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Reelin, encoded by the RELN gene, is a large secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates synaptic plasticity by…
The analysis highlights Discovery, Tissue distribution and secretion and Mechanism of action as prominent areas in the source structure around Reelin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Reelin shows recurring relationship patterns in the source. For example, Reelin → associative learning, axon guidance, brain development, cell adhesion, cell migration, cell morphogenesis involved in differentiation, central nervous system development, cerebral cortex development, cerebral cortex tangential migration, cytoplasm, dendrite, dendrite development, extracellular matrix, extracellular region, extracellular space, forebrain development, glial cell differentiation, hippocampus development, hydrolase activity, lateral motor column neuron migration Another extracted example is Reelin → According, AD, All, Alzheimer's, AMPA, ApoE, ApoE4, ApoER2, Apolipoprotein, Aβ-induced, Cajal-Retzius, E2, E3, E4, In, LDL, NMDA, NMDA-receptor, RELN, The. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene expression reln study brain role cells protein schizophrenia one found neurons dab1 also mice apoer2 receptors migration reeler levels
TTTA extracted 351 structured relationships around Reelin. Examples in this analysis include Reelin → Aliases → RELN, LIS2, PRO1598, RL, reelin, ETL7 and Reelin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ddu, 2e26, 2DDU, 2E26, 3A7Q. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Reelin | Aliases | RELN, LIS2, PRO1598, RL, reelin, ETL7 | 1.00 | infobox |
| Reelin | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ddu, 2e26, 2DDU, 2E26, 3A7Q | 1.00 | infobox |
| Reelin | Band | 7q22.1 | 1.00 | infobox |
| Reelin | Band | 5 A3|5 9.98 cM | 1.00 | infobox |
| Reelin | Bgee | olfactory bulb | 1.00 | infobox |
| Reelin | Bgee | cerebellar vermis | 1.00 | infobox |
| Reelin | Bgee | cerebellar hemisphere | 1.00 | infobox |
| Reelin | Bgee | paraflocculus of cerebellum | 1.00 | infobox |
| Reelin | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| Reelin | Bgee | spinal ganglia | 1.00 | infobox |
| Reelin | Bgee | trigeminal ganglion | 1.00 | infobox |
| Reelin | Bgee | endothelial cell | 1.00 | infobox |
| Reelin | Bgee | tibial nerve | 1.00 | infobox |
| Reelin | Bgee | pons | 1.00 | infobox |
| Reelin | Bgee | ciliary body | 1.00 | infobox |
| Reelin | Bgee | lobe of cerebellum | 1.00 | infobox |
| Reelin | Bgee | iris | 1.00 | infobox |
| Reelin | Bgee | sciatic nerve | 1.00 | infobox |
| Reelin | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| Reelin | Bgee | superior colliculus | 1.00 | infobox |
| Reelin | Bgee | paraventricular nucleus of hypothalamus | 1.00 | infobox |
| Reelin | Bgee | piriform cortex | 1.00 | infobox |
| Reelin | BioGPS | More reference expression data | 1.00 | infobox |
| Reelin | Chr. | Chromosome 7 (human) | 1.00 | infobox |
| Reelin | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| Reelin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Reelin | End | 103,989,658 bp | 1.00 | infobox |
| Reelin | End | 22,549,700 bp | 1.00 | infobox |
| Reelin | Ensembl | ENSG00000189056 | 1.00 | infobox |
| Reelin | Entrez | 5649 | 1.00 | infobox |
The concept neighborhoods around Reelin bring nearby vocabulary together. In this analysis, examples include Expression, Cells and Role. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Reelin, one of the stronger structural bridges in this analysis connects Reelin with Possible pathological role. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Reelin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Discovery, Tissue distribution and secretion & Mechanism of action, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Reelin · EN edition · Analysis: TopicsToTalkAbout