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VLDL receptor: Art, Tissue distribution and expression & Associated disorders

The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by Tokuo Yamamoto and Sadao Takahashi, VLDLR is widely distributed throughout the tissues of the body, including the heart…

Language: English [EN]
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VLDL receptor topic overview

The analysis highlights Art, Tissue distribution and expression and Associated disorders as prominent areas in the source structure around VLDL receptor.

Related topics
107
Source areas
6
Connected nodes
113
Extracted relationships
105
Concept neighborhoods
33
Bridge connections
113

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 33 topics
Tissue distribution and expression · 27 topics
Associated disorders · 23 topics
Protein structure · 12 topics
Ligand binding · 8 topics
Function · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
VLDLR, CAMRQ1, CARMQ1, CHRMQ1, VLDLRCH, VLDL-R, very low density lipoprotein receptor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V9U, 3DPR
Band
9p24.2 · 19 C1|19 21.77 cM
Bgee
right ventricle · left ovary · right ovary · myocardium of left ventricle · islet of Langerhans
BioGPS
n/a
Chr.
Chromosome 9 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein structure

Ligand binding

Tissue distribution and expression

Function

Associated disorders

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How VLDL receptor connects Entity context

The extracted context around VLDL receptor shows recurring relationship patterns in the source. For example, VLDL receptor → apolipoprotein binding, axon guidance, calcium ion binding, calcium-dependent protein binding, cargo receptor activity, cholesterol metabolic process, clathrin-coated pit, dendrite morphogenesis, endocytosis, extracellular space, glycoprotein transport, integral component of membrane, lipid metabolism, lipid transport, low-density lipoprotein particle receptor activity, low-density lipoprotein particle receptor catabolic process, lysosomal membrane, membrane, memory, negative regulation of transcription by RNA polymerase II Another extracted example is VLDL receptor → ankle, biceps brachii, body of femur, body of pancreas, cardiac muscle tissue of right atrium, decidua, digastric muscle, gingival epithelium, islet of Langerhans, left ovary, molar, myocardium of left ventricle, retinal pigment epithelium, right auricle of heart, right ovary, right ventricle, sternocleidomastoid muscle, temporal muscle, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

VLDL receptor

Top relations

Gene ontology · 37
VLDL receptor → apolipoprotein binding, axon guidance, calcium ion binding, calcium-dependent protein binding, cargo receptor activity, cholesterol metabolic process, clathrin-coated pit, dendrite morphogenesis, endocytosis, extracellular space, glycoprotein transport, integral component of membrane, lipid metabolism, lipid transport, low-density lipoprotein particle receptor activity, low-density lipoprotein particle receptor catabolic process, lysosomal membrane, membrane, memory, negative regulation of transcription by RNA polymerase II
Bgee · 19
VLDL receptor → ankle, biceps brachii, body of femur, body of pancreas, cardiac muscle tissue of right atrium, decidua, digastric muscle, gingival epithelium, islet of Langerhans, left ovary, molar, myocardium of left ventricle, retinal pigment epithelium, right auricle of heart, right ovary, right ventricle, sternocleidomastoid muscle, temporal muscle, vas deferens
RNA expression pattern · 19
VLDL receptor → ankle, biceps brachii, body of femur, body of pancreas, cardiac muscle tissue of right atrium, decidua, digastric muscle, gingival epithelium, islet of Langerhans, left ovary, molar, myocardium of left ventricle, retinal pigment epithelium, right auricle of heart, right ovary, right ventricle, sternocleidomastoid muscle, temporal muscle, vas deferens
Band · 2
VLDL receptor → 19 C1|19 21.77 cM, 9p24.2
Chr. · 2
VLDL receptor → Chromosome 19 (mouse), Chromosome 9 (human)
End · 2
VLDL receptor → 2,660,056 bp, 27,254,231 bp
Aliases · 1
VLDL receptor → VLDLR, CAMRQ1, CARMQ1, CHRMQ1, VLDLRCH, VLDL-R, very low density lipoprotein receptor
Available structures · 1
VLDL receptor → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V9U, 3DPR
BioGPS · 1
VLDL receptor → n/a
Databases · 1
VLDL receptor → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vldlr ldlr reelin gene lipoprotein receptor brain type expression found protein cholesterol exon ldl repeats role also lissencephaly cells heart

VLDL receptor relationships Subject–Predicate–Object triples

TTTA extracted 105 structured relationships around VLDL receptor. Examples in this analysis include VLDL receptor → Aliases → VLDLR, CAMRQ1, CARMQ1, CHRMQ1, VLDLRCH, VLDL-R, very low density lipoprotein receptor and VLDL receptor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V9U, 3DPR. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
VLDL receptorAliasesVLDLR, CAMRQ1, CARMQ1, CHRMQ1, VLDLRCH, VLDL-R, very low density lipoprotein receptor1.00infobox
VLDL receptorAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1V9U, 3DPR1.00infobox
VLDL receptorBand9p24.21.00infobox
VLDL receptorBand19 C1|19 21.77 cM1.00infobox
VLDL receptorBgeeright ventricle1.00infobox
VLDL receptorBgeeleft ovary1.00infobox
VLDL receptorBgeeright ovary1.00infobox
VLDL receptorBgeemyocardium of left ventricle1.00infobox
VLDL receptorBgeeislet of Langerhans1.00infobox
VLDL receptorBgeecardiac muscle tissue of right atrium1.00infobox
VLDL receptorBgeeright auricle of heart1.00infobox
VLDL receptorBgeegingival epithelium1.00infobox
VLDL receptorBgeebiceps brachii1.00infobox
VLDL receptorBgeebody of pancreas1.00infobox
VLDL receptorBgeedecidua1.00infobox
VLDL receptorBgeeretinal pigment epithelium1.00infobox
VLDL receptorBgeeankle1.00infobox
VLDL receptorBgeevas deferens1.00infobox
VLDL receptorBgeemolar1.00infobox
VLDL receptorBgeesternocleidomastoid muscle1.00infobox
VLDL receptorBgeedigastric muscle1.00infobox
VLDL receptorBgeebody of femur1.00infobox
VLDL receptorBgeetemporal muscle1.00infobox
VLDL receptorBioGPSn/a1.00infobox
VLDL receptorChr.Chromosome 9 (human)1.00infobox
VLDL receptorChr.Chromosome 19 (mouse)1.00infobox
VLDL receptorDatabasesNCBI: entry; OMA: entry1.00infobox
VLDL receptorEnd2,660,056 bp1.00infobox
VLDL receptorEnd27,254,231 bp1.00infobox
VLDL receptorEnsemblENSG000001478521.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around VLDL receptor bring nearby vocabulary together. In this analysis, examples include Family, Ldl and Lipoprotein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • VLDL receptor
    • Family
    • Ldl
    • Lipoprotein
    • Metabolism
    • Binding
    • Bp
    • Chr
    • Human
    • Found
    • Cerebellar
    • Endocytosis
    • Hypoplasia
  • vldl receptor
    • Family
    • Ldl
    • Lipoprotein
    • Metabolism
    • Binding
    • Bp
    • Chr
    • Human
    • Found
    • Cerebellar
    • Endocytosis
    • Hypoplasia
  • lipoprotein
    • Receptor
    • Ldl
    • Family
    • Metabolism
    • Bp
    • Chr
    • Human
    • Cerebellar
    • Hypoplasia
    • Process
    • Binding
    • Heart
  • low-density-lipoprotein (ldl) receptor family
    • Family
    • Ldl
    • Receptor
    • Lipoprotein
    • Repeats
    • Metabolism
    • Binding
    • Also
    • Bp
    • Chr
    • Human
    • Found
  • intermediate-density lipoprotein
    • Receptor
    • Ldl
    • Family
    • Metabolism
    • Bp
    • Chr
    • Human
    • Cerebellar
    • Hypoplasia
    • Process
    • Binding
    • Heart
  • ldl
    • Family
    • Receptor
    • Lipoprotein
    • Binding
    • Repeats
    • Bp
    • Chr
    • Human
    • Cerebellar
    • Endocytosis
    • Hypoplasia
    • Muscle
  • cholesterol
    • Metabolism
    • Pathway
    • Role
    • Receptor
    • Reelin
    • Bp
    • Chr
    • Human
    • Lipoproteins
    • Endocytosis
    • Muscle
    • Neuronal
  • lipoprotein a
    • Receptor
    • Ldl
    • Family
    • Metabolism
    • Bp
    • Chr
    • Human
    • Cerebellar
    • Hypoplasia
    • Process
    • Binding
    • Heart

Connections between topic areas Semantic bridges

For VLDL receptor, one of the stronger structural bridges in this analysis connects VLDL receptor with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
VLDL receptorOverview · splits 80 ⟂ 34
VLDL receptorTissue distribution and expression · splits 86 ⟂ 28
VLDL receptorAssociated disorders · splits 90 ⟂ 24
VLDL receptorProtein structure · splits 101 ⟂ 13
VLDL receptorLigand binding · splits 105 ⟂ 9
VLDL receptorFunction · splits 109 ⟂ 5

Map overview Semantic statistics

VLDL receptor

Nodes114
Edges113
Triples105
Avg. degree1.98
Density0.017544
Components1

Source & methodology

TTTA analyzes the structure around VLDL receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Tissue distribution and expression & Associated disorders, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — VLDL receptor · EN edition · Analysis: TopicsToTalkAbout

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