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Myocyte-specific enhancer factor 2A: Art, Interactions & Overview

Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. MEF2A is a transcription factor in the Mef2 family. In humans it is located on chromosome 15q26. Certain mutations in MEF2A cause an autosomal dominant form of coronary artery disease and myocardial infarction.

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Myocyte-specific enhancer factor 2A topic overview

The analysis highlights Art, Interactions and Overview as prominent areas in the source structure around Myocyte-specific enhancer factor 2A.

Related topics
19
Source areas
2
Connected nodes
21
Extracted relationships
115
Related term clusters
7
Bridge connections
21

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 10 topics
Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57
Band
15q26.3 · 7 C|7 36.72 cM
Bgee
Achilles tendon · myocardium · cardiac muscle tissue of right atrium · right ventricle · myocardium of left ventricle
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

For the semantics nerds

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Advanced semantic analysis

How Myocyte-specific enhancer factor 2A connects Entity context

The extracted context around Myocyte-specific enhancer factor 2A shows recurring relationship patterns in the source. For example, Myocyte-specific enhancer factor 2A → apoptotic process, cardiac conduction, cell differentiation, cellular response to calcium ion, chromatin binding, cytosol, dendrite morphogenesis, development of the heart, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, ERK5 cascade, histone acetyltransferase binding, histone deacetylase binding, MAPK cascade, mitochondrial genome maintenance, mitochondrion distribution, multicellular organism development, muscle organ development Another extracted example is Myocyte-specific enhancer factor 2A → Achilles tendon, ankle, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, myocardium, myocardium of left ventricle, right ventricle, Skeletal muscle tissue of biceps brachii, skin of thigh, stroma of bone marrow, tibia. Use these groups to spot repeated connection types before inspecting the individual relationships.

Myocyte-specific enhancer factor 2A

Top relations

Gene ontology · 44
Myocyte-specific enhancer factor 2A → apoptotic process, cardiac conduction, cell differentiation, cellular response to calcium ion, chromatin binding, cytosol, dendrite morphogenesis, development of the heart, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, ERK5 cascade, histone acetyltransferase binding, histone deacetylase binding, MAPK cascade, mitochondrial genome maintenance, mitochondrion distribution, multicellular organism development, muscle organ development
Bgee · 19
Myocyte-specific enhancer factor 2A → Achilles tendon, ankle, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, myocardium, myocardium of left ventricle, right ventricle, Skeletal muscle tissue of biceps brachii, skin of thigh, stroma of bone marrow, tibia
RNA expression pattern · 19
Myocyte-specific enhancer factor 2A → Achilles tendon, ankle, atrioventricular valve, atrium, biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, myocardium, myocardium of left ventricle, right ventricle, Skeletal muscle tissue of biceps brachii, skin of thigh, stroma of bone marrow, tibia
related to Interactions · 9
Myocyte-specific enhancer factor 2A → ASCL1, EP300, HDAC4, HDAC9, Histone, MAPK14, MEF2D, Mothers, Myocyte-specific
Band · 2
Myocyte-specific enhancer factor 2A → 15q26.3, 7 C|7 36.72 cM
Chr. · 2
Myocyte-specific enhancer factor 2A → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
Myocyte-specific enhancer factor 2A → 67,372,858 bp, 99,716,488 bp
Aliases · 1
Myocyte-specific enhancer factor 2A → MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A
Available structures · 1
Myocyte-specific enhancer factor 2A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57
BioGPS · 1
Myocyte-specific enhancer factor 2A → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mef2a bp gene human factor chromosome chr band enhancer mef2 15 2a transcription location myocyte-specific family humans protein mouse dna

Myocyte-specific enhancer factor 2A relationships Subject–Predicate–Object triples

TTTA extracted 115 structured relationships around Myocyte-specific enhancer factor 2A. Examples in this analysis include Myocyte-specific enhancer factor 2A → Aliases → MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A and Myocyte-specific enhancer factor 2A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P57. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Myocyte-specific enhancer factor 2AAliasesMEF2A, ADCAD1, RSRFC4, RSRFC9, mef2, myocyte enhancer factor 2A1.00infobox
Myocyte-specific enhancer factor 2AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C7U, 1EGW, 1LEW, 3KOV, 3MU6, 3P571.00infobox
Myocyte-specific enhancer factor 2ABand15q26.31.00infobox
Myocyte-specific enhancer factor 2ABand7 C|7 36.72 cM1.00infobox
Myocyte-specific enhancer factor 2ABgeeAchilles tendon1.00infobox
Myocyte-specific enhancer factor 2ABgeemyocardium1.00infobox
Myocyte-specific enhancer factor 2ABgeecardiac muscle tissue of right atrium1.00infobox
Myocyte-specific enhancer factor 2ABgeeright ventricle1.00infobox
Myocyte-specific enhancer factor 2ABgeemyocardium of left ventricle1.00infobox
Myocyte-specific enhancer factor 2ABgeebiceps brachii1.00infobox
Myocyte-specific enhancer factor 2ABgeeSkeletal muscle tissue of biceps brachii1.00infobox
Myocyte-specific enhancer factor 2ABgeeskin of thigh1.00infobox
Myocyte-specific enhancer factor 2ABgeemiddle temporal gyrus1.00infobox
Myocyte-specific enhancer factor 2ABgeetibia1.00infobox
Myocyte-specific enhancer factor 2ABgeemedial dorsal nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeelateral geniculate nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeelateral septal nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeemedial geniculate nucleus1.00infobox
Myocyte-specific enhancer factor 2ABgeeatrioventricular valve1.00infobox
Myocyte-specific enhancer factor 2ABgeestroma of bone marrow1.00infobox
Myocyte-specific enhancer factor 2ABgeeatrium1.00infobox
Myocyte-specific enhancer factor 2ABgeecerebellar vermis1.00infobox
Myocyte-specific enhancer factor 2ABgeeankle1.00infobox
Myocyte-specific enhancer factor 2ABioGPSMore reference expression data1.00infobox
Myocyte-specific enhancer factor 2AChr.Chromosome 15 (human)1.00infobox
Myocyte-specific enhancer factor 2AChr.Chromosome 7 (mouse)1.00infobox
Myocyte-specific enhancer factor 2ADatabasesNCBI: entry; OMA: entry1.00infobox
Myocyte-specific enhancer factor 2AEnd99,716,488 bp1.00infobox
Myocyte-specific enhancer factor 2AEnd67,372,858 bp1.00infobox
Myocyte-specific enhancer factor 2AEnsemblENSG000000683051.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Myocyte-specific enhancer factor 2A bring nearby vocabulary together. In this analysis, examples include Factor, 2a and Enhancer. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Myocyte-specific enhancer factor 2A
    • Factor
    • 2a
    • Enhancer
    • Myocyte-specific
    • Family
    • Function
    • Search
    • Gene
    • Location
    • Mef2
    • Binding
    • Bp
  • myocyte-specific enhancer factor 2a
    • Factor
    • Gene
    • Mef2a
    • Omim
    • 2a
    • Enhancer
    • Myocyte-specific
    • Transcription
    • Family
    • Human
    • Mef2
    • Binding
  • gene
    • Human
    • Location
    • Bp
    • Chr
    • Chromosome
    • Mef2a
    • Dna-binding
    • End
    • Function
    • Mouse
    • Omim
    • Protein
  • transcription factor
    • Dna-binding
    • Gene
    • Mef2a
    • 2a
    • Factor
    • Transcription
    • Factors
    • Family
    • Human
    • Mef2
    • Function
    • Omim
  • chromosome 15q26
    • Bp
    • Chr
    • Human
    • Location
    • Band
    • Gene
    • 15q26
    • Chromosome
    • End
    • Function
    • Mouse
    • Search
  • mef2
    • Family
    • Omim
    • Dna
    • Myocyte-specific
    • Proteins
    • Regulatory
    • Transcription
    • Human
    • Mef2a
    • External
    • Binding
    • Dna-binding
  • protein
    • Search
    • Regulatory
    • Transcription

Connections between topic areas Semantic bridges

For Myocyte-specific enhancer factor 2A, one of the stronger structural bridges in this analysis connects Myocyte-specific enhancer factor 2A with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Myocyte-specific enhancer factor 2A — Interactions · splits 11 ⟂ 11
Myocyte-specific enhancer factor 2A — Overview · splits 12 ⟂ 10

Map overview Semantic statistics

Myocyte-specific enhancer factor 2A

Nodes22
Edges21
Triples115
Avg. degree1.91
Density0.090909
Components1

Source & methodology

TTTA analyzes the structure around Myocyte-specific enhancer factor 2A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Myocyte-specific enhancer factor 2A · EN edition · Analysis: TopicsToTalkAbout

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