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GRIN2B

Glutamate Receptor Ionotropic subunit epsilon-2, also known as N-methyl D-aspartate receptor subtype 2B (NMDAR2B or NR2B), is a protein that in humans is encoded by the GRIN2B gene.

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Aliases
GRIN2B, GluN2B, MRD6, NMDAR2B, NR2B, hNR3, EIEE27, glutamate ionotropic receptor NMDA type subunit 2B, NR3, DEE27
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EWM, 5EWL, 5EWJ
Band
12p13.1 · 6 G1|6 66.38 cM
Bgee
buccal mucosa cell · Brodmann area 23 · sural nerve · middle temporal gyrus · primary visual cortex
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 6 (mouse)

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Overview

NMDA receptors

Function

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Interactions

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Map overview Semantic statistics

GRIN2B

Nodes42
Edges41
Triples137
Avg. degree1.95
Density0.047619
Components1

How this topic connects Entity context

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GRIN2B

Top relations

Gene ontology · 51
GRIN2B → amyloid-beta binding, brain development, calcium ion transmembrane import into cytosol, calcium-mediated signaling, cell junction, cell surface, chemical synaptic transmission, cytoplasm, ephrin receptor signaling pathway, excitatory chemical synaptic transmission, excitatory postsynaptic potential, extracellularly glutamate-gated ion channel activity, glutamate binding, glutamate receptor signaling pathway, glutamate-gated calcium ion channel activity, glycine binding, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, ion channel activity
Bgee · 18
GRIN2B → anterior amygdaloid area, Brodmann area 23, buccal mucosa cell, corpus callosum, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, endothelial cell, lateral geniculate nucleus, lateral septal nucleus, middle temporal gyrus, nucleus accumbens, olfactory tubercle, prefrontal cortex, primary visual cortex, seminiferous tubule, subiculum, superior frontal gyrus, sural nerve
RNA expression pattern · 18
GRIN2B → anterior amygdaloid area, Brodmann area 23, buccal mucosa cell, corpus callosum, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, endothelial cell, lateral geniculate nucleus, lateral septal nucleus, middle temporal gyrus, nucleus accumbens, olfactory tubercle, prefrontal cortex, primary visual cortex, seminiferous tubule, subiculum, superior frontal gyrus, sural nerve
related to NMDA receptors · 14
GRIN2B → GRIN1, GRIN2A, GRIN2C, GRIN2D, N-Methyl-D-aspartate, NMDA, NMDAR1, NMDAR2, NMDAR2A, NMDAR2B, NMDAR2C, NMDAR2D, The NMDA, The NR2
related to Function · 7
GRIN2B → Doogie, Engineered, LTP, NR2B, NR2B/NR2A, The, This
related to Interactions · 6
GRIN2B → Actinin, DLG2, DLG3, DLG4, EXOC4, LIN7B
Band · 2
GRIN2B → 12p13.1, 6 G1|6 66.38 cM
Chr. · 2
GRIN2B → Chromosome 12 (human), Chromosome 6 (mouse)
End · 2
GRIN2B → 13,982,002 bp, 136,150,509 bp
Aliases · 1
GRIN2B → GRIN2B, GluN2B, MRD6, NMDAR2B, NR2B, hNR3, EIEE27, glutamate ionotropic receptor NMDA type subunit 2B, NR3, DEE27

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Important terminology

nmda receptor glutamate bp chr human band gene nr2b ionotropic chromosome 12 subunit function also mouse nmdar2b location protein receptors

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GRIN2BAliasesGRIN2B, GluN2B, MRD6, NMDAR2B, NR2B, hNR3, EIEE27, glutamate ionotropic receptor NMDA type subunit 2B, NR3, DEE271.00infobox
GRIN2BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EWM, 5EWL, 5EWJ1.00infobox
GRIN2BBand12p13.11.00infobox
GRIN2BBand6 G1|6 66.38 cM1.00infobox
GRIN2BBgeebuccal mucosa cell1.00infobox
GRIN2BBgeeBrodmann area 231.00infobox
GRIN2BBgeesural nerve1.00infobox
GRIN2BBgeemiddle temporal gyrus1.00infobox
GRIN2BBgeeprimary visual cortex1.00infobox
GRIN2BBgeecorpus callosum1.00infobox
GRIN2BBgeeprefrontal cortex1.00infobox
GRIN2BBgeenucleus accumbens1.00infobox
GRIN2BBgeeendothelial cell1.00infobox
GRIN2BBgeedorsolateral prefrontal cortex1.00infobox
GRIN2BBgeelateral septal nucleus1.00infobox
GRIN2BBgeeolfactory tubercle1.00infobox
GRIN2BBgeelateral geniculate nucleus1.00infobox
GRIN2BBgeedentate gyrus of hippocampal formation granule cell1.00infobox
GRIN2BBgeeanterior amygdaloid area1.00infobox
GRIN2BBgeesuperior frontal gyrus1.00infobox
GRIN2BBgeesubiculum1.00infobox
GRIN2BBgeeseminiferous tubule1.00infobox
GRIN2BBioGPSMore reference expression data1.00infobox
GRIN2BChr.Chromosome 12 (human)1.00infobox
GRIN2BChr.Chromosome 6 (mouse)1.00infobox
GRIN2BDatabasesNCBI: entry; OMA: entry1.00infobox
GRIN2BEnd13,982,002 bp1.00infobox
GRIN2BEnd136,150,509 bp1.00infobox
GRIN2BEnsemblENSG000002730791.00infobox
GRIN2BEntrez29041.00infobox

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