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Amitriptyline, formerly sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. Due to the frequency and prominence of side effects, amitriptyline is generally considered a…
The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Amitriptyline.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around Amitriptyline shows recurring relationship patterns in the source. For example, Amitriptyline → Amitriptylin, BANM, BANMTooltip British Approved Name, BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, Elavil, Endep, English, French, German, INNTooltip International Nonproprietary Name, Italian, JANTooltip Japanese Accepted Name, Latin, Name, Spanish, Tryptomer, USANTooltip United States Adopted, USPTooltip United States Pharmacopeia Another extracted example is Amitriptyline → American, Ayd, Drug Administration, Following, Frank Ayd, In Europe, Lundbeck, Merck, One, Roche, US Food. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
effects may nortriptyline pain patients side drug cyp2d6 used depression cyp2c19 treatment recommended also antidepressant serotonin level metabolizers due liver
TTTA extracted 140 structured relationships around Amitriptyline. Examples in this analysis include Amitriptyline → 3D model (JSmol) → Interactive image and Amitriptyline → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Amitriptyline | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Amitriptyline | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Amitriptyline | ATC code | N06AA09 (WHO) | 1.00 | infobox |
| Amitriptyline | Bioavailability | 45–53% | 1.00 | infobox |
| Amitriptyline | CAS Number | 50-48-6 Y 549-18-8 (hydrochloride) 17086-03-2 (embonate) | 1.00 | infobox |
| Amitriptyline | ChEBI | CHEBI:2666 Y | 1.00 | infobox |
| Amitriptyline | ChEMBL | ChEMBL629 Y | 1.00 | infobox |
| Amitriptyline | ChemSpider | 2075 Y | 1.00 | infobox |
| Amitriptyline | CompTox Dashboard (EPA) | DTXSID7022594 | 1.00 | infobox |
| Amitriptyline | Drug class | Tricyclic antidepressant (TCA) | 1.00 | infobox |
| Amitriptyline | DrugBank | DB00321 Y | 1.00 | infobox |
| Amitriptyline | ECHA InfoCard | 100.000.038 | 1.00 | infobox |
| Amitriptyline | Elimination half-life | 21 hours | 1.00 | infobox |
| Amitriptyline | Excretion | Urine: 12–80% after 48 hours; feces: not studied | 1.00 | infobox |
| Amitriptyline | Formula | C20H23N | 1.00 | infobox |
| Amitriptyline | IUPHAR/BPS | 200 | 1.00 | infobox |
| Amitriptyline | KEGG | D07448 Y | 1.00 | infobox |
| Amitriptyline | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Amitriptyline | Legal status | BR: Class C1 (Other controlled substances) | 1.00 | infobox |
| Amitriptyline | Legal status | CA: ℞-only | 1.00 | infobox |
| Amitriptyline | Legal status | UK: POM (Prescription only) | 1.00 | infobox |
| Amitriptyline | Legal status | US: ℞-only | 1.00 | infobox |
| Amitriptyline | License data | US DailyMed: Amitriptyline | 1.00 | infobox |
| Amitriptyline | MedlinePlus | a682388 | 1.00 | infobox |
| Amitriptyline | Melting point | 197.5 °C (387.5 °F) | 1.00 | infobox |
| Amitriptyline | Metabolism | Liver (CYP2D6, CYP2C19, CYP3A4) | 1.00 | infobox |
| Amitriptyline | Metabolites | nortriptyline, (E)-10-hydroxynortriptyline | 1.00 | infobox |
| Amitriptyline | Molar mass | 277.411 g·mol−1 | 1.00 | infobox |
| Amitriptyline | Pregnancy category | AU: C | 1.00 | infobox |
| Amitriptyline | Pronunciation | /ˌæmɪˈtrɪptɪliːn/ | 1.00 | infobox |
The concept neighborhoods around Amitriptyline bring nearby vocabulary together. In this analysis, examples include Patients, May and Nortriptyline. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Amitriptyline, one of the stronger structural bridges in this analysis connects Amitriptyline with Medical uses. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Amitriptyline to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Amitriptyline · EN edition · Analysis: TopicsToTalkAbout