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HMGA is a family of high mobility group proteins characterized by an AT-hook. They code for a "small, nonhistone, chromatin-associated protein that has no intrinsic transcriptional activity but can modulate transcription by altering the chromatin architecture". Mammals have two orthologs: HMGA1 and HMGA2.
The analysis highlights Function, Genomic distribution and Overview as prominent areas in the source structure around HMGA.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around HMGA shows recurring relationship patterns in the source. For example, HMGA → DNA, HMGA1, HMGA2, Normally, O-methylguanine, Thus Another extracted example is HMGA → AT-hook, AT-rich, DNA. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
hmga1 hmga2 proteins dna p21 at-hook cells damage transcriptional activity chromatin chr function association apoptosis domains family high mobility group
TTTA extracted 23 structured relationships around HMGA. Examples in this analysis include HMGA → Alt. symbols → HMGIY and HMGA → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HMGA | Alt. symbols | HMGIY | 1.00 | infobox |
| HMGA | Domains | InterPro | 1.00 | infobox |
| HMGA | HGNC | 5010 | 1.00 | infobox |
| HMGA | Locus | Chr. 6 p21 | 1.00 | infobox |
| HMGA | NCBI gene | 3159 | 1.00 | infobox |
| HMGA | OMIM | 600701 | 1.00 | infobox |
| HMGA | RefSeq | NM_145901 | 1.00 | infobox |
| HMGA | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| HMGA | Structures | Swiss-model | 1.00 | infobox |
| HMGA | Symbol | HMGA1 | 1.00 | infobox |
| HMGA | UniProt | P17096 | 1.00 | infobox |
| HMGA | is a | family of high mobility group proteins characterized by an AT-hook | 0.90 | text |
The concept neighborhoods around HMGA bring nearby vocabulary together. In this analysis, examples include At-hook, Proteins and Characterized. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For HMGA, one of the stronger structural bridges in this analysis connects HMGA with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around HMGA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Genomic distribution & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — HMGA · EN edition · Analysis: TopicsToTalkAbout
