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Clonazepam

Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, agitation associated with psychosis, obsessive–compulsive disorder (OCD), and akathisia, with some evidence supporting use in treatment of bipolar mania. It is a long-acting benzodiazepine.

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3D model (JSmol)
Interactive image
Addiction liability
Moderate
AHFS/Drugs.com
Monograph
ATC code
N03AE01 (WHO)
Bioavailability
90%
CAS Number
1622-61-3 Y

Topics to explore

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Overview

Medical uses

Contraindications

Adverse effects

Interactions

Pregnancy

Pharmacology

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Clonazepam

Nodes163
Edges162
Triples209
Avg. degree1.99
Density0.01227
Components1

How this topic connects Entity context

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Clonazepam

Top relations

related to Brand names · 61
Clonazepam → Antelepsin, Argentina, Australia, Austria, Bangladesh, Belgium, Brazil, Canada, China, Clonex, Clonoten, Clonotril, Clotrin, Colombia, Costa Rica, Croatia, Czech Republic, Denmark, Emcloz, Estonia
related to Tolerance and withdrawal · 12
Clonazepam → Chronic, Due, GABA-positive, High, In, Increasing, Like, Many, One-third, The, Tolerance, Withdrawal
related to Pregnancy · 10
Clonazepam → Caution, If, In, IQ, Neonatal, Possible, The, There, This, Withdrawal
Legal status · 9
Clonazepam → AU: S4 (Prescription only), BR: Class B1 (Psychoactive drugs), CA: Schedule IV, DE: Prescription only (Anlage III for higher doses), In general: ℞ (Prescription only), NZ: Class C5, UK: Class C, UN: Psychotropic Schedule IV, US: Schedule IV
related to Less common · 9
Clonazepam → After, Benzodiazepines, ConfusionIrritability, Hallucinations, REM, Short-term, Some, This, While
related to Other · 7
Clonazepam → Benzodiazepines, HyperekplexiaMany, In, It, Studies, The, TRPM8
related to Pharmacokinetics · 7
Clonazepam → CYP3A4, Erythromycin, In, It, P450, Peak, Plasma
related to Muscle disorders · 6
Clonazepam → ALS, Bruxism, It, REM, Restless, The
related to Withdrawal-related · 6
Clonazepam → AnxietyIrritabilityInsomniaTremorsHeadachesStomach, Benzodiazepines, CNS, Many, Physiological, Use
related to Interactions · 4
Clonazepam → Azole, Combined, In, Phenytoin

Important terminology Word statistics

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Important terminology

benzodiazepines may use effects withdrawal tolerance drug benzodiazepine used also levels anticonvulsant pregnancy dependence long-term anxiety gaba seizures doses depression

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Clonazepam3D model (JSmol)Interactive image1.00infobox
ClonazepamAddiction liabilityModerate1.00infobox
ClonazepamAHFS/Drugs.comMonograph1.00infobox
ClonazepamATC codeN03AE01 (WHO)1.00infobox
ClonazepamBioavailability90%1.00infobox
ClonazepamCAS Number1622-61-3 Y1.00infobox
ClonazepamChEBICHEBI:3756 Y1.00infobox
ClonazepamChEMBLChEMBL452 Y1.00infobox
ClonazepamChemSpider2700 Y1.00infobox
ClonazepamCompTox Dashboard (EPA)DTXSID10228451.00infobox
ClonazepamDependence liabilityPhysical: Very high Psychological: Moderate1.00infobox
ClonazepamDrug classBenzodiazepine1.00infobox
ClonazepamDrugBankDB01068 Y1.00infobox
ClonazepamDuration of action8–12 hours1.00infobox
ClonazepamECHA InfoCard100.015.0881.00infobox
ClonazepamElimination half-life19–60 hours1.00infobox
ClonazepamExcretionKidney1.00infobox
ClonazepamFormulaC15H10ClN3O31.00infobox
ClonazepamIUPHAR/BPS69631.00infobox
ClonazepamKEGGD00280 Y1.00infobox
ClonazepamLegal statusAU: S4 (Prescription only)1.00infobox
ClonazepamLegal statusBR: Class B1 (Psychoactive drugs)1.00infobox
ClonazepamLegal statusCA: Schedule IV1.00infobox
ClonazepamLegal statusDE: Prescription only (Anlage III for higher doses)1.00infobox
ClonazepamLegal statusNZ: Class C51.00infobox
ClonazepamLegal statusUK: Class C1.00infobox
ClonazepamLegal statusUS: Schedule IV1.00infobox
ClonazepamLegal statusUN: Psychotropic Schedule IV1.00infobox
ClonazepamLegal statusIn general: ℞ (Prescription only)1.00infobox
ClonazepamLicense dataUS DailyMed: Clonazepam1.00infobox

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