MiR-155

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MiR-155 topic overview

The analysis highlights Physiological roles, Clinical significance and Biogenesis as prominent areas in the source structure around MiR-155.

Related topics: 133
Source areas: 9
Connected nodes: 142
Extracted relationships: 169
Related term clusters: 26
Bridge connections: 142

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Physiological roles · 33 topics

Clinical significance · 21 topics

Biogenesis · 17 topics

Overview · 17 topics

Targets · 16 topics

Tissue distribution · 12 topics

Activity and phenotypes · 8 topics

Discovery · 8 topics

Evolutionary conservation · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domain: Eukaryota;
miRBase family: MIPF0000157
PDB structures: PDBe
Rfam: RF00731
RNA type: microRNA
Symbol: miR-155

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

MiR-155

9MicroRNA · Gene · Physiology

8B-cell · Lymphomas · RNA polymerase II

7Open reading frame · Stem loop · NcRNA

11Exportin-5 · Dicer · Argonaute

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Biogenesis

Evolutionary conservation

Phylogenetic

Tissue distribution

Targets

Activity and phenotypes

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How MiR-155 connects Entity context

The extracted context around MiR-155 shows recurring relationship patterns in the source. For example, MiR-155 → AP-1, Besides, DCs, Downstream, Furthermore, I/JNK/NF-κB, IFN-β, Importantly, Indeed, INPP5D, LPS, MIR155HG, NF-κB, NF-κB-mediated, PAMPs, Raw264, SHIP1, Since, SOCS1, Support Another extracted example is MiR-155 → Additionally, B-cells, B-lymphoid/T-lymphoid, CD34, CLP, CLPs, CMP, CMPs, Finally, Given, Hematopoiesis, HOXA9, HSPCs, Hu, IL-2, MIR155HG, PU, SOCS1, SPI1, T-cell. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Immune system · 27

MiR-155 → AP-1, Besides, DCs, Downstream, Furthermore, I/JNK/NF-κB, IFN-β, Importantly, Indeed, INPP5D, LPS, MIR155HG, NF-κB, NF-κB-mediated, PAMPs, Raw264, SHIP1, Since, SOCS1, Support

related to Hematopoiesis · 24

MiR-155 → Additionally, B-cells, B-lymphoid/T-lymphoid, CD34, CLP, CLPs, CMP, CMPs, Finally, Given, Hematopoiesis, HOXA9, HSPCs, Hu, IL-2, MIR155HG, PU, SOCS1, SPI1, T-cell

related to Targets · 23

MiR-155 → AICDA, Although, BACH1, Bioinformatic, CEBPβ, ETS1, FADD, Figures, IKBKE, IL17RB, INPP5D, IRAK3, JARID2, June, MYD88, PCCD4, RIPK1, SHIP-1, SOCS, SPI1

related to Biogenesis · 15

MiR-155 → Ago, Argonaute, DGCR8, Dicer, DiGeorge, Drosha, Figure, Following, Following Dicer, ORF, RISC, RNA, RNA-induced, RNase III, The MIR155HG RNA

related to Tissue distribution · 11

MiR-155 → Additionally, Although, B-cells, Even, Landgraf, Northern, PCR, RNA, Sequence, T-cells, Together

related to Cancer · 9

MiR-155 → DNA Mismatch Repair, HNPCC, Inactivation, LS, Lynch Syndrome, MMR, Over-silencing, TP53INP1, Tumour Protein-53-induced-nuclear-protein1

related to DNA viruses · 9

MiR-155 → EBV, EBV-infected, Humans-Epstein-Barr Virus, In DNA, K12-11, Kaposi's-sarcoma-associated Herpesvirus, MDV-1, MDV-2, Viruses

related to Cardiovascular · 8

MiR-155 → AT1R, Defective, Furthermore, II, II-related, SNP, Transfection, UTR

related to Activity and phenotypes · 6

MiR-155 → Activation-Induced Cytidine Deaminase, AID, AID-mediated, B-lymphocyte, Cell, Protective

related to Discovery · 6

MiR-155 → B-cell, B-cell Integration Cluster, BIC, II, RNA, The MIR155HG

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

expression mir-155-5p cells mir155hg mirna rna also human may mrna target found role inflammation pre-mir-155 conserved protein levels macrophages immune

MiR-155 relationships Subject–Predicate–Object triples

TTTA extracted 169 structured relationships around MiR-155. Examples in this analysis include MiR-155 → Domain → Eukaryota; and MiR-155 → miRBase family → MIPF0000157. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
MiR-155	Domain	Eukaryota;	1.00	infobox
MiR-155	miRBase family	MIPF0000157	1.00	infobox
MiR-155	PDB structures	PDBe	1.00	infobox
MiR-155	Rfam	RF00731	1.00	infobox
MiR-155	RNA type	microRNA	1.00	infobox
MiR-155	Symbol	miR-155	1.00	infobox
MiR-155	is a	microRNA that in humans is encoded by the MIR155 host gene or MIR155HG	0.90	text
Toll-like receptors	instance of	by pattern recognition receptors	0.80	text
TLR3 ligand poly	instance of	Support for a role of AP-1 in MIR155HG activation comes from studies using stimuli relevant to viral infection	0.80	text
TNF-α involve macrophages with components that include miR-155. miR-155 is overexpressed in atopic dermatitis	instance of	a protein that was found to be involved in B Cell malignancies and to be controlled by miR-155.InflammationInflammatory responses to triggers	0.80	text
contributes to chronic skin inflammation by increasing the proliferative response of T	instance of	a protein that was found to be involved in B Cell malignancies and to be controlled by miR-155.InflammationInflammatory responses to triggers	0.80	text
rheumatoid arthritis	instance of	In Autoimmune disorders	0.80	text

Related concept clusters Related term clusters

The concept neighborhoods around MiR-155 bring nearby vocabulary together. In this analysis, examples include Expression, Cells and Target. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

MiR-155
- Expression
- Cells
- Target
- Protein
- Also
- Cancer
- Immune
- Levels
- Inflammation
- Cardiovascular
- At1r
- Growth
mir-155
- Expression
- Cells
- Target
- Protein
- Also
- Cancer
- Immune
- Levels
- Inflammation
- Cardiovascular
- At1r
- Growth
plasmacytoid dendritic cells
- Expression
- Mir-155
- Mir-155-5p
- Mirna
- Macrophages
- Cell
- Levels
- Found
- Differentiation
- Hematopoiesis
- Including
- Protein
hematopoietic stem-progenitor cells
- Expression
- Mir-155
- Mir-155-5p
- Mirna
- Macrophages
- Cell
- Levels
- Found
- Differentiation
- Hematopoiesis
- Including
- Protein
dendritic cells
- Expression
- Mir-155
- Mir-155-5p
- Mirna
- Macrophages
- Cell
- Levels
- Found
- Differentiation
- Hematopoiesis
- Including
- Protein
expression profiles
- Cells
- Mir-155
- May
- Mir-155-5p
- Mir155hg
- Mirna
- Also
- Growth
- Viral
- Activated
- Including
- Levels
gene
- Mir155hg
- May
- Cardiovascular
- Cancer
- Hematopoiesis
- Sequence
- Targets
- Viral
- Activated
- Activation
- Macrophages
- Cell
cardiovascular
- Cancer
- Inflammation
- Also
- At1r
- Differentiation
- Gene
- Growth
- Hematopoiesis
- Sequence
- Targets
- Viral
- Activated

Connections between topic areas Semantic bridges

For MiR-155, one of the stronger structural bridges in this analysis connects MiR-155 with Physiological roles. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

MiR-155 — Physiological roles · splits 109 ⟂ 34

MiR-155 — Clinical significance · splits 121 ⟂ 22

MiR-155 — Overview · splits 125 ⟂ 18

MiR-155 — Biogenesis · splits 125 ⟂ 18

MiR-155 — Targets · splits 126 ⟂ 17

MiR-155 — Tissue distribution · splits 130 ⟂ 13

MiR-155 — Discovery · splits 134 ⟂ 9

MiR-155 — Activity and phenotypes · splits 134 ⟂ 9

Map overview Semantic statistics

MiR-155

Nodes143

Edges142

Triples169

Avg. degree1.99

Density0.013986

Components1

Source & methodology

TTTA analyzes the structure around MiR-155 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Physiological roles, Clinical significance & Biogenesis, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MiR-155 · EN edition · Analysis: TopicsToTalkAbout

MiR-155: Physiological roles, Clinical significance & Biogenesis

MiR-155 topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Discovery

Biogenesis

Evolutionary conservation

Tissue distribution

Targets

Physiological roles

Activity and phenotypes

Clinical significance

For the semantics nerds

Advanced semantic analysis

How MiR-155 connects Entity context

MiR-155

Top relations

Important terminology

Important terminology

MiR-155 relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

MiR-155

Source & methodology