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Ribonuclease: Classification, Function & RNase contamination during RNA extraction

Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic enzymes) and 3.1 (for the hydrolytic enzymes) classes of enzymes.

Language: English [EN]
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Ribonuclease topic overview

The analysis highlights Classification, Function and RNase contamination during RNA extraction as prominent areas in the source structure around Ribonuclease.

Related topics
60
Source areas
5
Connected nodes
65
Extracted relationships
82
Concept neighborhoods
35
Bridge connections
65

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Classification · 31 topics
Function · 19 topics
Overview · 6 topics
RNase contamination during RNA extraction · 3 topics
RNase specificity · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR000026 · PF00545
Available protein structures:
IPR000026 · PF00545
InterPro
IPR000026
PDB
1mgwA:56-137 1mgrA:56-137 1uckB:11-92 1i70A:11-92 2sarA:11-92 1ucjB:11-92 1lniB:11-92 1ay7A:11-92 1t2hB:11-92 1boxA:11-92 1uclA:11-92 1rgeB:11-92 1t2iA:11-92 1c54A:11-92 1rsnB:1…
Pfam
PF00545
SCOP2
1brn / SCOPe / SUPFAM

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Classification

RNase specificity

RNase contamination during RNA extraction

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ribonuclease connects Entity context

The extracted context around Ribonuclease shows recurring relationship patterns in the source. For example, Ribonuclease → As, Dicer, DNA, DNA/RNA, EC, EC3, EC4, In, It, One, PDB, RecA/LexA, RNA, RNAs, RNase, RNase III, RNase PhyM, RNase T1, RNase T2, RNase U2 Another extracted example is Ribonuclease → EC, EC2, EC3, Exoribonuclease, Exoribonuclease II, Oligoribonuclease, PNPase, Polynucleotide Phosphorylase, RNA, RNAs, RNase, RNase II, RNase PH. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ribonuclease

Top relations

related to Major types of endoribonucleases · 21
Ribonuclease → As, Dicer, DNA, DNA/RNA, EC, EC3, EC4, In, It, One, PDB, RecA/LexA, RNA, RNAs, RNase, RNase III, RNase PhyM, RNase T1, RNase T2, RNase U2
related to Major types of exoribonucleases · 13
Ribonuclease → EC, EC2, EC3, Exoribonuclease, Exoribonuclease II, Oligoribonuclease, PNPase, Polynucleotide Phosphorylase, RNA, RNAs, RNase, RNase II, RNase PH
related to Sources · 13
Ribonuclease → Academic Press, Christensen SK, D'Alessio, Functions, Gerdes, Lobner-Olesen, Microbiol, Nat, Prokaryotic, Rev, Ribonucleases, Riordan JF, Structures
related to Function · 11
Ribonuclease → All, EndoU-like RNases, Ribonucleases, RNA, RNAs, RNase, RNases, RNP, Some, T1, While
related to RNase contamination during RNA extraction · 8
Ribonuclease → Certain RNases, DNases, For, In, RNA, RNase, RNases, The
related to RNase specificity · 5
Ribonuclease → Although, CRISPR/Cas, DNA, It, The
AlphaFold · 2
Ribonuclease → IPR000026, PF00545
Available protein structures: · 2
Ribonuclease → IPR000026, PF00545
InterPro · 1
Ribonuclease → IPR000026
PDB · 1
Ribonuclease → 1mgwA:56-137 1mgrA:56-137 1uckB:11-92 1i70A:11-92 2sarA:11-92 1ucjB:11-92 1lniB:11-92 1ay7A:11-92 1t2hB:11-92 1boxA:11-92 1uclA:11-92 1rgeB:11-92 1t2iA:11-92 1c54A:11-92 1rsnB:1…

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

rnase rna ec rnases ec3 specific number rnas single-stranded cleaves residues endoribonucleases sequence ribonucleases dna also activity 3'-end 26 functions

Ribonuclease relationships Subject–Predicate–Object triples

TTTA extracted 82 structured relationships around Ribonuclease. Examples in this analysis include Ribonuclease → AlphaFold → IPR000026 and Ribonuclease → AlphaFold → PF00545. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RibonucleaseAlphaFoldIPR0000261.00infobox
RibonucleaseAlphaFoldPF005451.00infobox
RibonucleaseAvailable protein structures:IPR0000261.00infobox
RibonucleaseAvailable protein structures:PF005451.00infobox
RibonucleaseInterProIPR0000261.00infobox
RibonucleasePDB1mgwA:56-137 1mgrA:56-137 1uckB:11-92 1i70A:11-92 2sarA:11-92 1ucjB:11-92 1lniB:11-92 1ay7A:11-92 1t2hB:11-92 1boxA:11-92 1uclA:11-92 1rgeB:11-92 1t2iA:11-92 1c54A:11-92 1rsnB:1…1.00infobox
RibonucleasePfamPF005451.00infobox
RibonucleaseSCOP21brn / SCOPe / SUPFAM1.00infobox
RibonucleaseSymbolRibonuclease1.00infobox
Ainstance ofRNA interference and replication in retroviruses.Some cells also secrete copious quantities of non-specific RNases0.80text
T1instance ofRNA interference and replication in retroviruses.Some cells also secrete copious quantities of non-specific RNases0.80text
Ribonucleaserelated to FunctionRibonucleases0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ribonuclease bring nearby vocabulary together. In this analysis, examples include Type, Rna and Ec3. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ribonuclease
    • Type
    • Rna
    • Ec3
    • Rnase
    • Nuclease
    • Pdb
    • Mechanism
    • Protein
    • Within
    • Cell
    • Dna
    • Well
  • ribonuclease
    • Type
    • Rna
    • Ec3
    • Rnase
    • Nuclease
    • Pdb
    • Mechanism
    • Protein
    • Within
    • Cell
    • Dna
    • Well
  • rna
    • Rnase
    • Ec3
    • Protein
    • Type
    • Ribonucleases
    • Number
    • Specific
    • Rnases
    • Including
    • Mechanism
    • Structures
    • Within
  • rnase a
    • Rna
    • Number
    • Ec3
    • Rnas
    • Ec
    • Specific
    • Ec4
    • Activity
    • Sequence
    • Single-stranded
    • Mechanism
    • Protein
  • noncoding rna
    • Rnase
    • Ec3
    • Protein
    • Type
    • Ribonucleases
    • Number
    • Specific
    • Rnases
    • Including
    • Mechanism
    • Structures
    • Within
  • rna interference
    • Rnase
    • Ec3
    • Protein
    • Type
    • Ribonucleases
    • Number
    • Specific
    • Rnases
    • Including
    • Mechanism
    • Structures
    • Within
  • ribonuclease inhibitor
    • Type
    • Rna
    • Ec3
    • Rnase
    • Nuclease
    • Pdb
    • Mechanism
    • Protein
    • Within
    • Cell
    • Dna
    • Well
  • rnase h
    • Rna
    • Number
    • Ec3
    • Rnas
    • Ec
    • Specific
    • Ec4
    • Activity
    • Sequence
    • Single-stranded
    • Mechanism
    • Protein

Connections between topic areas Semantic bridges

For Ribonuclease, one of the stronger structural bridges in this analysis connects Ribonuclease with Classification. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
RibonucleaseClassification · splits 34 ⟂ 32
RibonucleaseFunction · splits 46 ⟂ 20
RibonucleaseOverview · splits 59 ⟂ 7
RibonucleaseRNase contamination during RNA extraction · splits 62 ⟂ 4

Map overview Semantic statistics

Ribonuclease

Nodes66
Edges65
Triples82
Avg. degree1.97
Density0.030303
Components1

Source & methodology

TTTA analyzes the structure around Ribonuclease to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Classification, Function & RNase contamination during RNA extraction, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ribonuclease · EN edition · Analysis: TopicsToTalkAbout

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