevention and treatment of migraine and cluster headaches. It has been withdrawn from the market in the United States and Canada due to safety concerns. The drug has also been found to produce psychedelic effects at high doses. It is taken…

History, Community, Culture & Applications

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Methysergide. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
N02CA04 (WHO)
CAS Number
361-37-5 Y
ChEMBL
ChEMBL1065 Y
ChemSpider
9300 Y

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Interactions

Pharmacology

Chemistry

Natural occurrence

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Methysergide

Nodes103
Edges102
Triples88
Avg. degree1.98
Density0.019417
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Methysergide

Top relations

related to Pharmacodynamics · 17
Methysergide → GABA, HT1, HT1A, HT1B, HT1D, HT1E, HT1F, HT2A, HT2B, HT2C, HT3, HT5A, HT6, HT7, It, Methylergonovine, The
related to External links · 12
Methysergide → Discusses Methysergide, ErowidLSD-25, Isomer Design, Isomer DesignSansert, Koehler, Migraine, NovartisHistory, NovartisSansert, Prescribing Information, PubMedLSD-25, Tfelt-Hansen, TiHKAL
related to history · 9
Methysergide → Based, Harold Wolff's, HT, In, Less, Serotonin, Sicuteri, The, This
Legal status · 5
Methysergide → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
is a · 4
Methysergide → agonist of 5-HT1 receptors, mixed agonist of some serotonin receptors, partial agonist of the 5-HT2A and 5-HT2B receptors and also interacts with various other targets.Methysergide antagonizes the effects of serotonin in blood vessels and gastroint…, rapidly converted prodrug of methylergometrine
related to Interactions · 4
Methysergide → DMT, However, Pre-treatment, Since
related to Migraine and cluster headaches · 3
Methysergide → European Medicines Agency, International Headache Society, To
related to Natural occurrence · 3
Methysergide → Argyreia, Hawaiian, Previously
related to Pharmacokinetics · 3
Methysergide → As, Levels, The
related to Analogues · 2
Methysergide → D13H, XC101-D13H

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

serotonin migraine effects methylergonovine receptor cluster psychedelic due drug treatment agonist also methylergometrine used receptors united headaches sansert 5-ht2a 5-ht2b

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Methysergide3D model (JSmol)Interactive image1.00infobox
MethysergideAHFS/Drugs.comInternational Drug Names1.00infobox
MethysergideATC codeN02CA04 (WHO)1.00infobox
MethysergideCAS Number361-37-5 Y1.00infobox
MethysergideChEMBLChEMBL1065 Y1.00infobox
MethysergideChemSpider9300 Y1.00infobox
MethysergideCompTox Dashboard (EPA)DTXSID20233071.00infobox
MethysergideDrug classMonoamine receptor modulator; Antimigraine agent1.00infobox
MethysergideDrugBankDB00247 Y1.00infobox
MethysergideECHA InfoCard100.006.0411.00infobox
MethysergideFormulaC21H27N3O21.00infobox
MethysergideIUPHAR/BPS1341.00infobox
MethysergideKEGGD02357 Y1.00infobox
MethysergideLegal statusAU: S4 (Prescription only)1.00infobox
MethysergideLegal statusBR: Class C1 (Other controlled substances)1.00infobox
MethysergideLegal statusCA: ℞-only1.00infobox
MethysergideLegal statusUK: POM (Prescription only)1.00infobox
MethysergideLegal statusUS: ℞-only1.00infobox
MethysergideMedlinePlusa6030221.00infobox
MethysergideMolar mass353.466 g·mol−11.00infobox
MethysergideOther namesUML-491; 1-Methylmethylergonovine; N-[(2S)-1-Hydroxybutan-2-yl]-1,6-dimethyl-9,10-didehydroergoline-8α-carboxamide; N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide1.00infobox
MethysergidePregnancy categoryAU: C1.00infobox
MethysergidePubChem CID96811.00infobox
MethysergideRoutes of administrationOral1.00infobox
MethysergideTrade namesDeseril, Sansert1.00infobox
MethysergideUNIIXZA9HY6Z981.00infobox
Methysergideis amixed agonist of some serotonin receptors0.90text
Methysergideis arapidly converted prodrug of methylergometrine0.90text
Methysergideis aagonist of 5-HT1 receptors0.90text
Methysergideis apartial agonist of the 5-HT2A and 5-HT2B receptors and also interacts with various other targets.Methysergide antagonizes the effects of serotonin in blood vessels and gastroint…0.90text

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.