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TAL1: Interactions & Overview

T-cell acute lymphocytic leukemia protein 1 (i.e. TAL1 but also termed stem cell leukemia/T-cell acute leukemia 1 [i.e. SCL/TAL1]) is a protein that in humans is encoded by the TAL1 gene.

Language: English [EN]
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TAL1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around TAL1.

Related topics
14
Source areas
2
Connected nodes
16
Extracted relationships
131
Concept neighborhoods
8
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 10 topics
Overview · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TAL1, SCL, TCL5, bHLHa17, tal-1, T-cell acute lymphocytic leukemia 1, TAL bHLH transcription factor 1, erythroid differentiation factor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YPA, 2YPB
Band
1p33 · 4 D1|4 52.73 cM
Bgee
trabecular bone · monocyte · bone marrow · right lung · endothelial cell
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TAL1 connects Entity context

The extracted context around TAL1 shows recurring relationship patterns in the source. For example, TAL1 → angiogenesis, astrocyte fate commitment, basophil differentiation, cell differentiation, cell fate commitment, chromatin binding, definitive hemopoiesis, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, embryonic hemopoiesis, enzyme binding, erythrocyte differentiation, erythrocyte maturation, generation of neurons, hemangioblast cell differentiation, hematopoietic stem cell differentiation, hemopoiesis, histone deacetylase binding Another extracted example is TAL1 → blood, bone marrow, bone marrow cell, buccal mucosa cell, embryo, endocardial cushion, endothelial cell, epithelium of colon, fetal liver hematopoietic progenitor cell, genital tubercle, human fetus, monocyte, right lung, spleen, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

TAL1

Top relations

Gene ontology · 59
TAL1 → angiogenesis, astrocyte fate commitment, basophil differentiation, cell differentiation, cell fate commitment, chromatin binding, definitive hemopoiesis, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, embryonic hemopoiesis, enzyme binding, erythrocyte differentiation, erythrocyte maturation, generation of neurons, hemangioblast cell differentiation, hematopoietic stem cell differentiation, hemopoiesis, histone deacetylase binding
Bgee · 18
TAL1 → blood, bone marrow, bone marrow cell, buccal mucosa cell, embryo, endocardial cushion, endothelial cell, epithelium of colon, fetal liver hematopoietic progenitor cell, genital tubercle, human fetus, monocyte, right lung, spleen, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac
RNA expression pattern · 18
TAL1 → blood, bone marrow, bone marrow cell, buccal mucosa cell, embryo, endocardial cushion, endothelial cell, epithelium of colon, fetal liver hematopoietic progenitor cell, genital tubercle, human fetus, monocyte, right lung, spleen, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac
related to Interactions · 8
TAL1 → CBFA2T3, EP300, GATA1, LDB1, LMO1, LMO2, SIN3A, Sp1
related to External links · 4
TAL1 → FactorBookTAL1, Medicine Medical Subject Headings, MeSH, National Library
Band · 2
TAL1 → 1p33, 4 D1|4 52.73 cM
Chr. · 2
TAL1 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
TAL1 → 114,928,952 bp, 47,232,225 bp
Aliases · 1
TAL1 → TAL1, SCL, TCL5, bHLHa17, tal-1, T-cell acute lymphocytic leukemia 1, TAL bHLH transcription factor 1, erythroid differentiation factor
Available structures · 1
TAL1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YPA, 2YPB

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein bp human chr band gene transcription factor chromosome t-cell acute leukemia location encoded mouse lymphocytic stem cell scl external

TAL1 relationships Subject–Predicate–Object triples

TTTA extracted 131 structured relationships around TAL1. Examples in this analysis include TAL1 → Aliases → TAL1, SCL, TCL5, bHLHa17, tal-1, T-cell acute lymphocytic leukemia 1, TAL bHLH transcription factor 1, erythroid differentiation factor and TAL1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YPA, 2YPB. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TAL1AliasesTAL1, SCL, TCL5, bHLHa17, tal-1, T-cell acute lymphocytic leukemia 1, TAL bHLH transcription factor 1, erythroid differentiation factor1.00infobox
TAL1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YPA, 2YPB1.00infobox
TAL1Band1p331.00infobox
TAL1Band4 D1|4 52.73 cM1.00infobox
TAL1Bgeetrabecular bone1.00infobox
TAL1Bgeemonocyte1.00infobox
TAL1Bgeebone marrow1.00infobox
TAL1Bgeeright lung1.00infobox
TAL1Bgeeendothelial cell1.00infobox
TAL1Bgeeblood1.00infobox
TAL1Bgeeupper lobe of left lung1.00infobox
TAL1Bgeebone marrow cell1.00infobox
TAL1Bgeebuccal mucosa cell1.00infobox
TAL1Bgeeepithelium of colon1.00infobox
TAL1Bgeefetal liver hematopoietic progenitor cell1.00infobox
TAL1Bgeetibiofemoral joint1.00infobox
TAL1Bgeehuman fetus1.00infobox
TAL1Bgeeembryo1.00infobox
TAL1Bgeespleen1.00infobox
TAL1Bgeeendocardial cushion1.00infobox
TAL1Bgeeyolk sac1.00infobox
TAL1Bgeegenital tubercle1.00infobox
TAL1BioGPSMore reference expression data1.00infobox
TAL1Chr.Chromosome 1 (human)1.00infobox
TAL1Chr.Chromosome 4 (mouse)1.00infobox
TAL1DatabasesNCBI: entry; OMA: entry1.00infobox
TAL1End47,232,225 bp1.00infobox
TAL1End114,928,952 bp1.00infobox
TAL1EnsemblENSG000001623671.00infobox
TAL1Entrez68861.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TAL1 bring nearby vocabulary together. In this analysis, examples include Factor, Transcription and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • TAL1
    • Factor
    • Transcription
    • Gene
    • Human
    • Cell
    • Differentiation
    • Encoded
    • Scl
    • Search
    • Stem
    • Location
    • T-cell
  • tal1
    • Factor
    • Transcription
    • Gene
    • Human
    • Cell
    • Differentiation
    • Encoded
    • Scl
    • Search
    • Stem
    • Location
    • T-cell
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • D1
    • Differentiation
    • End
    • Human
    • Mouse
    • Scl
    • Search
    • Tal1
  • transcription factor
    • Factor
    • Transcription
    • Differentiation
    • Search
    • Location
    • Tal1
    • Chromosome
    • Gene
    • Basic
    • Bp
    • Chr
    • External
  • sp1 transcription factor
    • Factor
    • Transcription
    • Differentiation
    • Search
    • Location
    • Tal1
    • Chromosome
    • Gene
    • Basic
    • Bp
    • Chr
    • External
  • protein
    • Tal1
    • Encoded
    • Factor
    • Transcription
    • Gene
    • Human
    • Basic
    • Helix-loop-helix
    • Humans
    • Cell
    • D1
    • Differentiation
  • interactions
    • External
    • Reading
    • References
    • Differentiation
    • Lymphocytic
    • Scl
    • Search
    • Leukemia
    • Location
    • T-cell
    • Transcription
    • Chromosome
  • basic helix-loop-helix
    • Helix-loop-helix
    • Encoded
    • Factor
    • Transcription
    • Protein
    • Tal1

Connections between topic areas Semantic bridges

For TAL1, one of the stronger structural bridges in this analysis connects TAL1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TAL1Interactions · splits 6 ⟂ 11
TAL1Overview · splits 12 ⟂ 5

Map overview Semantic statistics

TAL1

Nodes17
Edges16
Triples131
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around TAL1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TAL1 · EN edition · Analysis: TopicsToTalkAbout

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