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NPAS3 or Neuronal PAS domain protein 3 is a brain-enriched transcription factor belonging to the bHLH-PAS superfamily of transcription factors, the members of which carry out diverse functions, including circadian oscillations, neurogenesis, toxin metabolism, hypoxia, and tracheal development. NPAS3 contains a basic helix-loop-helix structural motif and…
The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around NPAS3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around NPAS3 shows recurring relationship patterns in the source. For example, NPAS3 → buccal mucosa cell, condyle, corpus callosum, deep cerebellar nuclei, dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, endothelial cell, entorhinal cortex, external globus pallidus, fossa, globus pallidus, inferior ganglion of vagus nerve, internal globus pallidus, lateral hypothalamus, lumbar subsegment of spinal cord, optic nerve, substantia nigra, ventral tegmental area, ventricular zone Another extracted example is NPAS3 → cytosol, developmental process, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein dimerization activity, protein heterodimerization activity, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, transcription, DNA-templated. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
human bp gene chr band chromosome 14 superfamily pas domain schizophrenia protein mouse location function bhlh-pas functions neuronal transcription factor
TTTA extracted 86 structured relationships around NPAS3. Examples in this analysis include NPAS3 → Aliases → NPAS3, neuronal PAS domain protein 3, MOP6, PASD6, bHLHe12 and NPAS3 → Band → 14q13.1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NPAS3 | Aliases | NPAS3, neuronal PAS domain protein 3, MOP6, PASD6, bHLHe12 | 1.00 | infobox |
| NPAS3 | Band | 14q13.1 | 1.00 | infobox |
| NPAS3 | Band | 12|12 C1 | 1.00 | infobox |
| NPAS3 | Bgee | endothelial cell | 1.00 | infobox |
| NPAS3 | Bgee | ventricular zone | 1.00 | infobox |
| NPAS3 | Bgee | corpus callosum | 1.00 | infobox |
| NPAS3 | Bgee | buccal mucosa cell | 1.00 | infobox |
| NPAS3 | Bgee | globus pallidus | 1.00 | infobox |
| NPAS3 | Bgee | internal globus pallidus | 1.00 | infobox |
| NPAS3 | Bgee | external globus pallidus | 1.00 | infobox |
| NPAS3 | Bgee | optic nerve | 1.00 | infobox |
| NPAS3 | Bgee | inferior ganglion of vagus nerve | 1.00 | infobox |
| NPAS3 | Bgee | entorhinal cortex | 1.00 | infobox |
| NPAS3 | Bgee | substantia nigra | 1.00 | infobox |
| NPAS3 | Bgee | lumbar subsegment of spinal cord | 1.00 | infobox |
| NPAS3 | Bgee | deep cerebellar nuclei | 1.00 | infobox |
| NPAS3 | Bgee | dorsal tegmental nucleus | 1.00 | infobox |
| NPAS3 | Bgee | fossa | 1.00 | infobox |
| NPAS3 | Bgee | dorsomedial hypothalamic nucleus | 1.00 | infobox |
| NPAS3 | Bgee | ventral tegmental area | 1.00 | infobox |
| NPAS3 | Bgee | condyle | 1.00 | infobox |
| NPAS3 | Bgee | lateral hypothalamus | 1.00 | infobox |
| NPAS3 | BioGPS | n/a | 1.00 | infobox |
| NPAS3 | Chr. | Chromosome 14 (human) | 1.00 | infobox |
| NPAS3 | Chr. | Chromosome 12 (mouse) | 1.00 | infobox |
| NPAS3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| NPAS3 | End | 33,820,863 bp | 1.00 | infobox |
| NPAS3 | End | 54,072,175 bp | 1.00 | infobox |
| NPAS3 | Ensembl | ENSG00000151322 | 1.00 | infobox |
| NPAS3 | Entrez | 64067 | 1.00 | infobox |
The concept neighborhoods around NPAS3 bring nearby vocabulary together. In this analysis, examples include Gene, Human and Domain. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For NPAS3, one of the stronger structural bridges in this analysis connects NPAS3 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around NPAS3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — NPAS3 · EN edition · Analysis: TopicsToTalkAbout