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Subventricular zone

The subventricular zone (SVZ) is a region situated on the outside wall of each lateral ventricle of the vertebrate brain. It is present in both the embryonic and adult brain. In embryonic life, the SVZ refers to a secondary proliferative zone containing neural progenitor cells, which divide to produce neurons in the process of neurogenesis. The primary…

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NeuroLex ID
nlx_144262

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Subventricular zone

Nodes96
Edges95
Triples46
Avg. degree1.98
Density0.020833
Components1

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Subventricular zone

Top relations

related to Function · 14
Subventricular zone → Along, For, In, It, Lewis, Notch, NPCs, NSCs, SVZ, The, The SVZ, This, While, With
related to Role of neuropeptide Y in neurogenesis · 13
Subventricular zone → Along, As NPY, BrdU, DCX, Decressac, GABA, However, Identification, In, NPY, Such, The, Y1
related to As a potential source of brain tumors · 7
Subventricular zone → BTSCs, In, It, NSCs, Quinones-Hinojosa, Several, These
NeuroLex ID · 1
Subventricular zone → nlx_144262

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Important terminology

svz brain cells cell neurogenesis stem neural adult zone neuronal proliferation layer also astrocytes neurons yet citation needed found injury

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Subventricular zoneNeuroLex IDnlx_1442621.00infobox
tenascin-Cinstance ofas well as extracellular matrix components0.80text
the tested NPYinstance ofThis natural molecular regulation of adult neurogenesis would be adjunct with therapies of appropriate molecules0.80text
Y1 receptorinstance ofThis natural molecular regulation of adult neurogenesis would be adjunct with therapies of appropriate molecules0.80text
in addition to pharmacological derivativesinstance ofThis natural molecular regulation of adult neurogenesis would be adjunct with therapies of appropriate molecules0.80text
in providing for manageable forms of neurodegenerative disorders of the striatal areainstance ofThis natural molecular regulation of adult neurogenesis would be adjunct with therapies of appropriate molecules0.80text
leukemiainstance ofIt was therefore proposed that a small population of BTSCs with such self-renewal capabilities were maintaining tumors in diseases0.80text
breast cancerinstance ofIt was therefore proposed that a small population of BTSCs with such self-renewal capabilities were maintaining tumors in diseases0.80text
gliomasinstance ofWhile it remains to be definitely proven whether the SVZ stem cells are the cell of origin for brain tumors0.80text
there is strong evidence that suggests increased tumor aggressivenessinstance ofWhile it remains to be definitely proven whether the SVZ stem cells are the cell of origin for brain tumors0.80text
mortality in those patients whose high-grade gliomas infiltrate or contact the SVZ.In prostate cancerinstance ofWhile it remains to be definitely proven whether the SVZ stem cells are the cell of origin for brain tumors0.80text
tumor-induced neurogenesis is characterized by the recruitment of neural progenitor cellsinstance ofWhile it remains to be definitely proven whether the SVZ stem cells are the cell of origin for brain tumors0.80text

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