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Vitamin B12

Vitamin B12, also known as cobalamin or extrinsic factor, is a water-soluble vitamin involved in metabolism. One of eight B vitamins, it serves as a vital cofactor in DNA synthesis and both fatty acid and amino acid metabolism. It plays an essential role in the nervous system by supporting myelin synthesis and is critical for the maturation of red blood…

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B03BA01 (WHO)
Bioavailability
Readily absorbed in the distal half of the ileum.
CAS Number
68-19-9
ChEMBL
ChEMBL2110563

Topics to explore

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Overview

Definition

Deficiency

Medical uses

Dietary recommendations

Sources

Drug interactions

Chemistry

Biochemistry

Physiology

Synthesis

History

Society and culture

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Map overview Semantic statistics

Vitamin B12

Nodes321
Edges320
Triples357
Avg. degree1.99
Density0.006231
Components1

How this topic connects Entity context

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Vitamin B12

Top relations

related to Identification of the active compound · 32
Vitamin B12 → Agriculture, Alexander, B12, Bureau, Cambridge, Chemistry, Dairy Industry, Department, Dorner, Dorothy Hodgkin, Folker, George Minot, George Whipple, Hodgkin, In, Karl Folkers, Lactobacillus, LLD, Mary Shaw Shorb, Maryland
related to Biosynthesis · 29
Vitamin B12 → Acetobacterium, Aerobacter, Agrobacterium, Alcaligenes, Azotobacter, B12, Bacillus, Clostridium, Corynebacterium, Flavobacterium, III, It, Lactobacillus, Later, Micromonospora, Mycobacterium, Nocardia, Propionibacterium, Proteus, Pseudomonas
related to Dietary recommendations · 27
Vitamin B12 → AI, AIs, As, B12, Because, Children, Collectively, DRIs, EAR, EARs, For, Grain-based, However, In, Medicine, Pharmaceutical, RDA, RDAs, Since, Some
related to Diagnosis · 16
Vitamin B12 → According, At, B12, Diagnosis, For, However, If, II, In, MCV, MMA, Serum, Several, The, Therefore, This
related to Pregnancy, lactation, and early childhood · 15
Vitamin B12 → AI, As, B12, Determination, During, EFSA, European Food Safety Authority, However, Low, RDA, Recommended Dietary Allowance, The, This, Women, World Health Organization
has method · 12
Vitamin B12 → ATCC7830, B12, B12-requiring, Currently, Furthermore, However, IF, Lactobacillus, Previous, RIDA, Several, The
related to Chemistry · 12
Vitamin B12 → Animals, As, B12, B12r, B12s, Biochemically, CH3, CN, Four, Historically, OH, The
related to Identification of liver as an anti-anemia food · 12
Vitamin B12 → B12, During, Edwin Cohn, George Minot, George Whipple, In, Medicine, Murphy, Nobel Prize, Physiology, William, William Castle
related to Industrial · 12
Vitamin B12 → B12, Drug Administration, Food, GRAS, Industrial, Propionibacterium, Pseudomonas, Rhone-Poulenc, Streptomyces, The, These, United States
related to Society and culture · 12
Vitamin B12 → After, B12, Baltimore, Healthcare, However, In, John, Mayo Clinic, Myers, The, There, This

Important terminology Word statistics

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Important terminology

b12 vitamin deficiency may anemia also food cyanocobalamin dietary liver μg foods absorption acid bacteria levels risk synthesis used fermentation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Vitamin B123D model (JSmol)Interactive image1.00infobox
Vitamin B12AHFS/Drugs.comMonograph1.00infobox
Vitamin B12ATC codeB03BA01 (WHO)1.00infobox
Vitamin B12BioavailabilityReadily absorbed in the distal half of the ileum.1.00infobox
Vitamin B12CAS Number68-19-91.00infobox
Vitamin B12ChEMBLChEMBL21105631.00infobox
Vitamin B12ChemSpider104695041.00infobox
Vitamin B12DrugBankDB001151.00infobox
Vitamin B12Elimination half-lifeApproximately 6 days (400 days in the liver).1.00infobox
Vitamin B12ExcretionKidney1.00infobox
Vitamin B12FormulaC63H88CoN14O14P1.00infobox
Vitamin B12KEGGD001661.00infobox
Vitamin B12Legal statusUK: OTC1.00infobox
Vitamin B12Legal statusUS: OTC1.00infobox
Vitamin B12License dataUS DailyMed: Vitamin_b121.00infobox
Vitamin B12MedlinePlusa6050071.00infobox
Vitamin B12MetabolismLiver1.00infobox
Vitamin B12Molar mass1355.388 g·mol−11.00infobox
Vitamin B12Other namesVitamin B12, vitamin B-12, cobalamin1.00infobox
Vitamin B12Protein bindingVery high to specific transcobalamins plasma proteins. Binding of hydroxocobalamin is slightly higher than cyanocobalamin.1.00infobox
Vitamin B12PubChem CID1849331.00infobox
Vitamin B12Routes of administrationBy mouth, sublingual, intravenous (IV), intramuscular (IM), intranasal1.00infobox
Vitamin B12UNIIP6YC3EG2041.00infobox
Vitamin B12is amost chemically complex of all vitamins0.90text

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