Homeobox protein CDX-2

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Explore the main themes, entities and connections around Homeobox protein CDX-2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Gastrointestinal tract Embryonic development Endodermal cells Epithelium Placenta

7 related topics

Possible use in stem cell research

President's Council on Bioethics Stem cell Hnf4 Gastrulation

4 related topics

Pathology

Acute myeloid leukemia Barrett's esophagus Bile acids

3 related topics

Interactions

Interact EP300 PAX6

3 related topics

Key facts & relationships

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Aliases: CDX2, CDX-3, CDX2/AS, CDX3, caudal type homeobox 2, Cdx2
Band: 13q12.2 · 5 G3|5 86.86 cM
Bgee: mucosa of transverse colon · rectum · duodenum · epithelium of colon · mucosa of ileum
BioGPS: More reference expression data
Chr.: Chromosome 13 (human) · Chromosome 5 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Function

Pathology

Possible use in stem cell research

Interactions

Interact Protein-protein interaction
EP300
PAX6

Advanced semantic analysis

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Map overview Semantic statistics

Nodes34

Edges33

Triples100

Avg. degree1.94

Density0.058824

Components1

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Homeobox protein CDX-2

Top relations

Gene ontology · 39

Homeobox protein CDX-2 → animal organ morphogenesis, anterior/posterior axis specification, anterior/posterior pattern specification, blastocyst development, blood vessel development, cell differentiation, condensed nuclear chromosome, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, double-stranded DNA binding, endosome to lysosome transport, establishment or maintenance of epithelial cell apical/basal polarity, intestinal epithelial cell differentiation, labyrinthine layer development, methyl-CpG binding, multicellular organism development, negative regulation of transcription by RNA polymerase II, nucleoplasm

Bgee · 19

Homeobox protein CDX-2 → appendix, body of pancreas, crypt of lieberkuhn of small intestine, duodenum, epithelium of colon, Epithelium of large intestine, ileum, islet of Langerhans, jejunal mucosa, jejunum, left colon, migratory enteric neural crest cell, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, Paneth cell, primitive streak, rectum, tail of embryo

RNA expression pattern · 19

Band · 2

Homeobox protein CDX-2 → 13q12.2, 5 G3|5 86.86 cM

Chr. · 2

Homeobox protein CDX-2 → Chromosome 13 (human), Chromosome 5 (mouse)

End · 2

Homeobox protein CDX-2 → 147,244,080 bp, 27,969,315 bp

Aliases · 1

Homeobox protein CDX-2 → CDX2, CDX-3, CDX2/AS, CDX3, caudal type homeobox 2, Cdx2

BioGPS · 1

Homeobox protein CDX-2 → More reference expression data

Databases · 1

Homeobox protein CDX-2 → NCBI: entry; OMA: entry

Ensembl · 1

Homeobox protein CDX-2 → ENSG00000165556

Important terminology Word statistics

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Important terminology

cdx2 human gene intestinal cells bp development chr band protein genes stem function homeobox chromosome 13 expression differentiation expressed location

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Homeobox protein CDX-2	Aliases	CDX2, CDX-3, CDX2/AS, CDX3, caudal type homeobox 2, Cdx2	1.00	infobox
Homeobox protein CDX-2	Band	13q12.2	1.00	infobox
Homeobox protein CDX-2	Band	5 G3\|5 86.86 cM	1.00	infobox
Homeobox protein CDX-2	Bgee	mucosa of transverse colon	1.00	infobox
Homeobox protein CDX-2	Bgee	rectum	1.00	infobox
Homeobox protein CDX-2	Bgee	duodenum	1.00	infobox
Homeobox protein CDX-2	Bgee	epithelium of colon	1.00	infobox
Homeobox protein CDX-2	Bgee	mucosa of ileum	1.00	infobox
Homeobox protein CDX-2	Bgee	mucosa of sigmoid colon	1.00	infobox
Homeobox protein CDX-2	Bgee	appendix	1.00	infobox
Homeobox protein CDX-2	Bgee	jejunal mucosa	1.00	infobox
Homeobox protein CDX-2	Bgee	body of pancreas	1.00	infobox
Homeobox protein CDX-2	Bgee	islet of Langerhans	1.00	infobox
Homeobox protein CDX-2	Bgee	Paneth cell	1.00	infobox
Homeobox protein CDX-2	Bgee	tail of embryo	1.00	infobox
Homeobox protein CDX-2	Bgee	crypt of lieberkuhn of small intestine	1.00	infobox
Homeobox protein CDX-2	Bgee	primitive streak	1.00	infobox
Homeobox protein CDX-2	Bgee	migratory enteric neural crest cell	1.00	infobox
Homeobox protein CDX-2	Bgee	ileum	1.00	infobox
Homeobox protein CDX-2	Bgee	jejunum	1.00	infobox
Homeobox protein CDX-2	Bgee	Epithelium of large intestine	1.00	infobox
Homeobox protein CDX-2	Bgee	left colon	1.00	infobox
Homeobox protein CDX-2	BioGPS	More reference expression data	1.00	infobox
Homeobox protein CDX-2	Chr.	Chromosome 13 (human)	1.00	infobox
Homeobox protein CDX-2	Chr.	Chromosome 5 (mouse)	1.00	infobox
Homeobox protein CDX-2	Databases	NCBI: entry; OMA: entry	1.00	infobox
Homeobox protein CDX-2	End	27,969,315 bp	1.00	infobox
Homeobox protein CDX-2	End	147,244,080 bp	1.00	infobox
Homeobox protein CDX-2	Ensembl	ENSG00000165556	1.00	infobox
Homeobox protein CDX-2	Entrez	1045	1.00	infobox

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