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Adipogenesis

Adipogenesis is the formation of adipocytes (fat cells) from stem cells. It involves two phases, determination, and terminal differentiation. Determination is mesenchymal stem cells committing to the adipocyte precursor cells, also known as lipoblasts or preadipocytes which lose the potential to differentiate to other types of cells such as chondrocytes…

Other regulations, Introduction & Differentiation

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Overview

Introduction

Differentiation

Transcriptional regulations

Other regulations

Advanced semantic analysis

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Map overview Semantic statistics

Adipogenesis

Nodes45
Edges44
Triples75
Avg. degree1.96
Density0.044444
Components1

How this topic connects Entity context

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Adipogenesis

Top relations

related to PPARγ · 14
Adipogenesis → C/EBPs, DNA, ES, KLFs, Krüppel-like, Moreover, Other, PEPCK, PPARg, PPARγ, RXR, The, Thiazolidinediones, TZDs
related to Introduction · 12
Adipogenesis → ACTH, Adipocytes, C/EBPs, CCAAT, Cellular, Comparing, PPARγ, The, Therefore, This, TNF-alpha, Transcription
related to Transcriptional cascade · 12
Adipogenesis → ADD1, Adipocyte, Although PPARγ, C/EBPα, C/EBPβ, C/EBPδ, GATA2/3, PPARγ, SMAD6/7, SREBP1, T-cell, TCF/LEF
related to C/EBPs · 8
Adipogenesis → At, C/EBPs, C/EBPα, C/EBPβ, C/EBPγ, C/EBPδ, However, PPARγ
related to Epigenetic regulation: TET1 · 5
Adipogenesis → DNA, During, In, TET1, This
related to Insulin and IGF1 · 3
Adipogenesis → IGF1, Insulin, Insulin/IGF1
related to Wnt signaling · 3
Adipogenesis → C/EBPα, PPARγ, Wnt/β-catenin
is a · 2
Adipogenesis → formation of adipocytes, tightly regulated cellular differentiation process
related to Other regulations · 2
Adipogenesis → IGF-1, Products
related to Senescent cells · 2
Adipogenesis → Reduced, Senescent

Important terminology Word statistics

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Important terminology

pparγ differentiation adipocytes cells preadipocytes insulin adipocyte expression factors transcription genes ebpα stem vitro process receptor growth also mature determination

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Adipogenesisis aformation of adipocytes0.90text
Adipogenesisis atightly regulated cellular differentiation process0.90text
chondrocytesinstance ofalso known as lipoblasts or preadipocytes which lose the potential to differentiate to other types of cells0.80text
myocytesinstance ofalso known as lipoblasts or preadipocytes which lose the potential to differentiate to other types of cells0.80text
and osteoblastsinstance ofalso known as lipoblasts or preadipocytes which lose the potential to differentiate to other types of cells0.80text
morphological changesinstance ofPPARg activation has effects on several aspects of the mature adipocyte characteristics0.80text
lipid accumulationinstance ofPPARg activation has effects on several aspects of the mature adipocyte characteristics0.80text
and the acquisition of insulin sensitivityinstance ofPPARg activation has effects on several aspects of the mature adipocyte characteristics0.80text
insulininstance ofOther regulationsProducts of endocrine system0.80text
IGF-1instance ofOther regulationsProducts of endocrine system0.80text
cAMPinstance ofOther regulationsProducts of endocrine system0.80text
glucocorticoidinstance ofOther regulationsProducts of endocrine system0.80text

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