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Dopamine receptor D1

Dopamine receptor D1, also known as DRD1, is one of the two types of D1-like receptor family—receptors D1 and D5. It is a protein that in humans is encoded by the DRD1 gene.

Ligands, Tissue distribution & Protein–protein interactions

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Aliases
DRD1, dopamine receptor D1, DADR, DRD1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1OZ5
Band
5q35.2 · 13 B1|13 28.4 cM
Bgee
caudate nucleus · nucleus accumbens · putamen · gonad · prefrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

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Overview

Tissue distribution

Structure

Function

Ligands

Protein–protein interactions

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Dopamine receptor D1

Nodes121
Edges120
Triples163
Avg. degree1.98
Density0.016529
Components1

How this topic connects Entity context

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Dopamine receptor D1

Top relations

Gene ontology · 83
Dopamine receptor D1 → activation of adenylate cyclase activity, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adult walking behavior, associative learning, astrocyte development, behavioral fear response, behavioral response to cocaine, cell projection, cellular response to catecholamine stimulus, cellular response to dopamine, cerebral cortex GABAergic interneuron migration, ciliary membrane, cilium, conditioned taste aversion, dendrite, dendritic spine, dentate gyrus development, dopamine binding, dopamine metabolic process
Bgee · 19
Dopamine receptor D1 → amygdala, anterior cingulate cortex, Brodmann area 46, Brodmann area 9, caudate nucleus, cingulate gyrus, dorsal striatum, globus pallidus, gonad, lumbar subsegment of spinal cord, neural layer of retina, nucleus accumbens, olfactory tubercle, prefrontal cortex, putamen, right frontal lobe, superior frontal gyrus, temporal lobe, urethra
RNA expression pattern · 19
Dopamine receptor D1 → amygdala, anterior cingulate cortex, Brodmann area 46, Brodmann area 9, caudate nucleus, cingulate gyrus, dorsal striatum, globus pallidus, gonad, lumbar subsegment of spinal cord, neural layer of retina, nucleus accumbens, olfactory tubercle, prefrontal cortex, putamen, right frontal lobe, superior frontal gyrus, temporal lobe, urethra
related to Structure · 16
Dopamine receptor D1 → Agonist, Cryo-EM, D1, D1R, G-protein, Gs-coupled GPCR, Gαs, Interactions, S1985, S1995, S2025, The, TM, TM5, TM6, X-ray
related to Protein–protein interactions · 3
Dopamine receptor D1 → COPG2COPGDNAJC14, D1, Dopamine
Band · 2
Dopamine receptor D1 → 13 B1|13 28.4 cM, 5q35.2
Chr. · 2
Dopamine receptor D1 → Chromosome 13 (mouse), Chromosome 5 (human)
End · 2
Dopamine receptor D1 → 175,444,182 bp, 54,209,724 bp
Aliases · 1
Dopamine receptor D1 → DRD1, dopamine receptor D1, DADR, DRD1A
Available structures · 1
Dopamine receptor D1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1OZ5

Important terminology Word statistics

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Important terminology

d1 receptor dopamine receptors selective clinical agonists drd1 bp gene human d5 chr band agonist selectivity d2 d1-like also dihydrexidine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dopamine receptor D1AliasesDRD1, dopamine receptor D1, DADR, DRD1A1.00infobox
Dopamine receptor D1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1OZ51.00infobox
Dopamine receptor D1Band5q35.21.00infobox
Dopamine receptor D1Band13 B1|13 28.4 cM1.00infobox
Dopamine receptor D1Bgeecaudate nucleus1.00infobox
Dopamine receptor D1Bgeenucleus accumbens1.00infobox
Dopamine receptor D1Bgeeputamen1.00infobox
Dopamine receptor D1Bgeegonad1.00infobox
Dopamine receptor D1Bgeeprefrontal cortex1.00infobox
Dopamine receptor D1BgeeBrodmann area 91.00infobox
Dopamine receptor D1Bgeecingulate gyrus1.00infobox
Dopamine receptor D1Bgeeanterior cingulate cortex1.00infobox
Dopamine receptor D1Bgeeright frontal lobe1.00infobox
Dopamine receptor D1BgeeBrodmann area 461.00infobox
Dopamine receptor D1Bgeedorsal striatum1.00infobox
Dopamine receptor D1Bgeeolfactory tubercle1.00infobox
Dopamine receptor D1Bgeeglobus pallidus1.00infobox
Dopamine receptor D1Bgeesuperior frontal gyrus1.00infobox
Dopamine receptor D1Bgeetemporal lobe1.00infobox
Dopamine receptor D1Bgeeamygdala1.00infobox
Dopamine receptor D1Bgeeneural layer of retina1.00infobox
Dopamine receptor D1Bgeeurethra1.00infobox
Dopamine receptor D1Bgeelumbar subsegment of spinal cord1.00infobox
Dopamine receptor D1BioGPSMore reference expression data1.00infobox
Dopamine receptor D1Chr.Chromosome 5 (human)1.00infobox
Dopamine receptor D1Chr.Chromosome 13 (mouse)1.00infobox
Dopamine receptor D1DatabasesNCBI: entry; OMA: entry1.00infobox
Dopamine receptor D1End175,444,182 bp1.00infobox
Dopamine receptor D1End54,209,724 bp1.00infobox
Dopamine receptor D1EnsemblENSG000001848451.00infobox

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