Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

CRKL: Interactions, Function & Overview

Crk-like protein is a protein that in humans is encoded by the CRKL gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

CRKL topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around CRKL.

Related topics
30
Source areas
3
Connected nodes
33
Extracted relationships
166
Concept neighborhoods
11
Bridge connections
33

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 23 topics
Function · 5 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CRKL, CRK like proto-oncogene, adaptor protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BZX, 2BZY, 2EO3, 2LQN, 2LQW
Band
22q11.21 · 16|16 A3
Bgee
secondary oocyte · ventricular zone · Brodmann area 10 · Skeletal muscle tissue of rectus abdominis · paraflocculus of cerebellum
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 16 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CRKL connects Entity context

The extracted context around CRKL shows recurring relationship patterns in the source. For example, CRKL → acetylcholine receptor signaling pathway, activation of GTPase activity, animal organ morphogenesis, anterior/posterior pattern specification, B cell apoptotic process, blood vessel development, cadherin binding, cell chemotaxis, cellular response to interleukin-7, cellular response to transforming growth factor beta stimulus, cerebellar neuron development, cerebral cortex development, cranial skeletal system development, cytokine-mediated signaling pathway, cytoplasm, cytosol, dendrite development, development of the heart, endosome, endothelin receptor signaling pathway Another extracted example is CRKL → amniotic fluid, Brodmann area 10, cerebellar vermis, embryo, fetal liver hematopoietic progenitor cell, ganglionic eminence, genital tubercle, internal carotid artery, internal globus pallidus, maxillary prominence, medial ganglionic eminence, paraflocculus of cerebellum, Rostral migratory stream, secondary oocyte, Skeletal muscle tissue of rectus abdominis, tail of embryo, tibiofemoral joint, ventricular zone, vestibular membrane of cochlear duct, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

CRKL

Top relations

Gene ontology · 69
CRKL → acetylcholine receptor signaling pathway, activation of GTPase activity, animal organ morphogenesis, anterior/posterior pattern specification, B cell apoptotic process, blood vessel development, cadherin binding, cell chemotaxis, cellular response to interleukin-7, cellular response to transforming growth factor beta stimulus, cerebellar neuron development, cerebral cortex development, cranial skeletal system development, cytokine-mediated signaling pathway, cytoplasm, cytosol, dendrite development, development of the heart, endosome, endothelin receptor signaling pathway
Bgee · 20
CRKL → amniotic fluid, Brodmann area 10, cerebellar vermis, embryo, fetal liver hematopoietic progenitor cell, ganglionic eminence, genital tubercle, internal carotid artery, internal globus pallidus, maxillary prominence, medial ganglionic eminence, paraflocculus of cerebellum, Rostral migratory stream, secondary oocyte, Skeletal muscle tissue of rectus abdominis, tail of embryo, tibiofemoral joint, ventricular zone, vestibular membrane of cochlear duct, zygote
RNA expression pattern · 20
CRKL → amniotic fluid, Brodmann area 10, cerebellar vermis, embryo, fetal liver hematopoietic progenitor cell, ganglionic eminence, genital tubercle, internal carotid artery, internal globus pallidus, maxillary prominence, medial ganglionic eminence, paraflocculus of cerebellum, Rostral migratory stream, secondary oocyte, Skeletal muscle tissue of rectus abdominis, tail of embryo, tibiofemoral joint, ventricular zone, vestibular membrane of cochlear duct, zygote
related to Interactions · 20
CRKL → Abl, BCAR1, BCR, Cbl, CBLB, CD117, CD34, Dock2, EPOR, GAB1, GAB2, INPP5D, MAP4K1, MAP4K5, NEDD9, PaxillinRAPGEF1, PIK3R2, RICS, STAT5A, Syk
related to Function · 12
CRKL → BCR-ABL, CRK, CT10-homolog-like, DAB1, In, It, JUN, RAS, RAS-dependent, Reelin, SH2, SH3
Band · 2
CRKL → 16|16 A3, 22q11.21
Chr. · 2
CRKL → Chromosome 16 (mouse), Chromosome 22 (human)
End · 2
CRKL → 17,305,298 bp, 20,953,747 bp
related to External links · 2
CRKL → Human CRKL, UCSC Genome Browser
Aliases · 1
CRKL → CRKL, CRK like proto-oncogene, adaptor protein

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene human chr band chromosome 22 location protein crk mouse signaling function external search 953 747 end 20 16

CRKL relationships Subject–Predicate–Object triples

TTTA extracted 166 structured relationships around CRKL. Examples in this analysis include CRKL → Aliases → CRKL, CRK like proto-oncogene, adaptor protein and CRKL → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BZX, 2BZY, 2EO3, 2LQN, 2LQW. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CRKLAliasesCRKL, CRK like proto-oncogene, adaptor protein1.00infobox
CRKLAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BZX, 2BZY, 2EO3, 2LQN, 2LQW1.00infobox
CRKLBand22q11.211.00infobox
CRKLBand16|16 A31.00infobox
CRKLBgeesecondary oocyte1.00infobox
CRKLBgeeventricular zone1.00infobox
CRKLBgeeBrodmann area 101.00infobox
CRKLBgeeSkeletal muscle tissue of rectus abdominis1.00infobox
CRKLBgeeparaflocculus of cerebellum1.00infobox
CRKLBgeeinternal globus pallidus1.00infobox
CRKLBgeeembryo1.00infobox
CRKLBgeeganglionic eminence1.00infobox
CRKLBgeeamniotic fluid1.00infobox
CRKLBgeecerebellar vermis1.00infobox
CRKLBgeeRostral migratory stream1.00infobox
CRKLBgeetail of embryo1.00infobox
CRKLBgeemedial ganglionic eminence1.00infobox
CRKLBgeetibiofemoral joint1.00infobox
CRKLBgeeinternal carotid artery1.00infobox
CRKLBgeegenital tubercle1.00infobox
CRKLBgeevestibular membrane of cochlear duct1.00infobox
CRKLBgeezygote1.00infobox
CRKLBgeefetal liver hematopoietic progenitor cell1.00infobox
CRKLBgeemaxillary prominence1.00infobox
CRKLBioGPSMore reference expression data1.00infobox
CRKLChr.Chromosome 22 (human)1.00infobox
CRKLChr.Chromosome 16 (mouse)1.00infobox
CRKLDatabasesNCBI: entry; OMA: entry1.00infobox
CRKLEnd20,953,747 bp1.00infobox
CRKLEnd17,305,298 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CRKL bring nearby vocabulary together. In this analysis, examples include Gene, Crk and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CRKL
    • Gene
    • Crk
    • Protein
    • Signaling
    • Location
    • Human
    • Cascade
    • Function
    • Ras
    • Search
    • Shown
    • Ucsc
  • crkl
    • Gene
    • Crk
    • Protein
    • Signaling
    • Location
    • Human
    • Cascade
    • Function
    • Ras
    • Search
    • Shown
    • Ucsc
  • crkl gene
    • Location
    • Human
    • Gene
    • Protein
    • Chromosome
    • Bp
    • Chr
    • Crk
    • Signaling
    • End
    • Function
    • Mouse
  • abl gene
    • Location
    • Human
    • Protein
    • Chromosome
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Search
    • Ucsc
    • Crk
  • bcr gene
    • Location
    • Human
    • Protein
    • Chromosome
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Search
    • Ucsc
    • Crk
  • cbl gene
    • Location
    • Human
    • Protein
    • Chromosome
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Search
    • Ucsc
    • Crk
  • function
    • Search
    • Protein
    • Also
    • Chromosome
    • External
    • Interactions
    • Links
    • Location
    • Reading
    • References
    • See
    • Bp
  • protein
    • Search
    • Location
    • Reading
    • References
    • See
    • Cascade
    • End
    • Fibroblast
    • Mouse
    • Ras
    • Substrate
    • Ucsc

Connections between topic areas Semantic bridges

For CRKL, one of the stronger structural bridges in this analysis connects CRKL with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CRKLInteractions · splits 10 ⟂ 24
CRKLFunction · splits 28 ⟂ 6
CRKLOverview · splits 31 ⟂ 3

Map overview Semantic statistics

CRKL

Nodes34
Edges33
Triples166
Avg. degree1.94
Density0.058824
Components1

Source & methodology

TTTA analyzes the structure around CRKL to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CRKL · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.