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Bufotenin

Bufotenin, also known as dimethylserotonin or as 5-hydroxy-N,N-dimethyltryptamine (5-HO-DMT), is a serotonergic psychedelic of the tryptamine family. It is a derivative of the psychedelic dimethyltryptamine (DMT) and of the neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). The compound is an alkaloid found in some species of mushrooms, plants, and…

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3D model (JSmol)
Interactive image
ATC code
None
Bioavailability
Weakly active (with or without MAOITooltip monoamine oxidase inhibitor)
Boiling point
320 °C (608 °F)
CAS Number
487-93-4 Y
ChEBI
CHEBI:3210 Y

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Overview

Use and effects

Side effects

Overdose

Pharmacology

Chemistry

Natural occurrence

History

Research

Advanced semantic analysis

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Map overview Semantic statistics

Bufotenin

Nodes231
Edges230
Triples230
Avg. degree1.99
Density0.008658
Components1

How this topic connects Entity context

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Bufotenin

Top relations

related to Pharmacodynamics · 26
Bufotenin → Comparing, DMT, EC50, EC50Tooltip, Findings, HO-DMT, HO-T, HT1A, HT1B, HT1D, HT1F, HT2A, HT2C, HT3, HT4, HT6, HT7, IC50, In, It
related to history · 20
Bufotenin → Anadenanthera, Austrian, Bufo, Bufotenine, Clinical, Césaire Phisalix, French, Gabriel Bertrand, German, Hans Handovsky, Heinrich Wieland, However, In, It, Japanese, Kenya Shimodaira, Schedule, The, Toshio Hoshino, United States
related to Analogues and derivatives · 17
Bufotenin → AcO-DMT, AMS, BuCO-DMT, DMT, HO-AMT, HO-DET, HO-DiPT, HO-DMT, HO-DPT, HO-MET, MeO-DMT, N-methylbufotenin, O-acetylbufotenine, O-methylbufotenin, O-pivalylbufotenine, O-sulfate, Some
related to External links · 16
Bufotenin → Amazon, Anadenanthera, BluelightBufotenin, Bufo Alvarius, Dandy Bufotenine, ErowidBufotenin, ErowidThe Big, HO-DMT, Isomer DesignBufotenin, Psychedelic Snuff From, PsychonautWikiBufotenin, Thread, TiHKAL, Tripsitter, TripsitterYopo, Trout's NotesPsychoactive Toad Venom
related to Pharmacokinetics · 11
Bufotenin → About, HIAA, However, In, MAO, MeO-DMT, O-methylbufotenin, Only, Orally, The, This
related to Toads · 10
Bufotenin → Bufo, China, Colorado River, Extracts, Incilius, It, Mesoamerica, Mesoamerican, Rhinella, The
related to Overdose · 9
Bufotenin → Asian, Central Formosa, Death, Dec, In April, LD50, South Korean, Taiwanese, The
related to Morris (2020s) · 8
Bufotenin → By, DMT, Hamilton Morris, He, HT3, MeO-DMT, Morris, Zofran
related to Ott (2001) · 8
Bufotenin → At, Free, He, Higher, In, Jonathan Ott, Ott, The
related to Turner & Merlis (1959) · 8
Bufotenin → After, Cohoba, Finally, Merlis, New York, They, Turner, We

Important terminology Word statistics

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Important terminology

effects psychedelic serotonin also 5-meo-dmt toad dmt bufo drug reported found psilocin use mg however peripheral receptor morris toads doses

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Bufotenin3D model (JSmol)Interactive image1.00infobox
BufoteninATC codeNone1.00infobox
BufoteninBioavailabilityWeakly active (with or without MAOITooltip monoamine oxidase inhibitor)1.00infobox
BufoteninBoiling point320 °C (608 °F)1.00infobox
BufoteninCAS Number487-93-4 Y1.00infobox
BufoteninChEBICHEBI:3210 Y1.00infobox
BufoteninChEMBLChEMBL416526 Y1.00infobox
BufoteninChemSpider9839 Y1.00infobox
BufoteninCompTox Dashboard (EPA)DTXSID00488941.00infobox
BufoteninDrug classSerotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist1.00infobox
BufoteninDrugBankDB01445 Y1.00infobox
BufoteninDuration of actionPOTooltip Oral administration: ~2 hours INTooltip Intranasal administration: 30–90 min SLTooltip Sublingual administration: 30–90 min RECTooltip Rectal administration: ~1 hour I…1.00infobox
BufoteninECHA InfoCard100.006.9711.00infobox
BufoteninFormulaC12H16N2O1.00infobox
BufoteninIUPHAR/BPS1441.00infobox
BufoteninKEGGC08299 Y1.00infobox
BufoteninLegal statusAU: S9 (Prohibited substance)1.00infobox
BufoteninLegal statusCA: Unscheduled1.00infobox
BufoteninLegal statusDE: NpSG (Industrial and scientific use only)1.00infobox
BufoteninLegal statusUK: Class A1.00infobox
BufoteninLegal statusUS: Schedule I1.00infobox
BufoteninLegal statusIllegal in Sweden1.00infobox
BufoteninMelting point146 to 147 °C (295 to 297 °F)1.00infobox
BufoteninMetabolismDeamination via MAO-ATooltip monoamine oxidase A and conjugation (glucuronidation, sulfation)1.00infobox
BufoteninMetabolites• 5-HIAATooltip 5-Hydroxyindoleacetic acid • Glucuronide and sulfate conjugates1.00infobox
BufoteninMolar mass204.273 g·mol−11.00infobox
BufoteninOnset of actionPOTooltip Oral administration: 20 min INTooltip Intranasal administration: 5–15 min SLTooltip Sublingual administration: 5–15 min RECTooltip Rectal administration: ~15 min INHTo…1.00infobox
BufoteninOther namesBufotenine; 5-Hydroxy-N,N-dimethyltryptamine; 5-HO-DMT; 5-OH-DMT; N,N-Dimethyl-5-hydroxytryptamine; N,N-Dimethylserotonin; Dimethylserotonin; Dimethyl-5-HT; Cebilcin; Mappine1.00infobox
BufoteninPubChem CID102571.00infobox
BufoteninRoutes of administrationOral, intranasal/insufflation, inhalation, sublingual, rectal, intravenous1.00infobox

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