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The subgranular zone (SGZ) is a layer of cells in the dentate gyrus, in the hippocampal formation, which is a site of adult neurogenesis in the brain.
Structure, Hippocampal neurogenesis & Clinical significance
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cells neurogenesis sgz cell neurons stem astrocytes also radial neural brain glial layer hippocampal granule proliferation new memory learning development
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Subgranular zone | is a | narrow layer of cells located between the granule cell layer and hilus of the dentate gyrus | 0.90 | text |
| memory | instance of | which are thought to contribute to cognitive functions | 0.80 | text |
| learning | instance of | which are thought to contribute to cognitive functions | 0.80 | text |
| GFAP | instance of | their expression of glial markers | 0.80 | text |
| and their function in regulating the NSC microenvironment | instance of | their expression of glial markers | 0.80 | text |
| nestin | instance of | cells in this category may initially express glial markers like GFAP and stem cell markers | 0.80 | text |
| Sox2 | instance of | cells in this category may initially express glial markers like GFAP and stem cell markers | 0.80 | text |
| but eventually | instance of | cells in this category may initially express glial markers like GFAP and stem cell markers | 0.80 | text |
| they lose these characteristics | instance of | cells in this category may initially express glial markers like GFAP and stem cell markers | 0.80 | text |
| begin expressing markers specific to granule cells such as NeuroD | instance of | cells in this category may initially express glial markers like GFAP and stem cell markers | 0.80 | text |
| Prox1 | instance of | cells in this category may initially express glial markers like GFAP and stem cell markers | 0.80 | text |
| vascular endothelial growth factor | instance of | provide attachment points for neurogenic cells and release diffusible signals | 0.80 | text |
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