Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Heme: Function, Types & Degradation

Heme (American English), or haem (Commonwealth English, both pronounced /hi:m/ HEEM), is a ring-shaped iron-containing molecule that serves as a ligand of various proteins, especially as a component of hemoglobin, which carries oxygen in the bloodstream. It is composed of four pyrrole rings with two vinyl and two propionic acid side chains. Heme is…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Heme topic overview

The analysis highlights Function, Types and Degradation as prominent areas in the source structure around Heme.

Related topics
156
Source areas
8
Connected nodes
164
Extracted relationships
75
Related term clusters
44
Bridge connections
164

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 40 topics
Function · 26 topics
Degradation · 25 topics
Types · 20 topics
Synthesis · 17 topics
Genes · 14 topics
In health and disease · 9 topics
Synthesis for food · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Types

Synthesis

Synthesis for food

Degradation

In health and disease

Genes

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Heme connects Entity context

The extracted context around Heme shows recurring relationship patterns in the source. For example, Heme → ALAD, ALAS1, CPOX, FECH, HMBS, III, PPOX, UROD, UROS Another extracted example is Heme → German, Hans Fischer, IUPAC, Lactoperoxidase, Myeloperoxidase, Ring III, Similar, Thyroid. Use these groups to spot repeated connection types before inspecting the individual relationships.

Heme

Top relations

related to Genes · 9
Heme → ALAD, ALAS1, CPOX, FECH, HMBS, III, PPOX, UROD, UROS
related to Other hemes · 8
Heme → German, Hans Fischer, IUPAC, Lactoperoxidase, Myeloperoxidase, Ring III, Similar, Thyroid
related to Use of capital letters to designate the type of heme · 8
Heme → Caughey, Caughey's, Cytochrome, Lowercase, Puustinen, Thus, Wikstrom, York
related to Cancer · 7
Heme → AICR, Cancer Research, International, N-nitroso, The American Institute, WCRF, World Cancer Research Fund
related to Synthesis · 7
Heme → ALA, ALAs, B12, CoA, F430, Krebs, Mechanism
related to Degradation · 5
Heme → CO, Degradation, Fe2, HO, NADPH
related to Function · 5
Heme → Fe, Hemoproteins, II, III, IV
related to In health and disease · 4
Heme → DNA, Due, Fenton's, IX
related to Synthesis for food · 3
Heme → Impossible, Impossible Foods, The DNA
related to Major hemes · 2
Heme → Cytochrome, Isolated

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

oxygen hemoglobin iron molecule hemoproteins peroxidase synthesis hemes synthase acid cytochrome liver protein enzyme process groups used also important two

Heme relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around Heme. Examples in this analysis include Heme → is a → coordination complex and myoglobin → instance of → but are also found in a number of other biologically important hemoproteins. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Hemeis acoordination complex0.90text
myoglobininstance ofbut are also found in a number of other biologically important hemoproteins0.80text
cytochromesinstance ofbut are also found in a number of other biologically important hemoproteins0.80text
catalasesinstance ofbut are also found in a number of other biologically important hemoproteins0.80text
heme peroxidaseinstance ofbut are also found in a number of other biologically important hemoproteins0.80text
and endothelial nitric oxide synthase.The word haem is derivedinstance ofbut are also found in a number of other biologically important hemoproteins0.80text
from Ancient Greekinstance ofbut are also found in a number of other biologically important hemoproteins0.80text
αἷμαinstance ofbut are also found in a number of other biologically important hemoproteins0.80text
cofactor F430instance ofit also produces more complex substances0.80text
cobalamininstance ofit also produces more complex substances0.80text
Hemopexininstance ofproteins0.80text
meatlessinstance ofadding the resulting heme to items0.80text

Related concept clusters Related term clusters

The concept neighborhoods around Heme bring nearby vocabulary together. In this analysis, examples include Iron, Cytochrome and Hemes. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Heme
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic
  • heme
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic
  • heme peroxidase
    • Lactoperoxidase
    • Iron
    • Reactions
    • Serves
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Bacteria
    • Synthase
    • Two
    • Responsible
  • heme b
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic
  • heme a
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic
  • heme c
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic
  • heme oxygenase
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic
  • heme oxygenase-1
    • Iron
    • Cytochrome
    • Hemes
    • Hemoglobin
    • Synthesis
    • Free
    • Group
    • Groups
    • Hemoproteins
    • Protein
    • Oxygen
    • Diatomic

Connections between topic areas Semantic bridges

For Heme, one of the stronger structural bridges in this analysis connects Heme with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Heme — Overview · splits 124 ⟂ 41
Heme — Function · splits 138 ⟂ 27
Heme — Degradation · splits 139 ⟂ 26
Heme — Types · splits 144 ⟂ 21
Heme — Synthesis · splits 147 ⟂ 18
Heme — Genes · splits 150 ⟂ 15
Heme — In health and disease · splits 155 ⟂ 10
Heme — Synthesis for food · splits 159 ⟂ 6

Map overview Semantic statistics

Heme

Nodes165
Edges164
Triples75
Avg. degree1.99
Density0.012121
Components1

Source & methodology

TTTA analyzes the structure around Heme to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Types & Degradation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Heme · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.

Monitor your Domain Rating with FrogDR