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Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around IRF2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around IRF2 shows recurring relationship patterns in the source. For example, IRF2 → blood coagulation, cell population proliferation, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, focal adhesion, immune system process, interferon-gamma-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, protein binding, regulation of transcription, DNA-templated, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription by RNA polymerase II, transcription, DNA-templated, type I interferon signaling pathway Another extracted example is IRF2 → Achilles tendon, appendix, blood, duodenum, granulocyte, left colon, left lobe of liver, lymph node, mesenteric lymph nodes, monocyte, muscle of thigh, olfactory zone of nasal mucosa, rectum, right adrenal cortex, spleen, tail of embryo, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp human interferon regulatory chr band gene factor chromosome protein location mouse transcription function external search 474 558 end 184
TTTA extracted 84 structured relationships around IRF2. Examples in this analysis include IRF2 → Aliases → IRF2, IRF-2, interferon regulatory factor 2 and IRF2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IRF, 1IRG, 2IRF. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IRF2 | Aliases | IRF2, IRF-2, interferon regulatory factor 2 | 1.00 | infobox |
| IRF2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IRF, 1IRG, 2IRF | 1.00 | infobox |
| IRF2 | Band | 4q35.1 | 1.00 | infobox |
| IRF2 | Band | 8|8 B1.1 | 1.00 | infobox |
| IRF2 | Bgee | monocyte | 1.00 | infobox |
| IRF2 | Bgee | blood | 1.00 | infobox |
| IRF2 | Bgee | Achilles tendon | 1.00 | infobox |
| IRF2 | Bgee | granulocyte | 1.00 | infobox |
| IRF2 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| IRF2 | Bgee | appendix | 1.00 | infobox |
| IRF2 | Bgee | spleen | 1.00 | infobox |
| IRF2 | Bgee | lymph node | 1.00 | infobox |
| IRF2 | Bgee | rectum | 1.00 | infobox |
| IRF2 | Bgee | right adrenal cortex | 1.00 | infobox |
| IRF2 | Bgee | left colon | 1.00 | infobox |
| IRF2 | Bgee | left lobe of liver | 1.00 | infobox |
| IRF2 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| IRF2 | Bgee | muscle of thigh | 1.00 | infobox |
| IRF2 | Bgee | thymus | 1.00 | infobox |
| IRF2 | Bgee | duodenum | 1.00 | infobox |
| IRF2 | Bgee | tail of embryo | 1.00 | infobox |
| IRF2 | BioGPS | More reference expression data | 1.00 | infobox |
| IRF2 | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| IRF2 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| IRF2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IRF2 | End | 184,474,558 bp | 1.00 | infobox |
| IRF2 | End | 47,300,493 bp | 1.00 | infobox |
| IRF2 | Ensembl | ENSG00000168310 | 1.00 | infobox |
| IRF2 | Entrez | 3660 | 1.00 | infobox |
| IRF2 | External IDs | OMIM: 147576; MGI: 96591; GeneCards: IRF2 | 1.00 | infobox |
The concept neighborhoods around IRF2 bring nearby vocabulary together. In this analysis, examples include Regulatory, Protein and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For IRF2, one of the stronger structural bridges in this analysis connects IRF2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around IRF2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — IRF2 · EN edition · Analysis: TopicsToTalkAbout
