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Harmine: History, Applications & Research
Harmine, also known as banisterine or telepathine, as well as 7-methoxyharman or 7-methoxy-1-methyl-β-carboline, is a β-carboline and a harmala alkaloid which has hallucinogenic effects and monoamine oxidase inhibitor (MAOI) activity. It occurs in a number of different plants, most notably Peganum harmala and Banisteriopsis caapi. Harmine reversibly…
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Harmine topic overview
The analysis highlights History, Applications and Research as prominent areas in the source structure around Harmine.
Related topics
146
Source areas
7
Connected nodes
153
Extracted relationships
135
Concept neighborhoods
35
Bridge connections
153
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Use and effects · 40 topics
Pharmacology · 37 topics
Overview · 32 topics
Natural occurrence · 18 topics
Chemistry · 7 topics
History · 6 topics
Research · 6 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
3D model (JSmol)
Interactive image
ATC code
None
CAS Number
442-51-3 Y
ChEBI
CHEBI:28121 Y
ChEMBL
ChEMBL269538 Y
ChemSpider
4444445 Y
Explore all related topics Closing gaps
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
How Harmine connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around Harmine shows recurring relationship patterns in the source. For example, Harmine → Banisteriopsis, Barriga Villalba, Bogotá, Colombian, Elger, Fischer-Cárdenas, Fr, Fritzsche, Guillermo Fischer-Cárdenas, Göbel, He, Hoffmann-La Roche, In, Lewin, Louis Lewin, Manchester, Peganum, Professor Robert Robinson, Rafael Zerda-Bayón, Richard Manske Another extracted example is Harmine → Conversely, D2, DAT, DYRK1A, GABAA, However, HT1A, HT2A, HT2C, I2, IC50, IC50Tooltip, In, It, Ki, LSD, MAO-A, MAO-B, PI, The. Use these groups to spot repeated connection types before inspecting the individual relationships.
Harmine
Top relations
related to history· 26
Harmine → Banisteriopsis, Barriga Villalba, Bogotá, Colombian, Elger, Fischer-Cárdenas, Fr, Fritzsche, Guillermo Fischer-Cárdenas, Göbel, He, Hoffmann-La Roche, In, Lewin, Louis Lewin, Manchester, Peganum, Professor Robert Robinson, Rafael Zerda-Bayón, Richard Manske
related to Pharmacodynamics· 21
Harmine → Conversely, D2, DAT, DYRK1A, GABAA, However, HT1A, HT2A, HT2C, I2, IC50, IC50Tooltip, In, It, Ki, LSD, MAO-A, MAO-B, PI, The
related to Biosynthesis· 18
Harmine → AADC, C-2, Decarboxylation, However, Hydroxylation, II, III, In, IV, L-amino, L-tryptophan, Mannich-type, O-methylation, Peganum, Rearrangements, Schiff, The, The Shikimate
related to Monoamine oxidase inhibitor· 16
Harmine → Banisteriopsis, DMT, Doses, However, MAO-A, MAO-B, MAOI, MAOIs, Medically, Oral, Psychotria, RIMA, Syrian, The, These, This
related to Hallucinogen· 7
Harmine → Along, Banisteriopsis, However, In, LSD, The, These
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 135 structured relationships around Harmine. Examples in this analysis include Harmine → 3D model (JSmol) → Interactive image and Harmine → ATC code → None. The table shows each extracted connection, where it came from and its confidence.
Subject
Predicate
Object
Confidence
Src
Harmine
3D model (JSmol)
Interactive image
1.00
infobox
Harmine
ATC code
None
1.00
infobox
Harmine
CAS Number
442-51-3 Y
1.00
infobox
Harmine
ChEBI
CHEBI:28121 Y
1.00
infobox
Harmine
ChEMBL
ChEMBL269538 Y
1.00
infobox
Harmine
ChemSpider
4444445 Y
1.00
infobox
Harmine
CompTox Dashboard (EPA)
DTXSID30196066
1.00
infobox
Harmine
Density
1.326 g/cm3 g/cm3
1.00
infobox
Harmine
Drug class
Hallucinogen; Oneirogen; Reversible inhibitor of monoamine oxidase A
Concept neighborhoods group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around Harmine bring nearby vocabulary together. In this analysis, examples include Caapi, Effects and Found. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Harmine
Caapi
Effects
Found
Serotonin
Biosynthesis
Doses
Tryptamine
Mg
First
Inhibitor
Monoamine
Oral
harmine
Caapi
Effects
Found
Serotonin
Biosynthesis
Doses
Tryptamine
Mg
First
Inhibitor
Monoamine
Oral
harmala alkaloid
Peganum
Β-carboline
Plants
Precursor
Biosynthesis
Banisteriopsis
Isolated
Tryptamine
Serotonin
Caapi
Names
Activity
peganum harmala
Peganum
Plants
Β-carboline
Banisteriopsis
Isolated
Precursor
Biosynthesis
Caapi
Names
Tryptamine
Serotonin
First
biosynthesis
Precursor
Tryptamine
L-tryptophan
Serotonin
Β-carboline
Harmala
Names
Orally
Used
Drug
First
However
side effects
Mg
Hallucinogenic
Doses
Orally
Include
Telepathine
Harmine
Inhibitor
Monoamine
Oral
Oxidase
Found
use and effects
Mg
Hallucinogenic
Doses
Orally
Include
Telepathine
Harmine
Inhibitor
Monoamine
Oral
Oxidase
Found
β-carboline
Tryptamine
Harmala
Serotonin
Known
Precursor
Biosynthesis
Also
Activity
Drug
However
Inhibitor
Monoamine
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For Harmine, one of the stronger structural bridges in this analysis connects Harmine with Use and effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
Harmine
Nodes154
Edges153
Triples135
Avg. degree1.99
Density0.012987
Components1
Source & methodology
TTTA analyzes the structure around Harmine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
