CEBPA

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CEBPA topic overview

The analysis highlights Function, Clinical significance and Interactions as prominent areas in the source structure around CEBPA.

Related topics: 33
Source areas: 5
Connected nodes: 38
Extracted relationships: 174
Concept neighborhoods: 16
Bridge connections: 38

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 13 topics

Clinical significance · 9 topics

Overview · 7 topics

Interactions · 3 topics

Common mutations · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CEBPA, C/EBP-alpha, CEBP, CCAAT/enhancer binding protein alpha, CCAAT enhancer binding protein alpha
Band: 19q13.11 · 7 B2|7 21.02 cM
Bgee: nipple · skin of arm · human penis · skin of thigh · skin of abdomen
BioGPS: n/a
Chr.: Chromosome 19 (human) · Chromosome 7 (mouse)
Databases: NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Interactions

Clinical significance

Hematopoiesis
Tumor suppressor
Frameshift mutation
Differentiation Cellular differentiation
Downregulation
Head and neck squamous cell carcinoma Head and neck cancer
Methylation
Biomarker
Prognosis

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CEBPA connects Entity context

The extracted context around CEBPA shows recurring relationship patterns in the source. For example, CEBPA → brown fat cell differentiation, cell maturation, cellular response to lithium ion, cellular response to organic cyclic compound, cellular response to tumor necrosis factor, cholesterol metabolic process, cytokine-mediated signaling pathway, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic placenta development, fat cell differentiation, generation of precursor metabolites and energy, glucose homeostasis, granulocyte differentiation, inner ear development, interleukin-6-mediated signaling pathway, intracellular membrane-bounded organelle, kinase binding Another extracted example is CEBPA → adipose tissue, brown adipose tissue, gallbladder, human penis, lactiferous gland, lip, monocyte, nipple, right lobe of liver, right lung, skin of abdomen, skin of arm, skin of external ear, skin of thigh, stroma of bone marrow, subcutaneous adipose tissue, tunica adventitia of aorta, vulva, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 63

CEBPA → brown fat cell differentiation, cell maturation, cellular response to lithium ion, cellular response to organic cyclic compound, cellular response to tumor necrosis factor, cholesterol metabolic process, cytokine-mediated signaling pathway, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic placenta development, fat cell differentiation, generation of precursor metabolites and energy, glucose homeostasis, granulocyte differentiation, inner ear development, interleukin-6-mediated signaling pathway, intracellular membrane-bounded organelle, kinase binding

Bgee · 19

CEBPA → adipose tissue, brown adipose tissue, gallbladder, human penis, lactiferous gland, lip, monocyte, nipple, right lobe of liver, right lung, skin of abdomen, skin of arm, skin of external ear, skin of thigh, stroma of bone marrow, subcutaneous adipose tissue, tunica adventitia of aorta, vulva, white adipose tissue

RNA expression pattern · 19

related to Prognostic significance of CEBPA mutations · 14

CEBPA → AML, C-terminal, CCAAT/enhancer-binding, In, M1, M2, Many, Mutation, N-terminal, Patients, The, Therefore, These, This

related to External links · 12

CEBPA → AML, Familial Acute Myeloid Leukemia, GeneReviews/NIH/NCBI/UW, Human CEBPA, Medicine, Medicine Medical Subject Headings, MeSH, Mutated CEBPACEBPA, National Library, This, UCSC Genome Browser, United States National Library

related to Function · 9

CEBPA → Also, CDK2, CDK4, CEBP-beta, CEBP-gamma, In, It, Jun, The

related to Common mutations · 7

CEBPA → CCAAT/enhancer-binding, COOH-terminal, DNA, NH2, One, The, There

related to Significance in acute myeloid leukemia · 6

CEBPA → Acute, CCAAT/enhancer-binding, CEBPA's, For, It, This

Band · 2

CEBPA → 19q13.11, 7 B2|7 21.02 cM

Chr. · 2

CEBPA → Chromosome 19 (human), Chromosome 7 (mouse)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

myeloid protein gene ccaat mutations acute leukemia alpha enhancer-binding human differentiation bp patients chr band transcription shown encoded binding chromosome

CEBPA relationships Subject–Predicate–Object triples

TTTA extracted 174 structured relationships around CEBPA. Examples in this analysis include CEBPA → Aliases → CEBPA, C/EBP-alpha, CEBP, CCAAT/enhancer binding protein alpha, CCAAT enhancer binding protein alpha and CEBPA → Band → 19q13.11. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
CEBPA	Aliases	CEBPA, C/EBP-alpha, CEBP, CCAAT/enhancer binding protein alpha, CCAAT enhancer binding protein alpha	1.00	infobox
CEBPA	Band	19q13.11	1.00	infobox
CEBPA	Band	7 B2\|7 21.02 cM	1.00	infobox
CEBPA	Bgee	nipple	1.00	infobox
CEBPA	Bgee	skin of arm	1.00	infobox
CEBPA	Bgee	human penis	1.00	infobox
CEBPA	Bgee	skin of thigh	1.00	infobox
CEBPA	Bgee	skin of abdomen	1.00	infobox
CEBPA	Bgee	right lobe of liver	1.00	infobox
CEBPA	Bgee	monocyte	1.00	infobox
CEBPA	Bgee	adipose tissue	1.00	infobox
CEBPA	Bgee	subcutaneous adipose tissue	1.00	infobox
CEBPA	Bgee	vulva	1.00	infobox
CEBPA	Bgee	lactiferous gland	1.00	infobox
CEBPA	Bgee	brown adipose tissue	1.00	infobox
CEBPA	Bgee	white adipose tissue	1.00	infobox
CEBPA	Bgee	lip	1.00	infobox
CEBPA	Bgee	tunica adventitia of aorta	1.00	infobox
CEBPA	Bgee	skin of external ear	1.00	infobox
CEBPA	Bgee	stroma of bone marrow	1.00	infobox
CEBPA	Bgee	right lung	1.00	infobox
CEBPA	Bgee	gallbladder	1.00	infobox
CEBPA	BioGPS	n/a	1.00	infobox
CEBPA	Chr.	Chromosome 19 (human)	1.00	infobox
CEBPA	Chr.	Chromosome 7 (mouse)	1.00	infobox
CEBPA	Databases	NCBI: entry; OMA: entry	1.00	infobox
CEBPA	End	33,302,534 bp	1.00	infobox
CEBPA	End	34,821,353 bp	1.00	infobox
CEBPA	Ensembl	ENSG00000245848	1.00	infobox
CEBPA	Entrez	1050	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CEBPA bring nearby vocabulary together. In this analysis, examples include Myeloid, Acute and Leukemia. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

CEBPA
- Myeloid
- Acute
- Leukemia
- Mutations
- Protein
- Shown
- Patients
- Gene
- Methylation
- Human
- Enhancer-binding
- Response
cebpa
- Myeloid
- Acute
- Leukemia
- Mutations
- Protein
- Shown
- Patients
- Gene
- Methylation
- Human
- Enhancer-binding
- Response
protein
- Myeloid
- Factor
- Important
- Binding
- Expression
- Transcription
- Mutations
- Human
- External
- Function
- Acute
- Leukemia
gene
- Location
- Human
- Enhancer
- Binding
- Chromosome
- Protein
- Bp
- Chr
- External
- Function
- Mouse
- Page
transcription factor
- Factor
- Transcription
- Differentiation
- Encoded
- External
- Function
- Mouse
- Protein
- Alpha
- Enhancer
- Enhancer-binding
- Granulocyte
gene enhancers
- Location
- Human
- Enhancer
- Binding
- Chromosome
- Protein
- Bp
- Chr
- External
- Function
- Mouse
- Page
acute myeloid leukemia
- Leukemia
- Myeloid
- Cebpa
- Patients
- Prognosis
- Protein
- Granulocyte
- Mutations
- Gene
- Shown
- Aml
- Methylation
differentiation
- Factor
- Transcription
- Enhancer-binding
- Protein
- Granulocyte
- Important
- Expression
- Encoded
- Myeloid
- Gene
- External
- Function

Connections between topic areas Semantic bridges

For CEBPA, one of the stronger structural bridges in this analysis connects CEBPA with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

CEBPA — Function · splits 25 ⟂ 14

CEBPA — Clinical significance · splits 29 ⟂ 10

CEBPA — Overview · splits 31 ⟂ 8

CEBPA — Interactions · splits 35 ⟂ 4

Map overview Semantic statistics

CEBPA

Nodes39

Edges38

Triples174

Avg. degree1.95

Density0.051282

Components1

Source & methodology

TTTA analyzes the structure around CEBPA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CEBPA · EN edition · Analysis: TopicsToTalkAbout