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Coagulation

Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel forming a blood clot. The process involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation results in hemostasis, the cessation of blood loss from a damaged vessel, allowing repair.

History, Physiology & Role in disease

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Overview

Physiology

Medical assessment

Role in disease

Pharmacology

History

Other species

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Map overview Semantic statistics

Coagulation

Nodes219
Edges218
Triples142
Avg. degree1.99
Density0.009132
Components1

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Coagulation

Top relations

related to Initial discoveries · 15
Coagulation → Alexander Schmidt, Arthus, At, Giulio Bizzozero, II, III, Its, IV, Paul Morawitz, Physiologist Johannes Müller, Platelets, Prosper Sylvain Denis, Rudolf Virchow, The, Theories
related to Medical assessment · 15
Coagulation → Clauss, Common, D-dimer, ELT, G20210A, INR, Leiden, Numerous, Other, PFA-100, PT, Russell's, Sonoclot, TCT, TEG
related to Nomenclature · 15
Coagulation → Assignment, Factor, Factor VI, Factor XIII, Fitzgerald Factor, Fletcher Factor, Hemostasis, ICTH, In, International Committee, Roman, The, This, Thrombosis, XII
related to Further reading · 13
Coagulation → Cell-based Model, Dougald, February, Haemostasis, Hematology/Oncology Clinics, Hemostasis, Hoffman, Maureane, Monroe, Monroe DM, North America, PMID, Thrombosis
related to Platelet disorders · 12
Coagulation → An, Bernard, Decreased, Examples, Glanzmann's, Ib-IX-V, Most, Platelet, Soulier, They, Von Willebrand, Willebrand
related to Anticoagulants · 11
Coagulation → Also, Anti-platelet, Anticoagulants, II, IIb/IIIa, IX, K-dependent, Of, VII, Warfarin, Xa
related to Coagulation cascade · 11
Coagulation → Factor IV, Factor XIII, FIV, FV, FVIII, FXIII, It, Roman, The, These, Tissue
related to Coagulation factor disorders · 11
Coagulation → Christmas, GPIb, Ib, In, IX, The, This, VIII, Von Willebrand, Willebrand, XI
related to Role in immune system · 9
Coagulation → Also, For, Gram-positive, Immunohemostasis, Immunothrombosis, In, Many, Mediators, The
related to Coagulation factors · 7
Coagulation → Factor, Factor VI, He, Paul Owren, The, Va, VI

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Important terminology

factor platelets platelet thrombin blood fibrin hemostasis activation factors tissue pathway cascade bleeding activated process formation form fibrinogen calcium glycoprotein

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Coagulationis apart of an integrated series of haemostatic reactions0.90text
Coagulationis atissue factor0.90text
Coagulationis ahorseshoe crab0.90text
formation of neutrophil extracellular traps.CofactorsVarious substances are required for the proper functioning of the coagulation cascadeinstance oftriggering procoagulant and proinflammatory responses0.80text
acenocoumarolinstance ofVitamin K epoxide reductase is pharmacologically important as a target of anticoagulant drugs warfarin and related coumarins0.80text
phenprocoumoninstance ofVitamin K epoxide reductase is pharmacologically important as a target of anticoagulant drugs warfarin and related coumarins0.80text
and dicumarolinstance ofVitamin K epoxide reductase is pharmacologically important as a target of anticoagulant drugs warfarin and related coumarins0.80text
formation of neutrophil extracellular trapsinstance oftriggering procoagulant and proinflammatory responses0.80text
warfarin.The quantitativeinstance ofto monitor dosing of oral anticoagulants0.80text
qualitative screening of fibrinogen is measured by the thrombin clotting timeinstance ofto monitor dosing of oral anticoagulants0.80text
Coagulationrelated to AnticoagulantsAnticoagulants0.60section
Coagulationrelated to AnticoagulantsAnti-platelet0.60section

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