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Neomycin: Applications, Medical uses & Mechanism of action

Neomycin, also known as framycetin, is an aminoglycoside antibiotic that displays bactericidal activity against Gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against Gram-positive bacilli and anaerobic Gram-negative bacilli. Neomycin comes in oral and topical formulations…

Language: English [EN]
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Neomycin topic overview

The analysis highlights Applications, Medical uses and Mechanism of action as prominent areas in the source structure around Neomycin.

Related topics
80
Source areas
8
Connected nodes
88
Extracted relationships
120
Concept neighborhoods
26
Bridge connections
88

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Medical uses · 20 topics
Mechanism of action · 12 topics
Biosynthetic pathway · 11 topics
Additional activities · 10 topics
Overview · 10 topics
Side effects · 9 topics
Chemistry · 7 topics
Discovery · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A01AB08 (WHO) A07AA01 (WHO), B05CA09 (WHO), D06AX04 (WHO), J01GB05 (WHO), R02AB01 (WHO), S01AA03 (WHO), S02AA07 (WHO), S03AA01 (WHO)
Bioavailability
< 3% (oral)
CAS Number
1404-04-2 Y
ChEBI
CHEBI:7508 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Medical uses

Side effects

Mechanism of action

Chemistry

Biosynthetic pathway

Additional activities

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Neomycin connects Entity context

The extracted context around Neomycin shows recurring relationship patterns in the source. For example, Neomycin → Although, An, In, IRF3, IRF7, ISG, ISGs, It, Neosporin, The, TICAM1, TLR3, Yale University, Zika Another extracted example is Neomycin → C-5, D-neosamine, D-ribose, DOS, II, II-I-III-IV, III, IV, L-neosamine, Ring, The, Three. Use these groups to spot repeated connection types before inspecting the individual relationships.

Neomycin

Top relations

related to Immunostimulation · 14
Neomycin → Although, An, In, IRF3, IRF7, ISG, ISGs, It, Neosporin, The, TICAM1, TLR3, Yale University, Zika
related to Structure · 12
Neomycin → C-5, D-neosamine, D-ribose, DOS, II, II-I-III-IV, III, IV, L-neosamine, Ring, The, Three
related to Resistance · 11
Neomycin → Although, APH, APH/neo, As, Currently, DNA, G418, Many, Other, Specific, This
has effect · 9
Neomycin → Allergen, Although, Hearing, In, It, Like, Patients, Routes, Year
related to DNA binding · 9
Neomycin → A-form, A-site RNA, Aminoglycosides, B-DNA, DNA, DNA-binding, However, RNA, The
related to Medical uses · 9
Neomycin → B/bacitracin, B/hydrocortisone, By, In, It, Neosporin, Orally, The, United States
related to Spectrum · 9
Neomycin → Enterobacter, Gram-negative, Gram-positive, It, MIC, Physicians, Polysporin, Similar, The
related to Biosynthetic pathway · 7
Neomycin → Addition, In, N-acetylparomamine, Production, Streptomyces, The, UDP-N-acetylglucosamine
related to Discovery · 7
Neomycin → Hubert Lechevalier, It, Rutgers University, Selman Waksman, Streptomyces, Synthesis, The
related to Composition · 5
Neomycin → NBRC, Pharmaceutical, Streptomyces, The, This

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

also topical aminoglycosides gram-negative used activity antibiotic bacteria known university oral dna aminoglycoside ribostamycin binding cell gene one effective use

Neomycin relationships Subject–Predicate–Object triples

TTTA extracted 120 structured relationships around Neomycin. Examples in this analysis include Neomycin → 3D model (JSmol) → Interactive image and Neomycin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Neomycin3D model (JSmol)Interactive image1.00infobox
NeomycinAHFS/Drugs.comMonograph1.00infobox
NeomycinATC codeA01AB08 (WHO) A07AA01 (WHO), B05CA09 (WHO), D06AX04 (WHO), J01GB05 (WHO), R02AB01 (WHO), S01AA03 (WHO), S02AA07 (WHO), S03AA01 (WHO)1.00infobox
NeomycinBioavailability< 3% (oral)1.00infobox
NeomycinCAS Number1404-04-2 Y1.00infobox
NeomycinChEBICHEBI:7508 Y1.00infobox
NeomycinChEMBLChEMBL449118 N1.00infobox
NeomycinChemSpider8075 Y1.00infobox
NeomycinDrugBankDB00994 Y1.00infobox
NeomycinECHA InfoCard100.014.3331.00infobox
NeomycinElimination half-life2 to 3 hours1.00infobox
NeomycinFormulaC23H46N6O131.00infobox
NeomycinIUPHAR/BPS7091.00infobox
NeomycinKEGGD08260 Y1.00infobox
NeomycinLegal statusUS: ℞-only but OTC in Neosporin and similar ointments1.00infobox
NeomycinMedlinePlusa6822741.00infobox
NeomycinMetabolism(Not used systemically)1.00infobox
NeomycinMolar mass614.650 g·mol−11.00infobox
NeomycinProtein binding(Not used systemically)1.00infobox
NeomycinPubChem CID83781.00infobox
NeomycinRoutes of administrationTopical, oral1.00infobox
NeomycinTrade namesNeo-rx1.00infobox
NeomycinUNIII16QD7X2971.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Neomycin bring nearby vocabulary together. In this analysis, examples include Bacteria, Aminoglycosides and Dna. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Neomycin
    • Bacteria
    • Aminoglycosides
    • Dna
    • One
    • Topical
    • Ointments
    • Resistance
    • Rutgers
    • Waksman
    • 2-deoxystreptamine
    • Effective
    • Ring
  • neomycin
    • Bacteria
    • Aminoglycosides
    • Dna
    • One
    • Topical
    • Ointments
    • Resistance
    • Rutgers
    • Waksman
    • 2-deoxystreptamine
    • Effective
    • Ring
  • neomycin/polymyxin b/bacitracin
    • Bacteria
    • Aminoglycosides
    • Dna
    • One
    • Topical
    • Ointments
    • Resistance
    • Rutgers
    • Waksman
    • 2-deoxystreptamine
    • Effective
    • Ring
  • neomycin/polymyxin b/hydrocortisone
    • Bacteria
    • Aminoglycosides
    • Dna
    • One
    • Topical
    • Ointments
    • Resistance
    • Rutgers
    • Waksman
    • 2-deoxystreptamine
    • Effective
    • Ring
  • neomycin a
    • Bacteria
    • Aminoglycosides
    • Dna
    • One
    • Topical
    • Ointments
    • Resistance
    • Rutgers
    • Waksman
    • 2-deoxystreptamine
    • Effective
    • Ring
  • neomycin c epimerase
    • Bacteria
    • Aminoglycosides
    • Dna
    • One
    • Topical
    • Ointments
    • Resistance
    • Rutgers
    • Waksman
    • 2-deoxystreptamine
    • Effective
    • Ring
  • antibiotic
    • Resistance
    • Anaerobic
    • Bacilli
    • Framycetin
    • Ointments
    • Commonly
    • Effective
    • Using
    • Activity
    • Gene
    • Gram-negative
    • Known
  • selman waksman
    • Rutgers
    • University
    • Binding
    • Ointments
    • Resistance
    • Oral
    • Activity
    • Dna
    • Bacteria
    • Topical
    • Used
    • Neomycin

Connections between topic areas Semantic bridges

For Neomycin, one of the stronger structural bridges in this analysis connects Neomycin with Medical uses. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Neomycin — Medical uses · splits 68 ⟂ 21
Neomycin — Mechanism of action · splits 76 ⟂ 13
Neomycin — Biosynthetic pathway · splits 77 ⟂ 12
Neomycin — Overview · splits 78 ⟂ 11
Neomycin — Additional activities · splits 78 ⟂ 11
Neomycin — Side effects · splits 79 ⟂ 10
Neomycin — Chemistry · splits 81 ⟂ 8

Map overview Semantic statistics

Neomycin

Nodes89
Edges88
Triples120
Avg. degree1.98
Density0.022472
Components1

Source & methodology

TTTA analyzes the structure around Neomycin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Medical uses & Mechanism of action, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Neomycin · EN edition · Analysis: TopicsToTalkAbout

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