Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Glutamate decarboxylase

Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide (.mw-parser-output .template-chem2-su{display:inline-block;font-size:80%;line-height:1;vertical-align:-0.35em}.mw-parser-output…

Role in pathology, Overview & Other anti-GAD-associated neurologic disorders

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Glutamate decarboxylase. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA
enzyme data
CAS no.
9024-58-2m
EC no.
4.1.1.15
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure and mechanism

Regulation of GAD65 and GAD67

Role in the nervous system

Role in pathology

Other anti-GAD-associated neurologic disorders

Role of glutamate decarboxylase in other organisms

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Glutamate decarboxylase

Nodes67
Edges66
Triples51
Avg. degree1.97
Density0.029851
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Glutamate decarboxylase

Top relations

related to Role of glutamate decarboxylase in other organisms · 22
Glutamate decarboxylase → Besides, Binding, C-terminus, Ca2, CaM, CAM-binding, CAM-independent GAD, CaMBD, Finally, GABA, GAD, In Citrus, In Saccharomyces, Interesting, It, Similarly, The C-terminus, This, Unlike, When GAD
related to External links · 15
Glutamate decarboxylase → Deficits, Expression Profiling Support GABA, Glutamate, June, Media, Overview, PDB, PDBe-KB, Q05329, Q99259, Schizophrenia, Schizophrenia Research Forum, UniProt, Wikimedia CommonsGenetics, Wiktionary-logo-en-v2
BRENDA · 1
Glutamate decarboxylase → enzyme data
CAS no. · 1
Glutamate decarboxylase → 9024-58-2m
EC no. · 1
Glutamate decarboxylase → 4.1.1.15
ExPASy · 1
Glutamate decarboxylase → NiceZyme view
Gene Ontology · 1
Glutamate decarboxylase → AmiGO / QuickGO
KEGG · 1
Glutamate decarboxylase → enzyme entry
MetaCyc · 1
Glutamate decarboxylase → metabolic pathway
NCBI · 1
Glutamate decarboxylase → proteins

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gad65 gad67 gaba gad also decarboxylase glutamate isoforms plp schizophrenia levels acid two enzyme diabetes brain type coli regulated cam

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Glutamate decarboxylaseBRENDAenzyme data1.00infobox
Glutamate decarboxylaseCAS no.9024-58-2m1.00infobox
Glutamate decarboxylaseEC no.4.1.1.151.00infobox
Glutamate decarboxylaseExPASyNiceZyme view1.00infobox
Glutamate decarboxylaseGene OntologyAmiGO / QuickGO1.00infobox
Glutamate decarboxylaseKEGGenzyme entry1.00infobox
Glutamate decarboxylaseMetaCycmetabolic pathway1.00infobox
Glutamate decarboxylaseNCBIproteins1.00infobox
Glutamate decarboxylasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
Glutamate decarboxylasePMCarticles1.00infobox
Glutamate decarboxylasePubMedarticles1.00infobox
Glutamate decarboxylaseRheareactions1.00infobox
Glutamate decarboxylaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.