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Mescaline

Mescaline, also known in chemical terms as 3,4,5-trimethoxyphenethylamine, is a naturally occurring psychedelic drug and alkaloid of the phenethylamine and scaline families found in certain cacti like peyote (Lophophora williamsii) and the San Pedro cactus (Echinopsis pachanoi, others).

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
mescaline
ATC code
None
Bioavailability
Unknown (but ≥53%)
Boiling point
180 °C (356 °F) at 12 mmHg
CAS Number
54-04-6 Y

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Overview

Use and effects

Contraindications

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

Natural occurrence

History

Society and culture

Research

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Map overview Semantic statistics

Mescaline

Nodes461
Edges460
Triples372
Avg. degree2
Density0.004338
Components1

How this topic connects Entity context

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Mescaline

Top relations

related to Notable individuals · 75
Mescaline → Aldous Huxley, Alexander Shulgin, Allen Ginsberg, Antonin Artaud, Arthur Heffter, Arthur Kleps, Bryan Wynter, Carlos Santana, Comanche Nation, Crystal Fairy, Cuckoo's Nest, Dalí, Delta Chemical Company, Dick, Disney, Doomed, Fear, First Visit, Flow My Tears, For
related to history · 43
Mescaline → Archaeological, Arthur Heffter, Aztec Empire, Bernardino, Botanical, Canada, Comanche, Ecuador, Ernst Späth, Europeans, Francis, Francisco Hernández, German, He, However, Huichol, In, It, John Raleigh Briggs, Kiowa
has effect · 21
Mescaline → Alexander Shulgin, Buttons, Doses, Have Known, High, However, In, It, Loved, Low, LSD, Microdosing, Nausea, On, Phenethylamines, PiHKAL, San Pedro, Side, Some, The
related to Pharmacodynamics · 19
Mescaline → Besides, DAT, DOx, EC50Tooltip, HIAA, How, However, HT2A, HT2B, HT2C, In, Its EC50Tooltip, Ki, NET, Other, SERT, The, This, TMA
related to Synthesis · 19
Mescaline → Alexander Shulgin, Amide, Cyanohydrin, Ernst Späth's, Ester, Eudesmic, Have Known, Henry, Hofmann, Kolbe, Loved, Ozonolysis, Phenethylamines, PiHKAL, Reduction, Several, THF, This, Treatment
related to Religious use · 15
Mescaline → Comanche, Huichol, Kiowa, Latin American, Mescaline-containing, Mexican, Mexico, Native American, Native American Church, Peru, San Pedro, South American, The, The Huichol, Wixárika
related to Analogues · 13
Mescaline → Deuterated, DOM, DOx, Examples, FLY, N-dimethylmescaline, N-methylmescaline, NBOMe-mescaline, Other, Pachycereus, These, TMA, TMA-1
related to Biosynthesis · 13
Mescaline → COMT, DOPA, In Lophophora, L-DOPA, O-methylation, O-methyltransferase, S-adenosyl, SAM, SAM-dependent, The, These, This, Tyrosine
related to Monoamine oxidase inhibitors · 13
Mescaline → Accordingly, Daniel Trachsel, However, In, It, MAO, MAOI, MAOIs, No, On, RIMA, RIMAs, SSAO
related to Natural occurrence · 13
Mescaline → As, Echinopsis, Gymnocalycium, It, Levels, Lophophora, Moreover, Opuntia, San Pedro, Stenocereus, The, Trichocereus, Turbinicarpus

Important terminology Word statistics

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Important terminology

peyote effects psychedelic use serotonin however cacti first cactus drug also lsd religious mg doses receptor like 5-ht2a may san

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Mescaline3D model (JSmol)Interactive image1.00infobox
MescalineAHFS/Drugs.commescaline1.00infobox
MescalineATC codeNone1.00infobox
MescalineBioavailabilityUnknown (but ≥53%)1.00infobox
MescalineBoiling point180 °C (356 °F) at 12 mmHg1.00infobox
MescalineCAS Number54-04-6 Y1.00infobox
MescalineChEBICHEBI:28346 Y1.00infobox
MescalineChEMBLChEMBL26687 Y1.00infobox
MescalineChemSpider3934 Y1.00infobox
MescalineCompTox Dashboard (EPA)DTXSID802023031.00infobox
MescalineDensity1.067 g/cm31.00infobox
MescalineDrug classSerotonin receptor agonist; Serotonergic psychedelic; Hallucinogen1.00infobox
MescalineDrugBankDB190831.00infobox
MescalineDuration of action6.4–14 hours (range 3.0–22 hours)1.00infobox
MescalineECHA InfoCard100.000.1741.00infobox
MescalineElimination half-life3.6 hours (range 2.6–5.3 hours)1.00infobox
MescalineExcretionUrine (≥92%; 28–60% unchanged, ≥27–31% as TMPAA, 5% as N-Ac-3,4-DiMeO-5-OH-PEA, <0.1% as NAMTooltip N-acetylmescaline)1.00infobox
MescalineFormulaC11H17NO31.00infobox
MescalineKEGGC06546 Y1.00infobox
MescalineLegal statusAU: S9 (Prohibited substance)1.00infobox
MescalineLegal statusBR: Class F2 (Prohibited psychotropics)1.00infobox
MescalineLegal statusCA: Schedule III , except peyote1.00infobox
MescalineLegal statusDE: Anlage I (Authorized scientific use only)1.00infobox
MescalineLegal statusUK: Class A (Plants containing mescaline legal)1.00infobox
MescalineLegal statusUS: Schedule I (with religious use exceptions)1.00infobox
MescalineLegal statusUN: P I (psychoactive cactus like peyote or san pedro uncontrolled)1.00infobox
MescalineMelting point35 to 36 °C (95 to 97 °F)1.00infobox
MescalineMetabolismOxidative deamination, N-acetylation, O-demethylation, conjugation, other pathways1.00infobox
MescalineMetabolites• 3,4,5-Trimethoxyphenyl-acetaldehyde • 3,4,5-Trimethoxyphenylacetic acid • 3,4,5-Trimethoxyphenylethanol • Others1.00infobox
MescalineMolar mass211.261 g·mol−11.00infobox

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