Histone

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Map view:

Zoom: 100%

More settings

Connection length 100% Label size 100% Node size 100% Line width 100% Label width 100%

Export map as:

Histone topic overview

The analysis highlights History and Measurement as prominent areas in the source structure around Histone.

Related topics: 152
Source areas: 9
Connected nodes: 162
Extracted relationships: 140
Related term clusters: 48
Bridge connections: 162

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 51 topics

Structure · 25 topics

Modification · 24 topics

Classes and variants · 19 topics

Histone chaperones · 11 topics

Evolution and species distribution · 9 topics

History · 9 topics

Synthesis · 3 topics

Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

Histone

17Biology · Base (chemistry) · Protein

18Protein dimer · Tetrameric protein · Electrostatic

11Posttranslational modification · Covalent · Phosphorylation

6Cigarette · Nicotine · Nucleus accumbens

7Symmetry · Tertiary structure · Point groups in three dimensions

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Classes and variants

Evolution and species distribution

Function

Genome

Histone chaperones

Synthesis

History

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Histone connects Entity context

The extracted context around Histone shows recurring relationship patterns in the source. For example, Histone → Albrecht Kossel, Ancient Greek, Biology, Bonner, DNA, Emil Smith, German, Histone Chemistry, Histone IV, Histones, Huang, James, James Bonner, Paul T'so, RNA, Ru Chih, UCLA, World Congress Another extracted example is Histone → AAA, Archaeal, ATPase, C-domain, Clp/Hsp100, Core, Despite, DNA, H1, HC1/HC2, HSH, It's, N-terminal, RPS6/RPS15, Unlike. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to history · 18

Histone → Albrecht Kossel, Ancient Greek, Biology, Bonner, DNA, Emil Smith, German, Histone Chemistry, Histone IV, Histones, Huang, James, James Bonner, Paul T'so, RNA, Ru Chih, UCLA, World Congress

related to Evolution and species distribution · 15

Histone → AAA, Archaeal, ATPase, C-domain, Clp/Hsp100, Core, Despite, DNA, H1, HC1/HC2, HSH, It's, N-terminal, RPS6/RPS15, Unlike

related to Classes and variants · 12

Histone → Angstroms, Around, DNA, Five, H1, H1/H5, H2A, H2B, H3, H4, Higher-order, Histones H2A

related to Beyond eukaryotes · 11

Histone → Additional, Archaeal, Bioinformatic, DNA, DNA-contacting, H3-H4-like, H3/H4-like, MD, Methanothermus, Molecular, Thermococcus

related to Modification · 10

Histone → ADP-ribosylation, Combinations, DNA, H2A, H2B, H4, Histones, Modifications, SUMOylation, The H3

related to Structure · 10

Histone → C2, DNA, DNA-binding, H2A, H2A-H2B, H2B, H3, H3-H4, H4, The H2A-H2B

related to Yeast · 8

Histone → Cdc8, G1, G1/S Cdk, Hir, SBF, Suppression, Whi5, Yeast

related to Addiction · 7

Histone → Cigarette, Delta FosB, Epigenetic, FosB, H3, H4, US

related to Histone chaperones · 7

Histone → ASF1, DNA, During DNA, FACT, Moreover, One, Unlike

related to Chaperone networks · 5

Histone → ASF1, Chaperone, Chromatin, DNA, FACT

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

histones dna chromatin transcription also proteins h3 lysine gene genes methylation chaperones core modifications nucleosome structure acetylation nucleosomes h2a cells

Histone relationships Subject–Predicate–Object triples

TTTA extracted 140 structured relationships around Histone. Examples in this analysis include transcription factors interact with the nucleosomes → instance of → Methylation can affect how other proteins and H2A.X are phosphorylated at sites of DNA damage → instance of → Variants. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
transcription factors interact with the nucleosomes	instance of	Methylation can affect how other proteins	0.80	text
H2A.X are phosphorylated at sites of DNA damage	instance of	Variants	0.80	text
marking regions for recruitment of repair proteins	instance of	Variants	0.80	text
gene regulation	instance of	Histone modifications act in diverse biological processes	0.80	text
DNA repair	instance of	Histone modifications act in diverse biological processes	0.80	text
chromosome condensation	instance of	Histone modifications act in diverse biological processes	0.80	text
neurons	instance of	happens in serotonergic cells	0.80	text
BRCT have been characterised.Effects on transcriptionHistone modifications are involved in control of transcription.Actively transcribed genesTwo histone modifications are particularly associated with active transcription	instance of	and binding domains	0.80	text
histone deacetylases	instance of	which in turn recruits further repressive activities including histone modifiers	0.80	text
histone methyltransferases	instance of	which in turn recruits further repressive activities including histone modifiers	0.80	text
the ultraviolet radiation of the sun.Phosphorylation of H2AX at serine 139	instance of	DNA would get destroyed by damage accumulated from sources	0.80	text
BRCT have been characterised	instance of	and binding domains	0.80	text

Related concept clusters Related term clusters

The concept neighborhoods around Histone bring nearby vocabulary together. In this analysis, examples include Chaperones, Genes and Modifications. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Histone
- Chaperones
- Genes
- Modifications
- Proteins
- Histones
- Variants
- Lysine
- Transcription
- One
- Structure
- Associated
- Two
histone
- Chaperones
- Genes
- Modifications
- Proteins
- Histones
- Variants
- Lysine
- Transcription
- One
- Structure
- Associated
- Two
lysine
- Methylation
- Acetylation
- H3
- Protein
- Known
- Modification
- One
- Proteins
- Histone
- H2b
- H4
- Two
arginine
- Lysine
- Methylation
- H2b
- H4
- Acetylation
- Proteins
- Also
- H3
- Eukaryotic
- Cell
- Damage
- H1
dna
- Histones
- Repair
- Damage
- Nucleosome
- Histone
- Proteins
- Chaperones
- Chromatin
- Modifications
- Transcription
- H2a
- Variants
chromatin
- Chaperones
- Structure
- Histone
- Histones
- Dna
- Gene
- Expression
- H1
- Nucleosomes
- H2a
- Variants
- One
dna damage
- Repair
- Histones
- Chaperones
- Damage
- Dna
- Nucleosome
- Histone
- H2a
- Variants
- Proteins
- Chromatin
- Modifications
gene regulation
- Expression
- Transcription
- Histone
- Histones
- Associated
- Proteins
- Two
- Also
- Cells
- One
- Nucleosome
- Genes

Connections between topic areas Semantic bridges

For Histone, one of the stronger structural bridges in this analysis connects Histone with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Histone — Overview · splits 110 ⟂ 53

Histone — Structure · splits 137 ⟂ 26

Histone — Modification · splits 138 ⟂ 25

Histone — Classes and variants · splits 143 ⟂ 20

Histone — Histone chaperones · splits 151 ⟂ 12

Histone — Evolution and species distribution · splits 153 ⟂ 10

Histone — History · splits 153 ⟂ 10

Histone — Synthesis · splits 159 ⟂ 4

Map overview Semantic statistics

Histone

Nodes163

Edges162

Triples140

Avg. degree1.99

Density0.01227

Components1

Source & methodology

TTTA analyzes the structure around Histone to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Histone · EN edition · Analysis: TopicsToTalkAbout

Histone: History & Measurement

Histone topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

Classes and variants

Structure

Evolution and species distribution

Function

Modification

Histone chaperones

Synthesis

History

For the semantics nerds

Advanced semantic analysis

How Histone connects Entity context

Histone

Top relations

Important terminology

Important terminology

Histone relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

Histone

Source & methodology