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p21Cip1 (alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA…
Function, Interactions & Clinical significance
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cell cycle dna human p53 gene damage response inhibitor bp cdk2 activity arrest protein cdkn1a dependent also cyclin-dependent kinase g1
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| P21 | Aliases | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A | 1.00 | infobox |
| P21 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AXC, 2ZVV, 2ZVW, 4RJF, 5E0U | 1.00 | infobox |
| P21 | Band | 6p21.2 | 1.00 | infobox |
| P21 | Band | 17 A3.3|17 15.12 cM | 1.00 | infobox |
| P21 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| P21 | Bgee | gastric mucosa | 1.00 | infobox |
| P21 | Bgee | vena cava | 1.00 | infobox |
| P21 | Bgee | left uterine tube | 1.00 | infobox |
| P21 | Bgee | beta cell | 1.00 | infobox |
| P21 | Bgee | ascending aorta | 1.00 | infobox |
| P21 | Bgee | saphenous vein | 1.00 | infobox |
| P21 | Bgee | popliteal artery | 1.00 | infobox |
| P21 | Bgee | tibial arteries | 1.00 | infobox |
| P21 | Bgee | Descending thoracic aorta | 1.00 | infobox |
| P21 | Bgee | stroma of bone marrow | 1.00 | infobox |
| P21 | Bgee | calvaria | 1.00 | infobox |
| P21 | Bgee | molar | 1.00 | infobox |
| P21 | Bgee | pyloric antrum | 1.00 | infobox |
| P21 | Bgee | lip | 1.00 | infobox |
| P21 | Bgee | esophagus | 1.00 | infobox |
| P21 | Bgee | hair follicle | 1.00 | infobox |
| P21 | Bgee | epithelium of stomach | 1.00 | infobox |
| P21 | Bgee | skin of external ear | 1.00 | infobox |
| P21 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| P21 | BioGPS | More reference expression data | 1.00 | infobox |
| P21 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| P21 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| P21 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| P21 | End | 36,687,339 bp | 1.00 | infobox |
| P21 | End | 29,319,701 bp | 1.00 | infobox |
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