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Gentamicin: History, Applications & Research

Gentamicin is an aminoglycoside antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It can be given intravenously, by intramuscular injection, or topically. Topical formulations may be used in…

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Gentamicin topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Gentamicin.

Related topics
141
Source areas
8
Connected nodes
149
Extracted relationships
115
Related term clusters
25
Bridge connections
149

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 58 topics
Adverse effects · 23 topics
Chemistry · 18 topics
Medical uses · 18 topics
Pharmacology · 13 topics
History · 5 topics
Contraindications · 4 topics
Research · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
C1: Interactive image
AHFS/Drugs.com
Monograph
ATC code
C1: D06AX07 (WHO) J01GB03 (WHO) S01AA11 (WHO) S02AA14 (WHO) S03AA06 (WHO) QA07AA91 (WHO) QG01AA91 (WHO) QG51AA04 (WHO) QJ51GB03 (WHO)
Bioavailability
limited bioavailability by mouth
CAS Number
1403-66-3 Y
ChEBI
C1: CHEBI:27412 Y

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects

Pharmacology

Chemistry

History

Research

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Gentamicin connects Entity context

The extracted context around Gentamicin shows recurring relationship patterns in the source. For example, Gentamicin → A2, C-methylated, C1, C2a, C6, D-glucosamine, D-Glucose-6-phosphate, D-xylose, DOG, G418, G418 G418, GenB1, GenB2, GenK, GenQ, Gentamicin A2, JI-20B, Literature, Many, Micromonospora Another extracted example is Gentamicin → According, American Medical Association Committee, Atlanta, Bloomfield, Cooper, Generic Names, Gentian Violet, Gram-positive, IV, Micromonospora, Rico Woyciesjes, San Antonio, Schering Corporation, Streptomyces, Subsequently, Wagman, Weinstein. Use these groups to spot repeated connection types before inspecting the individual relationships.

Gentamicin

Top relations

related to Biosynthesis · 25
Gentamicin → A2, C-methylated, C1, C2a, C6, D-glucosamine, D-Glucose-6-phosphate, D-xylose, DOG, G418, G418 G418, GenB1, GenB2, GenK, GenQ, Gentamicin A2, JI-20B, Literature, Many, Micromonospora
related to history · 17
Gentamicin → According, American Medical Association Committee, Atlanta, Bloomfield, Cooper, Generic Names, Gentian Violet, Gram-positive, IV, Micromonospora, Rico Woyciesjes, San Antonio, Schering Corporation, Streptomyces, Subsequently, Wagman, Weinstein
related to Medical uses · 12
Gentamicin → Enterobacter, Escherichia, Francisella, Gram-negative, Gram-positive Staphylococcus, Klebsiella, Legionella, Neisseria, Proteus, Pseudomonas, Serratia, Yersinia
related to Structure · 11
Gentamicin → C1, C1a, C2, C2a, C2b, Gentamicins, Micromonospora, R1, R2, Since, The R1
has effect · 4
Gentamicin → Adverse, Ear, Kidney, Low
related to Kidney damage · 4
Gentamicin → Factors, Kidney, NSAIDs, Oftentimes
related to Mechanism of action · 4
Gentamicin → Elongation Factor Thermo-Unstable, Moreover, RNA, Typically
related to Components · 3
Gentamicin → C1, C1a, C2
Legal status · 2
Gentamicin → EU: Rx-only, In general: ℞ (Prescription only)
is a · 2
Gentamicin → aminoglycoside antibiotic used to treat several types of bacterial infections, type of aminoglycoside and works by disrupting the ability of the bacteria to make proteins

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

used antibiotic ear micromonospora inner biosynthesis kidney may complex include use infections problems damage components also bacterial pregnancy treatment aminoglycoside

Gentamicin relationships Subject–Predicate–Object triples

TTTA extracted 115 structured relationships around Gentamicin. Examples in this analysis include Gentamicin → 3D model (JSmol) → C1: Interactive image and Gentamicin → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Gentamicin3D model (JSmol)C1: Interactive image1.00infobox
GentamicinAHFS/Drugs.comMonograph1.00infobox
GentamicinATC codeC1: D06AX07 (WHO) J01GB03 (WHO) S01AA11 (WHO) S02AA14 (WHO) S03AA06 (WHO) QA07AA91 (WHO) QG01AA91 (WHO) QG51AA04 (WHO) QJ51GB03 (WHO)1.00infobox
GentamicinBioavailabilitylimited bioavailability by mouth1.00infobox
GentamicinCAS Number1403-66-3 Y1.00infobox
GentamicinChEBIC1: CHEBI:27412 Y1.00infobox
GentamicinChEMBLC1: ChEMBL195892 Y1.00infobox
GentamicinChemSpiderC1: 390067 Y1.00infobox
GentamicinCompTox Dashboard (EPA)C1: DTXSID50346421.00infobox
GentamicinDrug classAminoglycoside antibiotic1.00infobox
GentamicinDrugBankC1: DB00798 N1.00infobox
GentamicinECHA InfoCard100.014.3321.00infobox
GentamicinElimination half-life2 h1.00infobox
GentamicinExcretionKidney1.00infobox
GentamicinFormulaC21H43N5O71.00infobox
GentamicinIUPHAR/BPSC1: 24271.00infobox
GentamicinKEGGC1: D08013 Y1.00infobox
GentamicinLegal statusEU: Rx-only1.00infobox
GentamicinLegal statusIn general: ℞ (Prescription only)1.00infobox
GentamicinLicense dataUS DailyMed: Gentamicin1.00infobox
GentamicinMedlinePlusa6822751.00infobox
GentamicinMolar mass477.603 g·mol−11.00infobox
GentamicinPregnancy categoryAU: D1.00infobox
GentamicinPronunciation/ˌdʒɛntəˈmaɪsən/1.00infobox
GentamicinProtein binding0–10%1.00infobox
GentamicinPubChem CIDC1: 34671.00infobox
GentamicinRoutes of administrationIntravenous, eye drop, Intramuscular injection, Topical administration, ear drop1.00infobox
GentamicinTrade namesCidomycin, Genticyn, Garamycin, others1.00infobox
GentamicinUNIIT6Z9V48IKG Y1.00infobox
Gentamicinis aaminoglycoside antibiotic used to treat several types of bacterial infections0.90text

Related concept clusters Related term clusters

The concept neighborhoods around Gentamicin bring nearby vocabulary together. In this analysis, examples include Used, Complex and Biosynthesis. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • antibiotic
    • Cell
    • Increase
    • Bacterial
    • Biosynthesis
    • Others
    • Research
    • Higher
    • Gentamicin
    • Infections
    • Kidney
    • Damage
    • Inner
  • bacterial infections
    • Infections
    • Others
    • Used
    • Risk
    • Kidney
    • May
    • Damage
    • Inner
    • Ear
    • Intramuscular
    • Cause
    • Fermentation
  • bacterial cultures
    • Infections
    • Risk
    • Kidney
    • Damage
    • Inner
    • Used
    • Ear
    • Intramuscular
    • Cause
    • Fermentation
    • Injection
    • Others
  • Gentamicin
    • Used
    • Complex
    • Biosynthesis
    • Also
    • Components
    • Micromonospora
    • Found
    • Bacterial
    • Growth
    • Kidney
    • Fermentation
    • Research
  • gentamicin
    • Used
    • Complex
    • Biosynthesis
    • Also
    • Components
    • Micromonospora
    • Found
    • Bacterial
    • Growth
    • Kidney
    • Fermentation
    • Research
  • inner ear problems
    • Inner
    • Damage
    • Problems
    • Kidney
    • Include
    • Blood
    • Higher
    • Nephrotoxicity
    • Intramuscular
    • Fermentation
    • Others
    • Pregnancy
  • nerve damage
    • Ear
    • Inner
    • Kidney
    • Blood
    • Higher
    • Problems
    • Include
    • Intramuscular
    • Fermentation
    • Injection
    • Nephrotoxicity
    • Neuromuscular
  • kidney damage
    • Ear
    • Inner
    • Damage
    • Kidney
    • Blood
    • Nephrotoxicity
    • Pregnancy
    • Higher
    • Increase
    • Levels
    • Therapy
    • Problems

Connections between topic areas Semantic bridges

For Gentamicin, one of the stronger structural bridges in this analysis connects Gentamicin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Gentamicin — Overview · splits 91 ⟂ 59
Gentamicin — Adverse effects · splits 126 ⟂ 24
Gentamicin — Medical uses · splits 131 ⟂ 19
Gentamicin — Chemistry · splits 131 ⟂ 19
Gentamicin — Pharmacology · splits 136 ⟂ 14
Gentamicin — History · splits 144 ⟂ 6
Gentamicin — Contraindications · splits 145 ⟂ 5
Gentamicin — Research · splits 147 ⟂ 3

Map overview Semantic statistics

Gentamicin

Nodes150
Edges149
Triples115
Avg. degree1.99
Density0.013333
Components1

Source & methodology

TTTA analyzes the structure around Gentamicin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Gentamicin · EN edition · Analysis: TopicsToTalkAbout

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