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Cubam: Clinical significance & Overview

Cubam is the term used to refer to a multi-ligand receptor located in the terminal ileum, specializing in absorption of vitamin B12. Cubam is essentially composed of amnionless (AMN), and cubilin. Cubilin is essential as a cell receptor recognizing the "vitamin B12-intrinsic factor" complex, whereas amnionless is more involved in the receptor mediated…

Language: English [EN]
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Cubam topic overview

The analysis highlights Clinical significance and Overview as prominent areas in the source structure around Cubam.

Related topics
16
Source areas
2
Connected nodes
18
Extracted relationships
27
Concept neighborhoods
13
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 11 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
PRO1028
Domains
InterPro
HGNC
14604
Locus
Chr. 14 q32.32
NCBI gene
81693
OMIM
605799

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cubam connects Entity context

The extracted context around Cubam shows recurring relationship patterns in the source. For example, Cubam → AMN, As, Autosomal, B12, Cubilin, CUBN, However, IF, IGS, Imerslund-Gräsbeck, Rarely, Severe, The, This, Vitamin B12 Another extracted example is Cubam → PRO1028. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cubam

Top relations

related to Clinical significance · 15
Cubam → AMN, As, Autosomal, B12, Cubilin, CUBN, However, IF, IGS, Imerslund-Gräsbeck, Rarely, Severe, The, This, Vitamin B12
Alt. symbols · 1
Cubam → PRO1028
Domains · 1
Cubam → InterPro
HGNC · 1
Cubam → 14604
Locus · 1
Cubam → Chr. 14 q32.32
NCBI gene · 1
Cubam → 81693
OMIM · 1
Cubam → 605799
RefSeq · 1
Cubam → NM_030943
Search for · 1
Cubam → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Cubam → Swiss-model

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vitamin cubilin b12 amnionless amn factor anemia essential receptor ileum intrinsic cause deficiency imerslund-gräsbeck syndrome terminal absorption mediated chr 14

Cubam relationships Subject–Predicate–Object triples

TTTA extracted 27 structured relationships around Cubam. Examples in this analysis include Cubam → Alt. symbols → PRO1028 and Cubam → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CubamAlt. symbolsPRO10281.00infobox
CubamDomainsInterPro1.00infobox
CubamHGNC146041.00infobox
CubamLocusChr. 14 q32.321.00infobox
CubamNCBI gene816931.00infobox
CubamOMIM6057991.00infobox
CubamRefSeqNM_0309431.00infobox
CubamSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CubamStructuresSwiss-model1.00infobox
CubamSymbolAMN1.00infobox
CubamUniProtQ9BXJ71.00infobox
Cubamis aterm used to refer to a multi-ligand receptor located in the terminal ileum0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cubam bring nearby vocabulary together. In this analysis, examples include Absorption, Ileum and Terminal. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cubam
    • Absorption
    • Ileum
    • Terminal
    • Amn
    • Composed
    • Cubilin
    • Essentially
    • Located
    • Multi-ligand
    • Refer
    • Specializing
    • Term
  • cubam
    • Absorption
    • Ileum
    • Terminal
    • Amn
    • Composed
    • Cubilin
    • Essentially
    • Located
    • Multi-ligand
    • Refer
    • Specializing
    • Term
  • vitamin b12
    • B12
    • Vitamin
    • Factor
    • Cause
    • Deficiency
    • Intrinsic
    • Ileum
    • Terminal
    • Absorption
    • Imerslund-gräsbeck
    • Mediated
    • Receptor
  • amnionless
    • Cubilin
    • Amn
    • B12-intrinsic
    • Cell
    • Composed
    • Endocytosis
    • Essentially
    • Recognizing
    • Also
    • Autosomal
    • Gene
    • Mediated
  • cubilin
    • Autosomal
    • Recessive
    • Essential
    • Imerslund-gräsbeck
    • Syndrome
    • B12-intrinsic
    • Cell
    • Endocytosis
    • Essentially
    • Recognizing
    • Vitamin
    • Also
  • ileum
    • Terminal
    • Located
    • Multi-ligand
    • Refer
    • Specializing
    • Term
    • Used
    • Q32
    • Receptor
    • Essential
    • Intrinsic
    • Vitamin
  • macrocytic anemia
    • Macrocytic
    • Cause
    • Imerslund-gräsbeck
    • Syndrome
    • Autosomal
    • Recessive
    • B12
    • Also
    • Vitamin
    • Cubam
    • Cubilin
  • pernicious anemia
    • Macrocytic
    • Cause
    • Imerslund-gräsbeck
    • Syndrome
    • B12
    • Also
    • Autosomal
    • Recessive
    • Vitamin
    • Cubam
    • Cubilin

Connections between topic areas Semantic bridges

For Cubam, one of the stronger structural bridges in this analysis connects Cubam with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CubamClinical significance · splits 7 ⟂ 12
CubamOverview · splits 13 ⟂ 6

Map overview Semantic statistics

Cubam

Nodes19
Edges18
Triples27
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around Cubam to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cubam · EN edition · Analysis: TopicsToTalkAbout

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