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Quetiapine: History, Community, Culture & Applications

Quetiapine (/kwɪˈtaɪ.əpiːn/ kwi-TY-ə-peen), sold under the brand name Seroquel among others, is an atypical antipsychotic medication used in the treatment of schizophrenia, bipolar disorder, and major depressive disorder.

Language: English [EN]
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Quetiapine topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Quetiapine.

Related topics
192
Source areas
8
Connected nodes
200
Extracted relationships
141
Concept neighborhoods
36
Bridge connections
200

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 56 topics
Pharmacology · 43 topics
Medical uses · 33 topics
Overview · 30 topics
Society and culture · 16 topics
Chemistry · 5 topics
History · 5 topics
Overdose · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AH04 (WHO)
Bioavailability
100%
CAS Number
111974-69-7 Y
ChEBI
CHEBI:8707 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Overdose

Pharmacology

Chemistry

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Quetiapine connects Entity context

The extracted context around Quetiapine shows recurring relationship patterns in the source. For example, Quetiapine → D2, D3, D4, D5, Dopamine D1, H1, HT1A, HT1B, HT1D, HT1E, HT1F, HT2A, HT2B, HT2C, HT3, HT6, HT7 Another extracted example is Quetiapine → American, AstraZeneca, August, Canada, During, European Union, FDA, However, In May, November, Q2, Seroquel XR, Seroquel XR's, The, United States, United States FDA. Use these groups to spot repeated connection types before inspecting the individual relationships.

Quetiapine

Top relations

related to Pharmacodynamics · 17
Quetiapine → D2, D3, D4, D5, Dopamine D1, H1, HT1A, HT1B, HT1D, HT1E, HT1F, HT2A, HT2B, HT2C, HT3, HT6, HT7
related to Sustained-release · 16
Quetiapine → American, AstraZeneca, August, Canada, During, European Union, FDA, However, In May, November, Q2, Seroquel XR, Seroquel XR's, The, United States, United States FDA
related to Insomnia · 10
Quetiapine → CITooltip, Danish, Doses, Increases, Laboratory, LDL-C, Regardless, The, These, Z-drugs
related to Lawsuits · 8
Quetiapine → According, AstraZeneca, Department, In April, Justice, Multiple, Seroquel, United States Department
related to Regulatory status · 7
Quetiapine → Drug Administration, FDA, Food, In, United States, US FDA, XR
Legal status · 6
Quetiapine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, NZ: Prescription only, UK: POM (Prescription only), US: ℞-only
related to Abuse potential · 6
Quetiapine → In, It, Q-ball, The, To, While
related to Major depressive disorder · 6
Quetiapine → Australia, Australian Pharmaceutical Benefits Scheme, In, MDD, United Kingdom, United States
has effect · 4
Quetiapine → Dry, Extended, Sources, XR
related to Others · 4
Quetiapine → It, Owing, Parkinson's, Tourette

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

treatment schizophrenia antipsychotics effects disorder seroquel clozapine drug used low use insomnia bipolar united atypical antipsychotic blood may side states

Quetiapine relationships Subject–Predicate–Object triples

TTTA extracted 141 structured relationships around Quetiapine. Examples in this analysis include Quetiapine → 3D model (JSmol) → Interactive image and Quetiapine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Quetiapine3D model (JSmol)Interactive image1.00infobox
QuetiapineAHFS/Drugs.comMonograph1.00infobox
QuetiapineATC codeN05AH04 (WHO)1.00infobox
QuetiapineBioavailability100%1.00infobox
QuetiapineCAS Number111974-69-7 Y1.00infobox
QuetiapineChEBICHEBI:8707 Y1.00infobox
QuetiapineChEMBLChEMBL716 Y1.00infobox
QuetiapineChemSpider4827 Y1.00infobox
QuetiapineCompTox Dashboard (EPA)DTXSID90235461.00infobox
QuetiapineDrug classAtypical antipsychotic1.00infobox
QuetiapineDrugBankDB01224 Y1.00infobox
QuetiapineECHA InfoCard100.131.1931.00infobox
QuetiapineElimination half-life7 hours (parent compound); 9–12 hours (active metabolite, norquetiapine)1.00infobox
QuetiapineExcretionKidney (73%), feces (20%)1.00infobox
QuetiapineFormulaC21H25N3O2S1.00infobox
QuetiapineIUPHAR/BPS501.00infobox
QuetiapineKEGGD08456 Y1.00infobox
QuetiapineLegal statusAU: S4 (Prescription only)1.00infobox
QuetiapineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
QuetiapineLegal statusCA: ℞-only1.00infobox
QuetiapineLegal statusNZ: Prescription only1.00infobox
QuetiapineLegal statusUK: POM (Prescription only)1.00infobox
QuetiapineLegal statusUS: ℞-only1.00infobox
QuetiapineLicense dataUS DailyMed: Quetiapine1.00infobox
QuetiapineMedlinePlusa6980191.00infobox
QuetiapineMetabolismLiver via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine)1.00infobox
QuetiapineMolar mass383.51 g·mol−11.00infobox
QuetiapinePregnancy categoryAU: B31.00infobox
QuetiapinePronunciation/kwɪˈtaɪ.əpiːn/ kwi-TY-ə-peen1.00infobox
QuetiapineProtein binding83%1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Quetiapine bring nearby vocabulary together. In this analysis, examples include Treatment, Effects and Schizophrenia. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Quetiapine
    • Treatment
    • Effects
    • Schizophrenia
    • Associated
    • Insomnia
    • Clozapine
    • Low
    • Drug
    • Used
    • Antipsychotics
    • Doses
    • Atypical
  • quetiapine
    • Treatment
    • Effects
    • Schizophrenia
    • Associated
    • Insomnia
    • Clozapine
    • Low
    • Drug
    • Used
    • Antipsychotics
    • Doses
    • Atypical
  • atypical antipsychotic
    • Drugs
    • Antipsychotic
    • Atypical
    • Medication
    • Antipsychotics
    • Clozapine
    • Depressive
    • Drug
    • Effects
    • Bipolar
    • Major
    • Associated
  • bipolar disorder
    • Disorder
    • Depressive
    • Major
    • Treatment
    • Associated
    • Approved
    • Used
    • Xr
    • Drug
    • Schizophrenia
    • Seroquel
    • Fda
  • major depressive disorder
    • Depressive
    • Disorder
    • Major
    • Treatment
    • Used
    • Approved
    • Associated
    • Xr
    • Risk
    • Drug
    • Schizophrenia
    • Seroquel
  • movement disorder
    • Depressive
    • Major
    • Treatment
    • Approved
    • Used
    • Associated
    • Xr
    • Drug
    • Schizophrenia
    • Seroquel
    • Fda
    • Quetiapine
  • bipolar i disorder
    • Disorder
    • Depressive
    • Major
    • Treatment
    • Associated
    • Approved
    • Used
    • Xr
    • Drug
    • Schizophrenia
    • Seroquel
    • Fda
  • adverse effects
    • Side
    • Drugs
    • Less
    • Risk
    • Associated
    • Insomnia
    • Quetiapine
    • Low
    • Used
    • Sedation
    • Doses
    • Blood

Connections between topic areas Semantic bridges

For Quetiapine, one of the stronger structural bridges in this analysis connects Quetiapine with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
QuetiapineAdverse effects · splits 144 ⟂ 57
QuetiapinePharmacology · splits 157 ⟂ 44
QuetiapineMedical uses · splits 167 ⟂ 34
QuetiapineOverview · splits 170 ⟂ 31
QuetiapineSociety and culture · splits 184 ⟂ 17
QuetiapineChemistry · splits 195 ⟂ 6
QuetiapineHistory · splits 195 ⟂ 6
QuetiapineOverdose · splits 196 ⟂ 5

Map overview Semantic statistics

Quetiapine

Nodes201
Edges200
Triples141
Avg. degree1.99
Density0.00995
Components1

Source & methodology

TTTA analyzes the structure around Quetiapine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Quetiapine · EN edition · Analysis: TopicsToTalkAbout

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