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Elastin

Elastin is a protein encoded by the ELN gene in humans and several other animals. Elastin is a key component in the extracellular matrix of gnathostomes (jawed vertebrates). It is highly elastic and present in connective tissue of the body to resume its shape after stretching or contracting. Elastin helps skin return to its original position whence poked…

Clinical significance, Composition & Biosynthesis

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Aliases
ELN, SVAS, WBS, WS, elastin, ADCL1
Band
7q11.23 · 5 G2|5 74.76 cM
Bgee
Descending thoracic aorta · ascending aorta · right coronary artery · right lung · popliteal artery
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

Composition

Biosynthesis

Molecular biology

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Map overview Semantic statistics

Elastin

Nodes69
Edges68
Triples149
Avg. degree1.97
Density0.028986
Components1

How this topic connects Entity context

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Elastin

Top relations

Gene ontology · 20
Elastin → animal organ morphogenesis, aortic valve morphogenesis, blood circulation, cell population proliferation, collagen-containing extracellular matrix, elastic fiber, extracellular matrix, extracellular matrix binding, extracellular matrix constituent conferring elasticity, extracellular matrix disassembly, extracellular matrix organization, extracellular matrix structural constituent, extracellular region, outflow tract morphogenesis, protein binding, regulation of actin filament polymerization, regulation of smooth muscle cell proliferation, respiratory gaseous exchange by respiratory system, skeletal muscle tissue development, stress fiber assembly
Bgee · 19
Elastin → aortic valve, ascending aorta, atrioventricular valve, Descending thoracic aorta, external carotid artery, gastric mucosa, internal carotid artery, lactiferous gland, left coronary artery, left lung lobe, optic nerve, popliteal artery, right auricle of heart, right coronary artery, right lung, tibial arteries, tunica media of zone of aorta, umbilical cord, upper lobe of left lung
RNA expression pattern · 19
Elastin → aortic valve, ascending aorta, atrioventricular valve, Descending thoracic aorta, external carotid artery, gastric mucosa, internal carotid artery, lactiferous gland, left coronary artery, left lung lobe, optic nerve, popliteal artery, right auricle of heart, right coronary artery, right lung, tibial arteries, tunica media of zone of aorta, umbilical cord, upper lobe of left lung
related to External links · 11
Elastin → Boston UniversityGeneReviews/NIH/NCBI/UW, Histology, Histology Learning System, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library, Williams, Williams-Beuren SyndromeThe Elastin ProteinMicrofibril
related to Tropoelastin precursors · 9
Elastin → AAAKAAKAA, Each, In, KA, KP, KPLKP, Lys-Ala, Lys-Pro, The
related to Clinical significance · 8
Elastin → Buschke, Deletions, Marfan, Menkes, Ollendorff, Other, SVAS, Williams
related to Molecular biology · 7
Elastin → ELN, In, SVAS, The, There, These, Tissue
related to Composition · 5
Elastin → Both, Comparison, Elastic, In, The
related to Function · 4
Elastin → Elastin's, Multiple, The, The ELN
related to Aggregation · 3
Elastin → The, This, Tropoelastin

Important terminology Word statistics

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Important terminology

tropoelastin gene protein elastic human tissue bp eln domains skin chr band chromosome also extracellular lysine function vertebrates elastosis crosslinking

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ElastinAliasesELN, SVAS, WBS, WS, elastin, ADCL11.00infobox
ElastinBand7q11.231.00infobox
ElastinBand5 G2|5 74.76 cM1.00infobox
ElastinBgeeDescending thoracic aorta1.00infobox
ElastinBgeeascending aorta1.00infobox
ElastinBgeeright coronary artery1.00infobox
ElastinBgeeright lung1.00infobox
ElastinBgeepopliteal artery1.00infobox
ElastinBgeetibial arteries1.00infobox
ElastinBgeegastric mucosa1.00infobox
ElastinBgeeleft coronary artery1.00infobox
ElastinBgeeright auricle of heart1.00infobox
ElastinBgeeupper lobe of left lung1.00infobox
ElastinBgeeaortic valve1.00infobox
ElastinBgeeleft lung lobe1.00infobox
ElastinBgeeexternal carotid artery1.00infobox
ElastinBgeetunica media of zone of aorta1.00infobox
ElastinBgeeinternal carotid artery1.00infobox
ElastinBgeeoptic nerve1.00infobox
ElastinBgeeumbilical cord1.00infobox
ElastinBgeelactiferous gland1.00infobox
ElastinBgeeatrioventricular valve1.00infobox
ElastinBioGPSn/a1.00infobox
ElastinChr.Chromosome 7 (human)1.00infobox
ElastinChr.Chromosome 5 (mouse)1.00infobox
ElastinDatabasesNCBI: entry; OMA: entry1.00infobox
ElastinEnd74,069,907 bp1.00infobox
ElastinEnd134,776,177 bp1.00infobox
ElastinEnsemblENSG000000495401.00infobox
ElastinEntrez20061.00infobox

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