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Morpholino nucleic acid

A Morpholino, also known as a phosphorodiamidate Morpholino oligomer (PMO), is a nucleic acid analog whose backbone consists of methylenemorpholine rings linked through phosphorodiamidate groups, in contrast to the sugars linked through phosphates found in natural nucleic acids. Synthetic oligomers of Morpholinos are used in molecular biology to modify…

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Morpholino nucleic acid

Nodes112
Edges111
Triples4
Avg. degree1.98
Density0.017857
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morpholinos morpholino mrna cells gene rna expression used protein acid knockdown nucleic molecules delivery oligos embryos phenotype rescue effects also

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SubjectPredicateObjectConfidenceSrc
bacteria or virusesinstance ofMorpholinos are used as research tools for reverse genetics by knocking down gene function.Morpholinos are in development as pharmaceutical therapeutics targeted against pathoge…0.80text
genetic diseasesinstance ofMorpholinos are used as research tools for reverse genetics by knocking down gene function.Morpholinos are in development as pharmaceutical therapeutics targeted against pathoge…0.80text
splice silencersinstance ofor by interfering with the binding of splice regulatory proteins0.80text
splice enhancersinstance ofor by interfering with the binding of splice regulatory proteins0.80text

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