Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Rabeprazole

Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production such as in Zollinger–Ellison syndrome. It may also be used in combination with other medications to treat Helicobacter pylori.…

History, Community, Culture & Applications

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Rabeprazole. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A02BC04 (WHO) A02BC54 (WHO) A02BD12 (WHO) A02BD13 (WHO)
Bioavailability
52%
CAS Number
117976-89-3 Y
ChEBI
CHEBI:8768 Y

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Rabeprazole

Nodes177
Edges176
Triples231
Avg. degree1.99
Density0.011299
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Rabeprazole

Top relations

related to Medical uses · 17
Rabeprazole → Acid, GERD, H2, Helicobacter, IGAH, In, MEN-1, Notably, Only, PPI, PPIs, South Korean, The, There, This, ZES, Zollinger-Ellison
related to References · 15
Rabeprazole → CC-BY-SA-3, ISSN, Joseph Cusimano, Lock-gray-alt-2, Lock-green, Lock-red-alt-2, Medicine, November, PDF, The, This, Wikidata Q113996572, WikiJournal, Wikipedia, Wikisource-logo
related to Infection risk · 14
Rabeprazole → Both, Campylobacter, Clostridioides, However, In, It, Japanese, One, Other, PPI, PPI-associated, PPI-induced, PPIs, Salmonella
related to Mechanism of action · 14
Rabeprazole → After, At, ATPase, Due, HCl, Here, However, Like, Once, PPIs, Rabeprazole's, These, This, Thus
related to Comparative chemistry · 13
Rabeprazole → CF3-CH2-O, CH2, CH3-O, CH3O, CHF2O, Comparative, Esomeprazole, Lansoprazole, Omeprazole, PPI, PPIs, Table, The
related to Pharmacogenetics · 13
Rabeprazole → Asian, Caucasian, Conversely, CYP2C19, For, However, In, Japanese, People, The, Therefore, This, United States
has effect · 11
Rabeprazole → Characteristic, Clostridioides, CYP2C19, ECL, Enterochromafin-like, Gastrin, Hypergastrinemia, In, PPIs, Rare, The
related to Development · 10
Rabeprazole → August, Developed, E3810, Eisai Medical Research, February, LY307640, October, On August, The, US
related to Nephrotoxicity · 10
Rabeprazole → AIN, AKI, Australia, CKD, Forms, GERD, It, PPI-induced, PPIs, The
related to Pharmacokinetics · 9
Rabeprazole → CYP2C19, CYP3A4, However, It, Once, Oral, Rabeprazole's, Some, The

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

acid ppis stomach omeprazole cyp2c19 drug rabeprazole's like may ppi used include effect side use esomeprazole effects treatment medication gastric

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Rabeprazole3D model (JSmol)Interactive image1.00infobox
RabeprazoleAHFS/Drugs.comMonograph1.00infobox
RabeprazoleATC codeA02BC04 (WHO) A02BC54 (WHO) A02BD12 (WHO) A02BD13 (WHO)1.00infobox
RabeprazoleBioavailability52%1.00infobox
RabeprazoleCAS Number117976-89-3 Y1.00infobox
RabeprazoleChEBICHEBI:8768 Y1.00infobox
RabeprazoleChEMBLChEMBL1219 Y1.00infobox
RabeprazoleChemSpider4853 Y1.00infobox
RabeprazoleChiralityRacemic mixture1.00infobox
RabeprazoleCompTox Dashboard (EPA)DTXSID30441221.00infobox
RabeprazoleDrug classProton pump inhibitor1.00infobox
RabeprazoleDrugBankDB01129 Y1.00infobox
RabeprazoleECHA InfoCard100.123.4081.00infobox
RabeprazoleElimination half-life~1 hour1.00infobox
RabeprazoleExcretion90% via kidney as metabolites1.00infobox
RabeprazoleFormulaC18H21N3O3S1.00infobox
RabeprazoleIUPHAR/BPS72901.00infobox
RabeprazoleKEGGD08463 Y1.00infobox
RabeprazoleKEGGC07864 Y1.00infobox
RabeprazoleLegal statusUK: POM (Prescription only)1.00infobox
RabeprazoleLegal statusUS: ℞-only1.00infobox
RabeprazoleLicense dataUS DailyMed: Rabeprazole1.00infobox
RabeprazoleLicense dataUS FDA: Rabeprazole1.00infobox
RabeprazoleMedlinePlusa6990601.00infobox
RabeprazoleMetabolismCYP2C19 and CYP3A4 in the liver1.00infobox
RabeprazoleMetabolitesthioether carboyxlic acid metabolite, thioether glucuronide metabolite, sulfone metabolite1.00infobox
RabeprazoleMolar mass359.44 g·mol−11.00infobox
RabeprazolePDB ligandRZX (PDBe, RCSB PDB)1.00infobox
RabeprazolePregnancy categoryAU: B11.00infobox
RabeprazolePronunciation/rəˈbɛprəˌzɔːl/1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.