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Citalopram: History, Community, Culture & Applications

Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social anxiety disorder. The antidepressant effects may take one to four weeks to occur. It is typically taken orally…

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Citalopram topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Citalopram.

Related topics
117
Source areas
10
Connected nodes
127
Extracted relationships
255
Concept neighborhoods
38
Bridge connections
127

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 36 topics
Overview · 19 topics
Medical uses · 17 topics
Interactions · 16 topics
Stereochemistry · 11 topics
Pharmacology · 7 topics
Metabolism · 4 topics
Society and culture · 4 topics
History · 2 topics
Administration · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N06AB04 (WHO)
Bioavailability
80% peak at 4 hours
CAS Number
59729-33-8 Y
ChEBI
CHEBI:3723 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Administration

Adverse effects

Interactions

Pharmacology

Stereochemistry

Metabolism

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Citalopram connects Entity context

The extracted context around Citalopram shows recurring relationship patterns in the source. For example, Citalopram → Actavis, Akarin, Argentina, Australia, Belgium, Bolivia, Brazil, Canada, Celapram, Celexa, Celica, Chile, Ciazil, Cilate, Cilift, Cinapen, Cipram, Cipramil, Cipraned, Ciprapine Another extracted example is Citalopram → However, HTP, It, MAOIs, MDMA, P450, Serotonin, SERT, SRA, SRAs, SSRI, SSRIs, St John's, This, Tryptophan, When, With St John's. Use these groups to spot repeated connection types before inspecting the individual relationships.

Citalopram

Top relations

related to Brand names · 99
Citalopram → Actavis, Akarin, Argentina, Australia, Belgium, Bolivia, Brazil, Canada, Celapram, Celexa, Celica, Chile, Ciazil, Cilate, Cilift, Cinapen, Cipram, Cipramil, Cipraned, Ciprapine
related to Serotonin syndrome · 17
Citalopram → However, HTP, It, MAOIs, MDMA, P450, Serotonin, SERT, SRA, SRAs, SSRI, SSRIs, St John's, This, Tryptophan, When, With St John's
related to Metabolism · 10
Citalopram → After, Approximately, CYP2C19, CYP2D6, CYP3A4, Metabolites, Potent, The, Tobacco, With
related to European Commission fine · 8
Citalopram → Danish, European, European Commission, June, Lundbeck, Lundbeck's, On, This
related to Post-SSRI sexual dysfunction · 8
Citalopram → Characteristic, In, PSSD, Sexual, SSRI, SSRIs, The, The DSM-5
has effect · 7
Citalopram → As, If, Less, Other, Rare, Some, SSRIs
related to Stereochemistry · 7
Citalopram → As, In, Lundbeck, N-dimethyl-3-aminopropyl, Only, They, Whereas
related to Depression · 6
Citalopram → Clinical Excellence, Evidence, Health, In, National Institute, United States
related to history · 6
Citalopram → Denmark, It, Klaus Bøgesø, Lundbeck, The, US
related to Overdose · 6
Citalopram → Blood, It, N-desmethylcitalopram, Overdosage, Overdose, SSRIs

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

serotonin may effects ssris side risk sexual european taken disorder also dysfunction ssri escitalopram patients including nausea syndrome antidepressant -citalopram

Citalopram relationships Subject–Predicate–Object triples

TTTA extracted 255 structured relationships around Citalopram. Examples in this analysis include Citalopram → 3D model (JSmol) → Interactive image and Citalopram → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Citalopram3D model (JSmol)Interactive image1.00infobox
CitalopramAHFS/Drugs.comMonograph1.00infobox
CitalopramATC codeN06AB04 (WHO)1.00infobox
CitalopramBioavailability80% peak at 4 hours1.00infobox
CitalopramCAS Number59729-33-8 Y1.00infobox
CitalopramChEBICHEBI:3723 Y1.00infobox
CitalopramChEMBLChEMBL549 Y1.00infobox
CitalopramChemSpider2669 Y1.00infobox
CitalopramChiralityRacemic mixture1.00infobox
CitalopramCompTox Dashboard (EPA)DTXSID80228261.00infobox
CitalopramDependence liabilityLow/none1.00infobox
CitalopramDrug classSelective serotonin reuptake inhibitor (SSRI)1.00infobox
CitalopramDrugBankDB00215 Y1.00infobox
CitalopramECHA InfoCard100.056.2471.00infobox
CitalopramElimination half-life35 hours1.00infobox
CitalopramExcretionMostly as unmetabolized citalopram, partly DCT, and traces of DDCT in urine1.00infobox
CitalopramFormulaC20H21FN2O1.00infobox
CitalopramIUPHAR/BPS75471.00infobox
CitalopramKEGGD07704 Y1.00infobox
CitalopramKEGGas salt: D00822 Y1.00infobox
CitalopramLegal statusAU: S4 (Prescription only)1.00infobox
CitalopramLegal statusBR: Class C1 (Other controlled substances)1.00infobox
CitalopramLegal statusCA: ℞-only1.00infobox
CitalopramLegal statusUK: POM (Prescription only)1.00infobox
CitalopramLegal statusUS: ℞-only1.00infobox
CitalopramLicense dataUS DailyMed: Citalopram1.00infobox
CitalopramMedlinePlusa6990011.00infobox
CitalopramMetabolismLiver (CYP3A4 and CYP2C19)1.00infobox
CitalopramMetabolitesDesmethylcitalopram (DCT) and didesmethylcitalopram (DDCT)1.00infobox
CitalopramMolar mass324.399 g·mol−11.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Citalopram bring nearby vocabulary together. In this analysis, examples include Ssris, May and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Citalopram
    • Ssris
    • May
    • Effects
    • Serotonin
    • Escitalopram
    • Increase
    • Disorder
    • European
    • Syndrome
    • Including
    • Ssri
    • Risk
  • citalopram
    • Ssris
    • May
    • Effects
    • Serotonin
    • Escitalopram
    • Increase
    • Disorder
    • European
    • Syndrome
    • Including
    • Ssri
    • Risk
  • selective serotonin reuptake inhibitor
    • Inhibitor
    • Reuptake
    • Serotonin
    • Effects
    • Exposure
    • -citalopram
    • Syndrome
    • Ssri
    • Dysfunction
    • Sexual
    • Side
    • Taken
  • social anxiety disorder
    • Anxiety
    • Disorder
    • Used
    • European
    • Administration
    • Include
    • States
    • Discontinuation
    • Exposure
    • Inhibitor
    • United
    • -citalopram
  • european
    • Drug
    • Dysfunction
    • Including
    • Sexual
    • Administration
    • Lundbeck
    • Generic
    • Treatment
    • United
    • Risk
    • Health
    • States
  • post-ssri sexual dysfunction
    • Dysfunction
    • Sexual
    • Drug
    • European
    • Including
    • Patients
    • Risk
    • Discontinuation
    • May
    • Reuptake
    • Ssris
    • Side
  • european medicines agency
    • Drug
    • Dysfunction
    • Including
    • Sexual
    • Administration
    • Lundbeck
    • Generic
    • Treatment
    • United
    • Risk
    • Health
    • States
  • serotonin syndrome
    • Effects
    • Syndrome
    • Ssri
    • Taken
    • Side
    • May
    • Exposure
    • -citalopram
    • Associated
    • Drug
    • Increased
    • Also

Connections between topic areas Semantic bridges

For Citalopram, one of the stronger structural bridges in this analysis connects Citalopram with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Citalopram — Adverse effects · splits 91 ⟂ 37
Citalopram — Overview · splits 108 ⟂ 20
Citalopram — Medical uses · splits 110 ⟂ 18
Citalopram — Interactions · splits 111 ⟂ 17
Citalopram — Stereochemistry · splits 116 ⟂ 12
Citalopram — Pharmacology · splits 120 ⟂ 8
Citalopram — Metabolism · splits 123 ⟂ 5
Citalopram — Society and culture · splits 123 ⟂ 5
Citalopram — History · splits 125 ⟂ 3

Map overview Semantic statistics

Citalopram

Nodes128
Edges127
Triples255
Avg. degree1.98
Density0.015625
Components1

Source & methodology

TTTA analyzes the structure around Citalopram to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Citalopram · EN edition · Analysis: TopicsToTalkAbout

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