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Tobramycin

Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas.

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Explore the main themes, entities and connections around Tobramycin. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01GB01 (WHO) S01AA12 (WHO)
CAS Number
32986-56-4 Y
ChEBI
CHEBI:28864 Y
ChEMBL
ChEMBL1747 Y

Topics to explore

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Overview

Medical uses

Contraindications

Side effects

Interactions

Pharmacology

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Tobramycin

Nodes78
Edges77
Triples84
Avg. degree1.97
Density0.025641
Components1

How this topic connects Entity context

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Tobramycin

Top relations

related to Mechanism of action · 8
Tobramycin → As, However, Krebs, RNA-aptamers, RNAs, TCA, The, These
related to Medical uses · 7
Tobramycin → Eye, Nebcin, Pseudomonas, The, Tobi, Tobradex, Tobrex
related to Pharmacokinetics · 7
Tobramycin → Elimination, In, It, Only, People, The, When
related to Society and culture · 7
Tobramycin → Alcon Pharmaceuticals, Benzalkonium, Essential Medicines, In, Tobrex, United States, World Health Organization's List
related to Spectrum of susceptibility · 7
Tobramycin → ATCC, Clinically, Gram-negative, Gram-positive Staphylococcus, MIC, Pseudomonas, The
Legal status · 6
Tobramycin → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
has effect · 5
Tobramycin → Adequate, For, Like, Nephrotoxicity, Other
related to Interactions · 4
Tobramycin → Likewise, Methoxyflurane, Muscle, Other
related to Brand names · 3
Tobramycin → EIPICo, In Egypt, Tobrin
KEGG · 2
Tobramycin → C00397 Y, D00063 Y

Important terminology Word statistics

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Important terminology

effects medical pseudomonas people also side tobrex half-life bacterial eye drops form citation needed used various infections use brand aminoglycoside

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Tobramycin3D model (JSmol)Interactive image1.00infobox
TobramycinAHFS/Drugs.comMonograph1.00infobox
TobramycinATC codeJ01GB01 (WHO) S01AA12 (WHO)1.00infobox
TobramycinCAS Number32986-56-4 Y1.00infobox
TobramycinChEBICHEBI:28864 Y1.00infobox
TobramycinChEMBLChEMBL1747 Y1.00infobox
TobramycinChemSpider33377 Y1.00infobox
TobramycinCompTox Dashboard (EPA)DTXSID80236801.00infobox
TobramycinDrugBankDB00684 Y1.00infobox
TobramycinECHA InfoCard100.046.6421.00infobox
TobramycinElimination half-life2–3 hrs1.00infobox
TobramycinExcretionExclusively via kidneys1.00infobox
TobramycinFormulaC18H37N5O91.00infobox
TobramycinKEGGD00063 Y1.00infobox
TobramycinKEGGC00397 Y1.00infobox
TobramycinLegal statusAU: S4 (Prescription only)1.00infobox
TobramycinLegal statusCA: ℞-only1.00infobox
TobramycinLegal statusUK: POM (Prescription only)1.00infobox
TobramycinLegal statusUS: ℞-only1.00infobox
TobramycinLegal statusEU: Rx-only1.00infobox
TobramycinLegal statusIn general: ℞ (Prescription only)1.00infobox
TobramycinLicense dataUS DailyMed: Tobramycin1.00infobox
TobramycinMedlinePlusa6826601.00infobox
TobramycinMetabolismNot metabolized1.00infobox
TobramycinMolar mass467.520 g·mol−11.00infobox
TobramycinOther names47663, SPRC-AB011.00infobox
TobramycinPDB ligandTOY (PDBe, RCSB PDB)1.00infobox
TobramycinPregnancy categoryAU: D1.00infobox
TobramycinProtein bindingNot bound1.00infobox
TobramycinPubChem CID362941.00infobox

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