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Elastin: Clinical significance, Composition & Biosynthesis

Elastin is a protein encoded by the ELN gene in humans and several other animals. Elastin is a key component in the extracellular matrix of gnathostomes (jawed vertebrates). It is highly elastic and present in connective tissue of the body to resume its shape after stretching or contracting. Elastin helps skin return to its original position whence poked…

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Elastin topic overview

The analysis highlights Clinical significance, Composition and Biosynthesis as prominent areas in the source structure around Elastin.

Related topics
62
Source areas
6
Connected nodes
68
Extracted relationships
149
Concept neighborhoods
28
Bridge connections
68

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 16 topics
Biosynthesis · 14 topics
Composition · 14 topics
Molecular biology · 7 topics
Overview · 6 topics
Function · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ELN, SVAS, WBS, WS, elastin, ADCL1
Band
7q11.23 · 5 G2|5 74.76 cM
Bgee
Descending thoracic aorta · ascending aorta · right coronary artery · right lung · popliteal artery
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Composition

Biosynthesis

Molecular biology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Elastin connects Entity context

The extracted context around Elastin shows recurring relationship patterns in the source. For example, Elastin → animal organ morphogenesis, aortic valve morphogenesis, blood circulation, cell population proliferation, collagen-containing extracellular matrix, elastic fiber, extracellular matrix, extracellular matrix binding, extracellular matrix constituent conferring elasticity, extracellular matrix disassembly, extracellular matrix organization, extracellular matrix structural constituent, extracellular region, outflow tract morphogenesis, protein binding, regulation of actin filament polymerization, regulation of smooth muscle cell proliferation, respiratory gaseous exchange by respiratory system, skeletal muscle tissue development, stress fiber assembly Another extracted example is Elastin → aortic valve, ascending aorta, atrioventricular valve, Descending thoracic aorta, external carotid artery, gastric mucosa, internal carotid artery, lactiferous gland, left coronary artery, left lung lobe, optic nerve, popliteal artery, right auricle of heart, right coronary artery, right lung, tibial arteries, tunica media of zone of aorta, umbilical cord, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.

Elastin

Top relations

Gene ontology · 20
Elastin → animal organ morphogenesis, aortic valve morphogenesis, blood circulation, cell population proliferation, collagen-containing extracellular matrix, elastic fiber, extracellular matrix, extracellular matrix binding, extracellular matrix constituent conferring elasticity, extracellular matrix disassembly, extracellular matrix organization, extracellular matrix structural constituent, extracellular region, outflow tract morphogenesis, protein binding, regulation of actin filament polymerization, regulation of smooth muscle cell proliferation, respiratory gaseous exchange by respiratory system, skeletal muscle tissue development, stress fiber assembly
Bgee · 19
Elastin → aortic valve, ascending aorta, atrioventricular valve, Descending thoracic aorta, external carotid artery, gastric mucosa, internal carotid artery, lactiferous gland, left coronary artery, left lung lobe, optic nerve, popliteal artery, right auricle of heart, right coronary artery, right lung, tibial arteries, tunica media of zone of aorta, umbilical cord, upper lobe of left lung
RNA expression pattern · 19
Elastin → aortic valve, ascending aorta, atrioventricular valve, Descending thoracic aorta, external carotid artery, gastric mucosa, internal carotid artery, lactiferous gland, left coronary artery, left lung lobe, optic nerve, popliteal artery, right auricle of heart, right coronary artery, right lung, tibial arteries, tunica media of zone of aorta, umbilical cord, upper lobe of left lung
related to External links · 11
Elastin → Boston UniversityGeneReviews/NIH/NCBI/UW, Histology, Histology Learning System, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library, Williams, Williams-Beuren SyndromeThe Elastin ProteinMicrofibril
related to Tropoelastin precursors · 9
Elastin → AAAKAAKAA, Each, In, KA, KP, KPLKP, Lys-Ala, Lys-Pro, The
related to Clinical significance · 8
Elastin → Buschke, Deletions, Marfan, Menkes, Ollendorff, Other, SVAS, Williams
related to Molecular biology · 7
Elastin → ELN, In, SVAS, The, There, These, Tissue
related to Composition · 5
Elastin → Both, Comparison, Elastic, In, The
related to Function · 4
Elastin → Elastin's, Multiple, The, The ELN
related to Aggregation · 3
Elastin → The, This, Tropoelastin

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

tropoelastin gene protein elastic human tissue bp eln domains skin chr band chromosome also extracellular lysine function vertebrates elastosis crosslinking

Elastin relationships Subject–Predicate–Object triples

TTTA extracted 149 structured relationships around Elastin. Examples in this analysis include Elastin → Aliases → ELN, SVAS, WBS, WS, elastin, ADCL1 and Elastin → Band → 7q11.23. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ElastinAliasesELN, SVAS, WBS, WS, elastin, ADCL11.00infobox
ElastinBand7q11.231.00infobox
ElastinBand5 G2|5 74.76 cM1.00infobox
ElastinBgeeDescending thoracic aorta1.00infobox
ElastinBgeeascending aorta1.00infobox
ElastinBgeeright coronary artery1.00infobox
ElastinBgeeright lung1.00infobox
ElastinBgeepopliteal artery1.00infobox
ElastinBgeetibial arteries1.00infobox
ElastinBgeegastric mucosa1.00infobox
ElastinBgeeleft coronary artery1.00infobox
ElastinBgeeright auricle of heart1.00infobox
ElastinBgeeupper lobe of left lung1.00infobox
ElastinBgeeaortic valve1.00infobox
ElastinBgeeleft lung lobe1.00infobox
ElastinBgeeexternal carotid artery1.00infobox
ElastinBgeetunica media of zone of aorta1.00infobox
ElastinBgeeinternal carotid artery1.00infobox
ElastinBgeeoptic nerve1.00infobox
ElastinBgeeumbilical cord1.00infobox
ElastinBgeelactiferous gland1.00infobox
ElastinBgeeatrioventricular valve1.00infobox
ElastinBioGPSn/a1.00infobox
ElastinChr.Chromosome 7 (human)1.00infobox
ElastinChr.Chromosome 5 (mouse)1.00infobox
ElastinDatabasesNCBI: entry; OMA: entry1.00infobox
ElastinEnd74,069,907 bp1.00infobox
ElastinEnd134,776,177 bp1.00infobox
ElastinEnsemblENSG000000495401.00infobox
ElastinEntrez20061.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Elastin bring nearby vocabulary together. In this analysis, examples include Tropoelastin, Elastic and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Elastin
    • Tropoelastin
    • Elastic
    • Protein
    • Tissue
    • Important
    • Also
    • Function
    • Tissues
    • Skin
    • Gene
    • Arteries
    • Associated
  • elastin
    • Tropoelastin
    • Elastic
    • Protein
    • Tissue
    • Important
    • Also
    • Function
    • Tissues
    • Skin
    • Gene
    • Arteries
    • Associated
  • gene
    • Chromosome
    • Location
    • Svas
    • Human
    • Bp
    • Chr
    • Tissue
    • Tropoelastin
    • External
    • Molecular
    • Mouse
    • Protein
  • elastic
    • Function
    • Tissue
    • External
    • Molecular
    • Arteries
    • Body
    • Fiber
    • Important
    • Location
    • Also
    • Elastin
    • Bp
  • elastic fibers
    • Function
    • Tissue
    • External
    • Molecular
    • Arteries
    • Body
    • Fiber
    • Important
    • Location
    • Also
    • Elastin
    • Bp
  • elastic fiber
    • Function
    • Tissue
    • External
    • Molecular
    • Mouse
    • Arteries
    • Body
    • Fiber
    • Human
    • Important
    • Location
    • Also
  • elastic ligaments
    • Function
    • Tissue
    • External
    • Molecular
    • Arteries
    • Body
    • Fiber
    • Important
    • Location
    • Also
    • Elastin
    • Bp
  • elastic cartilage
    • Function
    • Tissue
    • External
    • Molecular
    • Arteries
    • Body
    • Fiber
    • Important
    • Location
    • Also
    • Elastin
    • Bp

Connections between topic areas Semantic bridges

For Elastin, one of the stronger structural bridges in this analysis connects Elastin with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ElastinClinical significance · splits 52 ⟂ 17
ElastinComposition · splits 54 ⟂ 15
ElastinBiosynthesis · splits 54 ⟂ 15
ElastinMolecular biology · splits 61 ⟂ 8
ElastinOverview · splits 62 ⟂ 7
ElastinFunction · splits 63 ⟂ 6

Map overview Semantic statistics

Elastin

Nodes69
Edges68
Triples149
Avg. degree1.97
Density0.028986
Components1

Source & methodology

TTTA analyzes the structure around Elastin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Composition & Biosynthesis, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Elastin · EN edition · Analysis: TopicsToTalkAbout

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