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Risperidone

Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder, as well as aggressive and self-injurious behaviors associated with autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AX08 (WHO)
Bioavailability
70% (by mouth)
CAS Number
106266-06-2 Y
ChEBI
CHEBI:8871 Y

Topics to explore

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Overview

Medical uses

Adverse effects

Interactions

Pharmacology

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Risperidone

Nodes114
Edges113
Triples148
Avg. degree1.98
Density0.017544
Components1

How this topic connects Entity context

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Risperidone

Top relations

related to Legal status · 16
Risperidone → August, Committee, Drug Administration, European Medicines Agency, European Union, FDA, February, Human Use, In, In December, Long-acting, Medicinal Products, Okedi, On, The FDA's, United States Food
related to Discontinuation · 14
Risperidone → California, Casandra, Casi, Chino Hills, Department, Ed Lyman, Her, In, Pastora, Rancho Cucamonga, San Bernardino County Sheriff's, The British National Formulary, They, West Valley Detention Center
related to Further reading · 13
Risperidone → Biotechnology Information, Bookshelf ID, CYP2D6 Genotype, Dean, In Pratt VM, McLeod HL, Medical Genetics Summaries, National Center, NBK425795, NCBI, PMID, Risperidone Therapy, Rubinstein WS
related to Interactions · 9
Risperidone → Carbamazepine, CYP2D6, If, LSD, P-glycoprotein, Since, SSRI, St John's, The
related to Pharmacodynamics · 9
Risperidone → Although, D-alanine, D-amino, D-serine, HT, HT2A, HT2C, It, These
related to Lawsuits · 7
Risperidone → Arkansas, In April, In August, Janssen Pharmaceuticals Inc, Johnson, The, US
Legal status · 6
Risperidone → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
has effect · 6
Risperidone → About, Atypical, Common, In, Serious, While
related to Autism · 4
Risperidone → Compared, Evidence, Some, The
related to Bipolar disorder · 4
Risperidone → As, In, Second-generation, The

Important terminology Word statistics

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Important terminology

effects side risk disorder treatment antipsychotics may schizophrenia atypical dementia antipsychotic associated weight use approved psychosis long-acting people include bipolar

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Risperidone3D model (JSmol)Interactive image1.00infobox
RisperidoneAHFS/Drugs.comMonograph1.00infobox
RisperidoneATC codeN05AX08 (WHO)1.00infobox
RisperidoneBioavailability70% (by mouth)1.00infobox
RisperidoneCAS Number106266-06-2 Y1.00infobox
RisperidoneChEBICHEBI:8871 Y1.00infobox
RisperidoneChEMBLChEMBL85 Y1.00infobox
RisperidoneChemSpider4895 Y1.00infobox
RisperidoneCompTox Dashboard (EPA)DTXSID80451931.00infobox
RisperidoneDrug classAtypical antipsychotic1.00infobox
RisperidoneDrugBankDB00734 Y1.00infobox
RisperidoneECHA InfoCard100.114.7051.00infobox
RisperidoneElimination half-life20 hours (by mouth), 3–6 days (IM)1.00infobox
RisperidoneExcretionUrinary (70%) feces (14%)1.00infobox
RisperidoneFormulaC23H27FN4O21.00infobox
RisperidoneIUPHAR/BPS961.00infobox
RisperidoneKEGGD00426 Y1.00infobox
RisperidoneLegal statusAU: S4 (Prescription only)1.00infobox
RisperidoneLegal statusBR: Class C1 (Other controlled substances)1.00infobox
RisperidoneLegal statusCA: ℞-only1.00infobox
RisperidoneLegal statusUK: POM (Prescription only)1.00infobox
RisperidoneLegal statusUS: ℞-only1.00infobox
RisperidoneLegal statusEU: Rx-only1.00infobox
RisperidoneLicense dataUS DailyMed: Risperidone1.00infobox
RisperidoneMedlinePlusa6940151.00infobox
RisperidoneMetabolismLiver (CYP2D6 mediated to 9-hydroxyrisperidone)1.00infobox
RisperidoneMolar mass410.493 g·mol−11.00infobox
RisperidonePDB ligand8NU (PDBe, RCSB PDB)1.00infobox
RisperidonePregnancy categoryAU: C1.00infobox
RisperidoneProtein binding90% (parent compound), 77% (active metabolite)1.00infobox

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