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Erythromycin

Erythromycin (sometimes abbreviated ETM in reports) is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used during pregnancy to prevent Group B streptococcal infection in the newborn, and…

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
D10AF02 (WHO) J01FA01 (WHO) S01AA17 (WHO) QJ51FA01 (WHO)
Bioavailability
Depends on the ester type; between 30% and 65%
CAS Number
114-07-8 Y
ChEBI
CHEBI:42355 Y
ChEMBL
ChEMBL532 Y

Topics to explore

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Overview

Medical uses

Adverse effects

Interactions

Pharmacology

Chemistry

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Erythromycin

Nodes110
Edges109
Triples106
Avg. degree1.98
Density0.018182
Components1

How this topic connects Entity context

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Erythromycin

Top relations

related to Interactions · 19
Erythromycin → Another, CYP3A, CYP3A4, Earlier, Hence, Hismanal, If, Interactions, Lipitor, Mevacor, Orap, Other, P450, Propulsid, QT, Seldane, Seldane-D, The, Zocor
related to history · 13
Erythromycin → Abelardo, Aguilar, Beesley, Company, Eli Lilly, Eugene, Filipino, In, Indiana, Indianapolis, Saccharopolyspora, Streptomyces, The
has effect · 7
Erythromycin → Allergic, Cholestasis, Gastrointestinal, Johnson, More, QT, Stevens
related to Metabolism · 7
Erythromycin → Absorption, CYP3A4, Erythromycin's, Its, Most, Pediatrics, The American Association
related to Medical uses · 6
Erythromycin → Corynebacterium, Haemophilus, MIC, Staphylococcus, Streptococcus, The
related to Composition · 4
Erythromycin → Each, Erythromycins, Some, Standard-grade
related to Mechanism of action · 4
Erythromycin → By, It, This, Without
related to Synthesis · 4
Erythromycin → Complete, Over, The, Woodward
Legal status · 3
Erythromycin → AU: S4 (Prescription only), UK: POM (Prescription only), US: ℞-only
is a · 2
Erythromycin → inhibitor of the cytochrome P450 system, motilin agonist.More serious side effects include arrhythmia with prolonged QT intervals

Important terminology Word statistics

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Important terminology

also may used effects drugs pregnancy bacteria drug bacterial include infections safe aguilar side metabolism liver levels price given qt

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ErythromycinAHFS/Drugs.comMonograph1.00infobox
ErythromycinATC codeD10AF02 (WHO) J01FA01 (WHO) S01AA17 (WHO) QJ51FA01 (WHO)1.00infobox
ErythromycinBioavailabilityDepends on the ester type; between 30% and 65%1.00infobox
ErythromycinCAS Number114-07-8 Y1.00infobox
ErythromycinChEBICHEBI:42355 Y1.00infobox
ErythromycinChEMBLChEMBL532 Y1.00infobox
ErythromycinChemSpider12041 Y1.00infobox
ErythromycinCompTox Dashboard (EPA)DTXSID40229911.00infobox
ErythromycinDrug classMacrolide antibiotic1.00infobox
ErythromycinDrugBankDB00199 Y1.00infobox
ErythromycinECHA InfoCard100.003.6731.00infobox
ErythromycinElimination half-life1.5 hours1.00infobox
ErythromycinExcretionBile1.00infobox
ErythromycinFormulaC37H67NO131.00infobox
ErythromycinIUPHAR/BPS14561.00infobox
ErythromycinKEGGD00140 Y1.00infobox
ErythromycinLegal statusAU: S4 (Prescription only)1.00infobox
ErythromycinLegal statusUK: POM (Prescription only)1.00infobox
ErythromycinLegal statusUS: ℞-only1.00infobox
ErythromycinLicense dataUS DailyMed: Erythromycin1.00infobox
ErythromycinMedlinePlusa6823811.00infobox
ErythromycinMetabolismLiver (under 5% excreted unchanged)1.00infobox
ErythromycinMolar mass733.937 g·mol−11.00infobox
ErythromycinPDB ligandERY (PDBe, RCSB PDB)1.00infobox
ErythromycinPregnancy categoryAU: A1.00infobox
ErythromycinProtein binding90%1.00infobox
ErythromycinPubChem CID125601.00infobox
ErythromycinRoutes of administrationBy mouth, intravenous, intramuscular, topical, eye drops1.00infobox
ErythromycinTrade namesEryc, Erythrocin, others1.00infobox
ErythromycinUNII63937KV33D1.00infobox

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