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Phenacetin: History, Culture & Applications

Phenacetin (/fɪˈnæsɪtɪn/ ⓘ; acetophenetidin, N-(4-ethoxyphenyl)acetamide) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887. It was withdrawn from medicinal use as dangerous from the 1970s (e.g., withdrawn in Canada in 1973, and by the U.S. Food and Drug Administration in 1983).

Language: English [EN]
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Phenacetin topic overview

The analysis highlights History, Culture and Applications as prominent areas in the source structure around Phenacetin.

Related topics
52
Source areas
7
Connected nodes
59
Extracted relationships
88
Concept neighborhoods
20
Bridge connections
59

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Safety · 17 topics
Uses · 12 topics
History · 7 topics
Known mechanism of action · 5 topics
Preparation · 5 topics
In popular culture · 3 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
N02BE03 (WHO)
CAS Number
62-44-2 Y
ChEBI
CHEBI:8050 Y
ChEMBL
ChEMBL16073 Y
ChemSpider
4590 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Known mechanism of action

Preparation

Uses

Safety

In popular culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Phenacetin connects Entity context

The extracted context around Phenacetin shows recurring relationship patterns in the source. For example, Phenacetin → Although, Bayer, Britain, During, Elberfeld, German, Germany, It, Jocelyn Field Thorpe, Joseph, Martha Annie Whiteley, Mering's, Prior, World War One Another extracted example is Phenacetin → An, As, Australia, Coricidin, Drug Administration, Food, In, India, It, November, Paracetamol, Roche's Saridon, United States, Vincent's APC. Use these groups to spot repeated connection types before inspecting the individual relationships.

Phenacetin

Top relations

related to history · 14
Phenacetin → Although, Bayer, Britain, During, Elberfeld, German, Germany, It, Jocelyn Field Thorpe, Joseph, Martha Annie Whiteley, Mering's, Prior, World War One
related to Medical · 14
Phenacetin → An, As, Australia, Coricidin, Drug Administration, Food, In, India, It, November, Paracetamol, Roche's Saridon, United States, Vincent's APC
related to Safety · 11
Phenacetin → Acute, Cancer, Chronic, IARC, IgM, In, International Agency, It, Research, The, This
related to In popular culture · 10
Phenacetin → APCs, Art, Care, Duty, In, Justice, Motorcycle Maintenance, This, Yorkshire Television, Zen
related to Known mechanism of action · 7
Phenacetin → Canada, In, It, Phenacetin's, This, United States, Usually
related to External links · 5
Phenacetin → Archived, Carcinogen, MSDS, NIHIARC, Wayback Machine
related to Other · 5
Phenacetin → Canada, Due, It, There, UK
related to Preparation · 4
Phenacetin → Harmon Northrop Morse, Morse's, The, Williamson
3D model (JSmol) · 1
Phenacetin → Interactive image
ATC code · 1
Phenacetin → N02BE03 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

drug used paracetamol analgesic one due also renal use canada properties synthesis containing 1983 carcinogenic known n- 4-ethoxyphenyl acetamide first

Phenacetin relationships Subject–Predicate–Object triples

TTTA extracted 88 structured relationships around Phenacetin. Examples in this analysis include Phenacetin → 3D model (JSmol) → Interactive image and Phenacetin → ATC code → N02BE03 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Phenacetin3D model (JSmol)Interactive image1.00infobox
PhenacetinATC codeN02BE03 (WHO)1.00infobox
PhenacetinCAS Number62-44-2 Y1.00infobox
PhenacetinChEBICHEBI:8050 Y1.00infobox
PhenacetinChEMBLChEMBL16073 Y1.00infobox
PhenacetinChemSpider4590 Y1.00infobox
PhenacetinCompTox Dashboard (EPA)DTXSID10211161.00infobox
PhenacetinDensity1.24 g/cm31.00infobox
PhenacetinDrugBankDB03783 Y1.00infobox
PhenacetinECHA InfoCard100.000.4851.00infobox
PhenacetinFormulaC10H13NO21.00infobox
PhenacetinIUPHAR/BPS74021.00infobox
PhenacetinKEGGD00569 Y1.00infobox
PhenacetinMelting point134 to 137.5 °C (273.2 to 279.5 °F)1.00infobox
PhenacetinMolar mass179.219 g·mol−11.00infobox
PhenacetinPubChem CID47541.00infobox
PhenacetinSolubility in water0.766 g/L (25 °C (77 °F))1.00infobox
PhenacetinUNIIER0CTH01H91.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Phenacetin bring nearby vocabulary together. In this analysis, examples include Used, Due and Containing. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Phenacetin
    • Used
    • Due
    • Containing
    • Renal
    • Analgesic
    • Case
    • Chronic
    • Reformulated
    • Research
    • Properties
    • One
    • Paracetamol
  • phenacetin
    • Used
    • Due
    • Containing
    • Renal
    • Analgesic
    • Case
    • Chronic
    • Reformulated
    • Research
    • Properties
    • One
    • Paracetamol
  • compound analgesic
    • Phenacetin's
    • Effects
    • Known
    • Paracetamol
    • Used
    • Antipyretic
    • Ether
    • N-
    • Phenacetin
    • Popular
    • Safety
    • Widely
  • analgesic nephropathy
    • Phenacetin's
    • Effects
    • Known
    • Paracetamol
    • Used
    • Antipyretic
    • Ether
    • N-
    • Phenacetin
    • Popular
    • Safety
    • Widely
  • u.s. food and drug administration
    • Food
    • Administration
    • Drug
    • Carcinogenic
    • Containing
    • Properties
    • Due
    • Hemolysis
    • N-
    • Widely
    • Market
    • May
  • food and drug administration
    • Food
    • Administration
    • Drug
    • Carcinogenic
    • Containing
    • Properties
    • Due
    • Hemolysis
    • N-
    • Widely
    • Market
    • May
  • known mechanism of action
    • First
    • Also
    • N-
    • Popular
    • Safety
    • Analgesic
    • One
    • Known
    • Market
    • Chronic
    • Properties
    • Use
  • chronic pain
    • Use
    • Known
    • Market
    • May
    • Reformulated
    • Containing
    • Renal
    • Due
    • Phenacetin

Connections between topic areas Semantic bridges

For Phenacetin, one of the stronger structural bridges in this analysis connects Phenacetin with Safety. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Phenacetin — Safety · splits 42 ⟂ 18
Phenacetin — Uses · splits 47 ⟂ 13
Phenacetin — History · splits 52 ⟂ 8
Phenacetin — Known mechanism of action · splits 54 ⟂ 6
Phenacetin — Preparation · splits 54 ⟂ 6
Phenacetin — Overview · splits 56 ⟂ 4
Phenacetin — In popular culture · splits 56 ⟂ 4

Map overview Semantic statistics

Phenacetin

Nodes60
Edges59
Triples88
Avg. degree1.97
Density0.033333
Components1

Source & methodology

TTTA analyzes the structure around Phenacetin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Phenacetin · EN edition · Analysis: TopicsToTalkAbout

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