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Amitriptyline, formerly sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. Due to the frequency and prominence of side effects, amitriptyline is generally considered a…
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Explore the main themes, entities and connections around Amitriptyline. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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effects may nortriptyline pain patients side drug cyp2d6 used depression cyp2c19 treatment recommended also antidepressant serotonin level metabolizers due however
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Amitriptyline | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Amitriptyline | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Amitriptyline | ATC code | N06AA09 (WHO) | 1.00 | infobox |
| Amitriptyline | Bioavailability | 45–53% | 1.00 | infobox |
| Amitriptyline | CAS Number | 50-48-6 Y 549-18-8 (hydrochloride) 17086-03-2 (embonate) | 1.00 | infobox |
| Amitriptyline | ChEBI | CHEBI:2666 Y | 1.00 | infobox |
| Amitriptyline | ChEMBL | ChEMBL629 Y | 1.00 | infobox |
| Amitriptyline | ChemSpider | 2075 Y | 1.00 | infobox |
| Amitriptyline | CompTox Dashboard (EPA) | DTXSID7022594 | 1.00 | infobox |
| Amitriptyline | Drug class | Tricyclic antidepressant (TCA) | 1.00 | infobox |
| Amitriptyline | DrugBank | DB00321 Y | 1.00 | infobox |
| Amitriptyline | ECHA InfoCard | 100.000.038 | 1.00 | infobox |
| Amitriptyline | Elimination half-life | 21 hours | 1.00 | infobox |
| Amitriptyline | Excretion | Urine: 12–80% after 48 hours; feces: not studied | 1.00 | infobox |
| Amitriptyline | Formula | C20H23N | 1.00 | infobox |
| Amitriptyline | IUPHAR/BPS | 200 | 1.00 | infobox |
| Amitriptyline | KEGG | D07448 Y | 1.00 | infobox |
| Amitriptyline | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Amitriptyline | Legal status | BR: Class C1 (Other controlled substances) | 1.00 | infobox |
| Amitriptyline | Legal status | CA: ℞-only | 1.00 | infobox |
| Amitriptyline | Legal status | UK: POM (Prescription only) | 1.00 | infobox |
| Amitriptyline | Legal status | US: ℞-only | 1.00 | infobox |
| Amitriptyline | License data | US DailyMed: Amitriptyline | 1.00 | infobox |
| Amitriptyline | MedlinePlus | a682388 | 1.00 | infobox |
| Amitriptyline | Melting point | 197.5 °C (387.5 °F) | 1.00 | infobox |
| Amitriptyline | Metabolism | Liver (CYP2D6, CYP2C19, CYP3A4) | 1.00 | infobox |
| Amitriptyline | Metabolites | nortriptyline, (E)-10-hydroxynortriptyline | 1.00 | infobox |
| Amitriptyline | Molar mass | 277.411 g·mol−1 | 1.00 | infobox |
| Amitriptyline | Pregnancy category | AU: C | 1.00 | infobox |
| Amitriptyline | Pronunciation | /ˌæmɪˈtrɪptɪliːn/ | 1.00 | infobox |
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