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T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene. This gene is also known by several other names: T-Brain 1, TBR-1, TES-56, and MGC141978. TBR1 is a member of the TBR1 subfamily of T-box family transcription factors, which share a common DNA-binding domain. Other members of the…
The analysis highlights Functions, Non-human orthologs and Gene regulation as prominent areas in the source structure around TBR1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TBR1 shows recurring relationship patterns in the source. For example, TBR1 → amygdala development, brain development, cerebral cortex development, commitment of neuronal cell to specific neuron type in forebrain, conditioned taste aversion, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, hindbrain development, identical protein binding, neuron differentiation, nucleus, positive regulation of transcription by RNA polymerase II, protein binding, protein kinase binding, regulation of axon guidance, regulation of gene expression, regulation of neuron projection development, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding Another extracted example is TBR1 → anterior cingulate cortex, Brodmann area 10, Brodmann area 9, CA3 field, cingulate gyrus, entorhinal cortex, frontal pole, ganglionic eminence, perirhinal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, superior frontal gyrus, testicle, visual cortex. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
expression gene neurons transcription brain protein development layer developing also cortex cortical t-box expressed found human vi genes factor mice
TTTA extracted 216 structured relationships around TBR1. Examples in this analysis include TBR1 → Aliases → TBR1, TBR-1, TES-56, T-box, brain 1, IDDAS, T-box brain transcription factor 1 and TBR1 → Band → 2q24.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TBR1 | Aliases | TBR1, TBR-1, TES-56, T-box, brain 1, IDDAS, T-box brain transcription factor 1 | 1.00 | infobox |
| TBR1 | Band | 2q24.2 | 1.00 | infobox |
| TBR1 | Band | 2 C1.3|2 35.56 cM | 1.00 | infobox |
| TBR1 | Bgee | ganglionic eminence | 1.00 | infobox |
| TBR1 | Bgee | Brodmann area 10 | 1.00 | infobox |
| TBR1 | Bgee | frontal pole | 1.00 | infobox |
| TBR1 | Bgee | Brodmann area 9 | 1.00 | infobox |
| TBR1 | Bgee | right frontal lobe | 1.00 | infobox |
| TBR1 | Bgee | cingulate gyrus | 1.00 | infobox |
| TBR1 | Bgee | anterior cingulate cortex | 1.00 | infobox |
| TBR1 | Bgee | postcentral gyrus | 1.00 | infobox |
| TBR1 | Bgee | superior frontal gyrus | 1.00 | infobox |
| TBR1 | Bgee | testicle | 1.00 | infobox |
| TBR1 | Bgee | perirhinal cortex | 1.00 | infobox |
| TBR1 | Bgee | piriform cortex | 1.00 | infobox |
| TBR1 | Bgee | primary motor cortex | 1.00 | infobox |
| TBR1 | Bgee | entorhinal cortex | 1.00 | infobox |
| TBR1 | Bgee | visual cortex | 1.00 | infobox |
| TBR1 | Bgee | primary visual cortex | 1.00 | infobox |
| TBR1 | Bgee | prefrontal cortex | 1.00 | infobox |
| TBR1 | Bgee | CA3 field | 1.00 | infobox |
| TBR1 | BioGPS | n/a | 1.00 | infobox |
| TBR1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| TBR1 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| TBR1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TBR1 | End | 161,425,870 bp | 1.00 | infobox |
| TBR1 | End | 61,644,458 bp | 1.00 | infobox |
| TBR1 | Ensembl | ENSG00000136535 | 1.00 | infobox |
| TBR1 | Entrez | 10716 | 1.00 | infobox |
| TBR1 | External IDs | OMIM: 604616; MGI: 107404; GeneCards: TBR1 | 1.00 | infobox |
The concept neighborhoods around TBR1 bring nearby vocabulary together. In this analysis, examples include Expression, Transcription and Neurons. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TBR1, one of the stronger structural bridges in this analysis connects TBR1 with Functions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TBR1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Functions, Non-human orthologs & Gene regulation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TBR1 · EN edition · Analysis: TopicsToTalkAbout