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CEBPA

CCAAT/enhancer-binding protein alpha is a protein encoded by the CEBPA gene in humans. CCAAT/enhancer-binding protein alpha is a transcription factor involved in the differentiation of certain blood cells. For details on the CCAAT structural motif in gene enhancers and on CCAAT/Enhancer Binding Proteins see the specific page.

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Aliases
CEBPA, C/EBP-alpha, CEBP, CCAAT/enhancer binding protein alpha, CCAAT enhancer binding protein alpha
Band
19q13.11 · 7 B2|7 21.02 cM
Bgee
nipple · skin of arm · human penis · skin of thigh · skin of abdomen
BioGPS
n/a
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Common mutations

Interactions

Clinical significance

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Map overview Semantic statistics

CEBPA

Nodes39
Edges38
Triples174
Avg. degree1.95
Density0.051282
Components1

How this topic connects Entity context

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CEBPA

Top relations

Gene ontology · 63
CEBPA → brown fat cell differentiation, cell maturation, cellular response to lithium ion, cellular response to organic cyclic compound, cellular response to tumor necrosis factor, cholesterol metabolic process, cytokine-mediated signaling pathway, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic placenta development, fat cell differentiation, generation of precursor metabolites and energy, glucose homeostasis, granulocyte differentiation, inner ear development, interleukin-6-mediated signaling pathway, intracellular membrane-bounded organelle, kinase binding
Bgee · 19
CEBPA → adipose tissue, brown adipose tissue, gallbladder, human penis, lactiferous gland, lip, monocyte, nipple, right lobe of liver, right lung, skin of abdomen, skin of arm, skin of external ear, skin of thigh, stroma of bone marrow, subcutaneous adipose tissue, tunica adventitia of aorta, vulva, white adipose tissue
RNA expression pattern · 19
CEBPA → adipose tissue, brown adipose tissue, gallbladder, human penis, lactiferous gland, lip, monocyte, nipple, right lobe of liver, right lung, skin of abdomen, skin of arm, skin of external ear, skin of thigh, stroma of bone marrow, subcutaneous adipose tissue, tunica adventitia of aorta, vulva, white adipose tissue
related to Prognostic significance of CEBPA mutations · 14
CEBPA → AML, C-terminal, CCAAT/enhancer-binding, In, M1, M2, Many, Mutation, N-terminal, Patients, The, Therefore, These, This
related to External links · 12
CEBPA → AML, Familial Acute Myeloid Leukemia, GeneReviews/NIH/NCBI/UW, Human CEBPA, Medicine, Medicine Medical Subject Headings, MeSH, Mutated CEBPACEBPA, National Library, This, UCSC Genome Browser, United States National Library
related to Function · 9
CEBPA → Also, CDK2, CDK4, CEBP-beta, CEBP-gamma, In, It, Jun, The
related to Common mutations · 7
CEBPA → CCAAT/enhancer-binding, COOH-terminal, DNA, NH2, One, The, There
related to Significance in acute myeloid leukemia · 6
CEBPA → Acute, CCAAT/enhancer-binding, CEBPA's, For, It, This
Band · 2
CEBPA → 19q13.11, 7 B2|7 21.02 cM
Chr. · 2
CEBPA → Chromosome 19 (human), Chromosome 7 (mouse)

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Important terminology

myeloid protein gene ccaat mutations acute leukemia alpha enhancer-binding human differentiation bp patients chr band transcription shown encoded binding chromosome

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CEBPAAliasesCEBPA, C/EBP-alpha, CEBP, CCAAT/enhancer binding protein alpha, CCAAT enhancer binding protein alpha1.00infobox
CEBPABand19q13.111.00infobox
CEBPABand7 B2|7 21.02 cM1.00infobox
CEBPABgeenipple1.00infobox
CEBPABgeeskin of arm1.00infobox
CEBPABgeehuman penis1.00infobox
CEBPABgeeskin of thigh1.00infobox
CEBPABgeeskin of abdomen1.00infobox
CEBPABgeeright lobe of liver1.00infobox
CEBPABgeemonocyte1.00infobox
CEBPABgeeadipose tissue1.00infobox
CEBPABgeesubcutaneous adipose tissue1.00infobox
CEBPABgeevulva1.00infobox
CEBPABgeelactiferous gland1.00infobox
CEBPABgeebrown adipose tissue1.00infobox
CEBPABgeewhite adipose tissue1.00infobox
CEBPABgeelip1.00infobox
CEBPABgeetunica adventitia of aorta1.00infobox
CEBPABgeeskin of external ear1.00infobox
CEBPABgeestroma of bone marrow1.00infobox
CEBPABgeeright lung1.00infobox
CEBPABgeegallbladder1.00infobox
CEBPABioGPSn/a1.00infobox
CEBPAChr.Chromosome 19 (human)1.00infobox
CEBPAChr.Chromosome 7 (mouse)1.00infobox
CEBPADatabasesNCBI: entry; OMA: entry1.00infobox
CEBPAEnd33,302,534 bp1.00infobox
CEBPAEnd34,821,353 bp1.00infobox
CEBPAEnsemblENSG000002458481.00infobox
CEBPAEntrez10501.00infobox

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