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Pepsin

Pepsin /ˈpɛpsɪn/ is an endopeptidase that breaks down proteins into smaller peptides and amino acids. It is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Pepsin is an aspartic protease, using a catalytic aspartate in its active site.

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Key facts & relationships

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BRENDA
enzyme data
CAS no.
9001-75-6
EC no.
3.4.23.1
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Topics to explore

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Overview

History

Precursor

Activity and stability

In laryngopharyngeal reflux

Inhibitors

Applications

Advanced semantic analysis

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Map overview Semantic statistics

Pepsin

Nodes65
Edges64
Triples103
Avg. degree1.97
Density0.030769
Components1

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Pepsin

Top relations

related to External links · 24
Pepsin → A01, Archived, Beemans GumPepsin, David Goodsell, Gastricsin, Human Gastricsin, Medicine Medical Subject Headings, MeSH, Molecule, Month Archived, National Library, Overview, P0DJD7, P20142, PDB, PDBe-KB, Pepsin A-4, Pepsinogen, Pepsinogens, RCSB Protein Data BankOverview
has application · 18
Pepsin → Beeman, Beeman's, Commercial, Dr, Edwin, Fab, Fc, For, IgG, In, It, One, Papain, Pepsodent, The, The Fc, This, To
related to Inhibitors · 15
Pepsin → Activity, Amino, Ascaris, Cu, Gln-Phe-Leu, II, Ki, N-terminal, P1, P3, Pepstatin, PI-3, Porcine, The, The N-terminus
related to In laryngopharyngeal reflux · 8
Pepsin → Exposure, Such, The, This, Under, Upon, Weak, While
related to history · 7
Pepsin → An, Greek, In, John, Northrop, Schwann, Theodor Schwann
related to Activity and stability · 5
Pepsin → Accordingly, At, In, The, Therefore
related to Precursor · 5
Pepsin → HCl, Hydrochloric, In, The, This
BRENDA · 1
Pepsin → enzyme data
CAS no. · 1
Pepsin → 9001-75-6
EC no. · 1
Pepsin → 3.4.23.1

Important terminology Word statistics

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Important terminology

ph proteins reflux amino acids pepsinogen acid enzymes ab' fragments fab cleavage gastric stomach one pepstatin used active also cells

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PepsinBRENDAenzyme data1.00infobox
PepsinCAS no.9001-75-61.00infobox
PepsinEC no.3.4.23.11.00infobox
PepsinExPASyNiceZyme view1.00infobox
PepsinGene OntologyAmiGO / QuickGO1.00infobox
PepsinKEGGenzyme entry1.00infobox
PepsinMetaCycmetabolic pathway1.00infobox
PepsinNCBIproteins1.00infobox
PepsinPDB structuresRCSB PDB PDBe PDBsum1.00infobox
PepsinPMCarticles1.00infobox
PepsinPubMedarticles1.00infobox
PepsinRheareactions1.00infobox
PepsinSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox
Pepsincauseschanges in gene expression associated with inflammation0.90text
Pepsinis aaspartic protease0.90text

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