Gene ontology · 40Drosha → DEAD/H-box RNA helicase binding, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, double-stranded RNA binding, endonuclease activity, endoribonuclease activity, focal adhesion, gene silencing, hydrolase activity, lipopolysaccharide binding, metal ion binding, microprocessor complex, miRNA metabolic process, nuclease activity, nucleic acid phosphodiester bond hydrolysis, nucleolus, nucleoplasm, nucleus, plasma membrane, positive regulation of gene expression
Bgee · 20Drosha → anterior pituitary, aortic valve, ascending aorta, Brodmann area 23, condyle, endothelial cell, epithelium of colon, fossa, ganglionic eminence, germinal epithelium, middle temporal gyrus, otolith organ, Paneth cell, primitive streak, right hemisphere of cerebellum, Rostral migratory stream, substantia nigra, sural nerve, utricle, ventricular zone
RNA expression pattern · 20Drosha → anterior pituitary, aortic valve, ascending aorta, Brodmann area 23, condyle, endothelial cell, epithelium of colon, fossa, ganglionic eminence, germinal epithelium, middle temporal gyrus, otolith organ, Paneth cell, primitive streak, right hemisphere of cerebellum, Rostral migratory stream, substantia nigra, sural nerve, utricle, ventricular zone
related to Function · 17Drosha → DGCR8, EWSR1, EXP5, FUS, III, Members, Microprocessor, MicroRNA, Pasha, Pre-miRNAs, RISC, RNA, RNA-induced, RNA-specific, The, The Drosha, The RNase III Drosha
related to Clinical significance · 10Drosha → Both Drosha, Dicer, HIV-1, HIV-1-infected, However, PBMCs, The, The Cancer Genome Atlas, This, Thus
related to history · 7Drosha → Argonaute, Dicer, HIV-1, Human Drosha, Recently, RNA, The
Band · 2Drosha → 15|15 A1, 5p13.3
Chr. · 2Drosha → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2Drosha → 12,935,377 bp, 31,532,196 bp
is a · 2Drosha → Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA, core nuclease that executes the initiation step of microRNA
