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Gentamicin

Gentamicin is an aminoglycoside antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It can be given intravenously, by intramuscular injection, or topically. Topical formulations may be used in…

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Key facts & relationships

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3D model (JSmol)
C1: Interactive image
AHFS/Drugs.com
Monograph
ATC code
C1: D06AX07 (WHO) J01GB03 (WHO) S01AA11 (WHO) S02AA14 (WHO) S03AA06 (WHO) QA07AA91 (WHO) QG01AA91 (WHO) QG51AA04 (WHO) QJ51GB03 (WHO)
Bioavailability
limited bioavailability by mouth
CAS Number
1403-66-3 Y
ChEBI
C1: CHEBI:27412 Y

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Overview

Medical uses

Contraindications

Adverse effects

Pharmacology

Chemistry

History

Research

Advanced semantic analysis

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Map overview Semantic statistics

Gentamicin

Nodes156
Edges155
Triples134
Avg. degree1.99
Density0.012821
Components1

How this topic connects Entity context

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Gentamicin

Top relations

related to Biosynthesis · 26
Gentamicin → A2, C-methylated, C1, C2a, C6, D-glucosamine, D-Glucose-6-phosphate, D-xylose, DOG, G418, G418 G418, GenB1, GenB2, GenK, GenQ, Gentamicin A2, JI-20B, Literature, Many, Micromonospora
related to history · 19
Gentamicin → According, American Medical Association Committee, Atlanta, Bloomfield, Cooper, Generic Names, Gentian Violet, Gram-positive, It, IV, Micromonospora, Rico Woyciesjes, San Antonio, Schering Corporation, Streptomyces, Subsequently, Wagman, Weinstein, When
related to Medical uses · 13
Gentamicin → Enterobacter, Escherichia, Francisella, Gram-negative, Gram-positive Staphylococcus, Klebsiella, Legionella, Neisseria, Proteus, Pseudomonas, Serratia, There, Yersinia
related to Structure · 13
Gentamicin → C1, C1a, C2, C2a, C2b, Gentamicins, Micromonospora, R1, R2, Since, The, The R1, This
related to Mechanism of action · 9
Gentamicin → An, At, Elongation Factor Thermo-Unstable, However, Moreover, RNA, The, This, Typically
related to Inner ear · 7
Gentamicin → About, Chronic, Factors, First, Second, The, To
related to Components · 5
Gentamicin → Because, C1, C1a, C2, The
related to Kidney damage · 5
Gentamicin → Factors, Kidney, NSAIDs, Oftentimes, The
has effect · 4
Gentamicin → Adverse, Ear, Kidney, Low
Legal status · 2
Gentamicin → EU: Rx-only, In general: ℞ (Prescription only)

Important terminology Word statistics

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Important terminology

used antibiotic ear micromonospora inner biosynthesis kidney may complex include use infections problems damage components also bacterial pregnancy treatment aminoglycoside

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Gentamicin3D model (JSmol)C1: Interactive image1.00infobox
GentamicinAHFS/Drugs.comMonograph1.00infobox
GentamicinATC codeC1: D06AX07 (WHO) J01GB03 (WHO) S01AA11 (WHO) S02AA14 (WHO) S03AA06 (WHO) QA07AA91 (WHO) QG01AA91 (WHO) QG51AA04 (WHO) QJ51GB03 (WHO)1.00infobox
GentamicinBioavailabilitylimited bioavailability by mouth1.00infobox
GentamicinCAS Number1403-66-3 Y1.00infobox
GentamicinChEBIC1: CHEBI:27412 Y1.00infobox
GentamicinChEMBLC1: ChEMBL195892 Y1.00infobox
GentamicinChemSpiderC1: 390067 Y1.00infobox
GentamicinCompTox Dashboard (EPA)C1: DTXSID50346421.00infobox
GentamicinDrug classAminoglycoside antibiotic1.00infobox
GentamicinDrugBankC1: DB00798 N1.00infobox
GentamicinECHA InfoCard100.014.3321.00infobox
GentamicinElimination half-life2 h1.00infobox
GentamicinExcretionKidney1.00infobox
GentamicinFormulaC21H43N5O71.00infobox
GentamicinIUPHAR/BPSC1: 24271.00infobox
GentamicinKEGGC1: D08013 Y1.00infobox
GentamicinLegal statusEU: Rx-only1.00infobox
GentamicinLegal statusIn general: ℞ (Prescription only)1.00infobox
GentamicinLicense dataUS DailyMed: Gentamicin1.00infobox
GentamicinMedlinePlusa6822751.00infobox
GentamicinMolar mass477.603 g·mol−11.00infobox
GentamicinPregnancy categoryAU: D1.00infobox
GentamicinPronunciation/ˌdʒɛntəˈmaɪsən/1.00infobox
GentamicinProtein binding0–10%1.00infobox
GentamicinPubChem CIDC1: 34671.00infobox
GentamicinRoutes of administrationIntravenous, eye drop, Intramuscular injection, Topical administration, ear drop1.00infobox
GentamicinTrade namesCidomycin, Genticyn, Garamycin, others1.00infobox
GentamicinUNIIT6Z9V48IKG Y1.00infobox
Gentamicinis aaminoglycoside antibiotic used to treat several types of bacterial infections0.90text

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