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Phenprocoumon (marketed under the brand names Marcoumar, Marcumar and Falithrom) is a long-acting anticoagulant to be taken by mouth, and a coumarin derivative. It acts as a vitamin K antagonist and inhibits blood clotting (coagulation) by blocking synthesis of coagulation factors II, VII, IX and X. It is used for the prophylaxis and treatment of…
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Explore the main themes, entities and connections around Phenprocoumon. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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bleeding vitamin effect cyp2c9 warfarin blood drugs cyp3a4 inr coagulation used interactions half-life days drug therapy hours also factors large
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Phenprocoumon | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Phenprocoumon | AHFS/Drugs.com | International Drug Names | 1.00 | infobox |
| Phenprocoumon | ATC code | B01AA04 (WHO) | 1.00 | infobox |
| Phenprocoumon | Bioavailability | 100% | 1.00 | infobox |
| Phenprocoumon | CAS Number | 435-97-2 Y | 1.00 | infobox |
| Phenprocoumon | ChEBI | CHEBI:50438 Y | 1.00 | infobox |
| Phenprocoumon | ChEMBL | ChEMBL1465 Y | 1.00 | infobox |
| Phenprocoumon | ChemSpider | 10441592 Y | 1.00 | infobox |
| Phenprocoumon | CompTox Dashboard (EPA) | DTXSID5023459 | 1.00 | infobox |
| Phenprocoumon | DrugBank | DB00946 Y | 1.00 | infobox |
| Phenprocoumon | ECHA InfoCard | 100.006.464 | 1.00 | infobox |
| Phenprocoumon | Elimination half-life | 6–7 days | 1.00 | infobox |
| Phenprocoumon | Excretion | Kidney | 1.00 | infobox |
| Phenprocoumon | Formula | C18H16O3 | 1.00 | infobox |
| Phenprocoumon | IUPHAR/BPS | 6839 | 1.00 | infobox |
| Phenprocoumon | KEGG | D05457 Y | 1.00 | infobox |
| Phenprocoumon | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Phenprocoumon | MedlinePlus | a699003 | 1.00 | infobox |
| Phenprocoumon | Melting point | 177–181 °C (351–358 °F) | 1.00 | infobox |
| Phenprocoumon | Metabolism | Liver (CYP2C9, CYP3A4) | 1.00 | infobox |
| Phenprocoumon | Metabolites | Hydroxyl derivatives, glucuronides | 1.00 | infobox |
| Phenprocoumon | Molar mass | 280.323 g·mol−1 | 1.00 | infobox |
| Phenprocoumon | Pregnancy category | Contraindicated | 1.00 | infobox |
| Phenprocoumon | Protein binding | 99% | 1.00 | infobox |
| Phenprocoumon | PubChem CID | 9908 | 1.00 | infobox |
| Phenprocoumon | Routes of administration | By mouth | 1.00 | infobox |
| Phenprocoumon | Trade names | Marcoumar, Marcumar, Falithrom | 1.00 | infobox |
| Phenprocoumon | UNII | Q08SIO485D | 1.00 | infobox |
| Phenprocoumon | is a | inhibitor of the enzyme vitamin K epoxide reductase | 0.90 | text |
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