Bufotenin

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Bufotenin topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Bufotenin.

Related topics: 220
Source areas: 9
Connected nodes: 230
Extracted relationships: 175
Related term clusters: 43
Bridge connections: 230

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 65 topics

Overview · 54 topics

Use and effects · 31 topics

Natural occurrence · 26 topics

History · 23 topics

Chemistry · 10 topics

Research · 6 topics

Overdose · 4 topics

Side effects · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol): Interactive image
ATC code: None
Bioavailability: Weakly active (with or without MAOITooltip monoamine oxidase inhibitor)
Boiling point: 320 °C (608 °F)
CAS Number: 487-93-4 Y
ChEBI: CHEBI:3210 Y

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Explore different angles and find fresh ideas to shape your next piece of content.

Bufotenin

4Brain-to-blood ratio · 5-MeO-DMT · Psilocin

3Vomiting · Nausea · Hamilton Morris

3Hallucinogen · Toxicity · David E. Nichols

4Substituted tryptamine · Chemical derivative · Dimethyltryptamine

12Serotonergic psychedelic · Neurotransmitter · Alkaloid

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Side effects

Vomiting

Overdose

Pharmacology

Chemistry

Research

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Bufotenin connects Entity context

The extracted context around Bufotenin shows recurring relationship patterns in the source. For example, Bufotenin → Comparing, DMT, EC50, EC50Tooltip, Findings, HO-DMT, HO-T, HT1A, HT1B, HT1D, HT1F, HT2A, HT2C, HT3, HT4, HT6, HT7, IC50, Ki, MeO-DMT Another extracted example is Bufotenin → AcO-DMT, AMS, BuCO-DMT, DMT, HO-AMT, HO-DET, HO-DiPT, HO-DMT, HO-DPT, HO-MET, MeO-DMT, N-methylbufotenin, O-acetylbufotenine, O-methylbufotenin, O-pivalylbufotenine, O-sulfate. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Pharmacodynamics · 24

Bufotenin → Comparing, DMT, EC50, EC50Tooltip, Findings, HO-DMT, HO-T, HT1A, HT1B, HT1D, HT1F, HT2A, HT2C, HT3, HT4, HT6, HT7, IC50, Ki, MeO-DMT

related to Analogues and derivatives · 16

Bufotenin → AcO-DMT, AMS, BuCO-DMT, DMT, HO-AMT, HO-DET, HO-DiPT, HO-DMT, HO-DPT, HO-MET, MeO-DMT, N-methylbufotenin, O-acetylbufotenine, O-methylbufotenin, O-pivalylbufotenine, O-sulfate

related to history · 16

Bufotenin → Anadenanthera, Austrian, Bufo, Bufotenine, Clinical, Césaire Phisalix, French, Gabriel Bertrand, German, Hans Handovsky, Heinrich Wieland, Japanese, Kenya Shimodaira, Schedule, Toshio Hoshino, United States

related to Overdose · 8

Bufotenin → Asian, Central Formosa, Death, Dec, In April, LD50, South Korean, Taiwanese

related to Toads · 8

Bufotenin → Bufo, China, Colorado River, Extracts, Incilius, Mesoamerica, Mesoamerican, Rhinella

Legal status · 6

Bufotenin → AU: S9 (Prohibited substance), CA: Unscheduled, DE: NpSG (Industrial and scientific use only), Illegal in Sweden, UK: Class A, US: Schedule I

related to Morris (2020s) · 6

Bufotenin → DMT, Hamilton Morris, HT3, MeO-DMT, Morris, Zofran

related to Anadenanthera seeds · 5

Bufotenin → Anadenanthera, Caribbean, Central, Columbian, South America

related to Chemistry · 5

Bufotenin → DMT, HO-DMT, HT, MeO-DMT, N-dimethyltryptamine

related to Isbell (1956) · 5

Bufotenin → Anadenanthera, Harris Isbell, Kentucky, Lexington, Public Health Service Hospital

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

effects psychedelic serotonin also 5-meo-dmt toad dmt bufo drug reported found psilocin use mg peripheral receptor morris toads doses higher

Bufotenin relationships Subject–Predicate–Object triples

TTTA extracted 175 structured relationships around Bufotenin. Examples in this analysis include Bufotenin → 3D model (JSmol) → Interactive image and Bufotenin → ATC code → None. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Bufotenin	3D model (JSmol)	Interactive image	1.00	infobox
Bufotenin	ATC code	None	1.00	infobox
Bufotenin	Bioavailability	Weakly active (with or without MAOITooltip monoamine oxidase inhibitor)	1.00	infobox
Bufotenin	Boiling point	320 °C (608 °F)	1.00	infobox
Bufotenin	CAS Number	487-93-4 Y	1.00	infobox
Bufotenin	ChEBI	CHEBI:3210 Y	1.00	infobox
Bufotenin	ChEMBL	ChEMBL416526 Y	1.00	infobox
Bufotenin	ChemSpider	9839 Y	1.00	infobox
Bufotenin	CompTox Dashboard (EPA)	DTXSID0048894	1.00	infobox
Bufotenin	Drug class	Serotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist	1.00	infobox
Bufotenin	DrugBank	DB01445 Y	1.00	infobox
Bufotenin	Duration of action	POTooltip Oral administration: ~2 hours INTooltip Intranasal administration: 30–90 min SLTooltip Sublingual administration: 30–90 min RECTooltip Rectal administration: ~1 hour I…	1.00	infobox
Bufotenin	ECHA InfoCard	100.006.971	1.00	infobox
Bufotenin	Formula	C12H16N2O	1.00	infobox
Bufotenin	IUPHAR/BPS	144	1.00	infobox
Bufotenin	KEGG	C08299 Y	1.00	infobox
Bufotenin	Legal status	AU: S9 (Prohibited substance)	1.00	infobox
Bufotenin	Legal status	CA: Unscheduled	1.00	infobox
Bufotenin	Legal status	DE: NpSG (Industrial and scientific use only)	1.00	infobox
Bufotenin	Legal status	UK: Class A	1.00	infobox
Bufotenin	Legal status	US: Schedule I	1.00	infobox
Bufotenin	Legal status	Illegal in Sweden	1.00	infobox
Bufotenin	Melting point	146 to 147 °C (295 to 297 °F)	1.00	infobox
Bufotenin	Metabolism	Deamination via MAO-ATooltip monoamine oxidase A and conjugation (glucuronidation, sulfation)	1.00	infobox
Bufotenin	Metabolites	• 5-HIAATooltip 5-Hydroxyindoleacetic acid • Glucuronide and sulfate conjugates	1.00	infobox
Bufotenin	Molar mass	204.273 g·mol−1	1.00	infobox
Bufotenin	Onset of action	POTooltip Oral administration: 20 min INTooltip Intranasal administration: 5–15 min SLTooltip Sublingual administration: 5–15 min RECTooltip Rectal administration: ~15 min INHTo…	1.00	infobox
Bufotenin	Other names	Bufotenine; 5-Hydroxy-N,N-dimethyltryptamine; 5-HO-DMT; 5-OH-DMT; N,N-Dimethyl-5-hydroxytryptamine; N,N-Dimethylserotonin; Dimethylserotonin; Dimethyl-5-HT; Cebilcin; Mappine	1.00	infobox
Bufotenin	PubChem CID	10257	1.00	infobox
Bufotenin	Routes of administration	Oral, intranasal/insufflation, inhalation, sublingual, rectal, intravenous	1.00	infobox

Related concept clusters Related term clusters

The concept neighborhoods around Bufotenin bring nearby vocabulary together. In this analysis, examples include Effects, Serotonin and Psychedelic. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

serotonergic psychedelic
- Effects
- Active
- Use
- Morris
- Produce
- Humans
- Ott
- Anadenanthera
- Serotonin
- Bufo
- Found
- Higher
psychedelic
- Effects
- Active
- Morris
- Produce
- Humans
- Ott
- Anadenanthera
- Use
- Serotonin
- Bufo
- Found
- Higher
Bufotenin
- Effects
- Serotonin
- Psychedelic
- 5-meo-dmt
- Receptor
- Drug
- Mg
- Dmt
- Morris
- Ott
- Like
- Others
bufotenin
- Effects
- Serotonin
- Psychedelic
- 5-meo-dmt
- Receptor
- Drug
- Mg
- Dmt
- Morris
- Ott
- Like
- Others
5-meo-dmt
- Dmt
- Serotonin
- Like
- Psilocin
- Receptor
- 5-ht1a
- Higher
- Effects
- Bufotenin
- Brain
- Psychedelic
- Species
side effects
- Psychedelic
- Produce
- Doses
- Mg
- Like
- Peripheral
- Ott
- Reported
- Serotonergic
- Humans
- Bufotenine
- Others
bufo alvarius: the psychedelic toad of the sonoran desert
- Toad
- Species
- Effects
- Active
- Morris
- Produce
- Many
- Toads
- Bufotenine
- Humans
- Orally
- Ott
adverse effects
- Psychedelic
- Produce
- Doses
- Mg
- Like
- Peripheral
- Ott
- Reported
- Serotonergic
- Humans
- Bufotenine
- Others

Connections between topic areas Semantic bridges

For Bufotenin, one of the stronger structural bridges in this analysis connects Bufotenin with Pharmacology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Bufotenin — Pharmacology · splits 165 ⟂ 66

Bufotenin — Overview · splits 176 ⟂ 55

Bufotenin — Use and effects · splits 199 ⟂ 32

Bufotenin — Natural occurrence · splits 203 ⟂ 28

Bufotenin — History · splits 207 ⟂ 24

Bufotenin — Chemistry · splits 220 ⟂ 11

Bufotenin — Research · splits 224 ⟂ 7

Bufotenin — Overdose · splits 226 ⟂ 5

Map overview Semantic statistics

Bufotenin

Nodes231

Edges230

Triples175

Avg. degree1.99

Density0.008658

Components1

Source & methodology

TTTA analyzes the structure around Bufotenin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Bufotenin · EN edition · Analysis: TopicsToTalkAbout

Bufotenin: History, Applications & Research

Bufotenin topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Use and effects

Side effects

Overdose

Pharmacology

Chemistry

Natural occurrence

History

Research

For the semantics nerds

Advanced semantic analysis

How Bufotenin connects Entity context

Bufotenin

Top relations

Important terminology

Important terminology

Bufotenin relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

Bufotenin

Source & methodology